1. Neuronal Signaling
    Metabolic Enzyme/Protease
  2. Monoamine Oxidase
    Dopamine β-hydroxylase
  3. 4-Hydroxyderricin

4-Hydroxyderricin 

Cat. No.: HY-N7204
Handling Instructions

4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is a potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. 4-Hydroxyderricin also mildly inhibits DBH (dopamine β-hydroxylase) activity. 4-Hydroxyderricin has antidepressant activity.

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4-Hydroxyderricin Chemical Structure

4-Hydroxyderricin Chemical Structure

CAS No. : 55912-03-3

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Description

4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is a potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. 4-Hydroxyderricin also mildly inhibits DBH (dopamine β-hydroxylase) activity. 4-Hydroxyderricin has antidepressant activity[1].

IC50 & Target

IC50: 3.43 μM (MAO-B)[1]

Molecular Weight

338.40

Formula

C₂₁H₂₂O₄

CAS No.

55912-03-3

SMILES

O=C(C1=CC=C(OC)C(C/C=C(C)\C)=C1O)/C=C/C2=CC=C(O)C=C2

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

4-HydroxyderricinMonoamine OxidaseDopamine β-hydroxylaseMAODopamine beta-hydroxylaseDopamine beta-monooxygenaseDopamine β-monooxygenaseInhibitorinhibitorinhibit

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4-Hydroxyderricin
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