Methyl 4-(hydroxymethyl)bicyclo[2.2.2]octane-1-carboxylate
Based on 1 Customer Validation
Methyl 4-(hydroxymethyl)bicyclo[2.2.2]octane-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : 99.99%
- CAS No.: 94994-15-7
- Formula: C11H18O3
- Molecular Weight:198.26
-
Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
![Methyl 4-(hydroxymethyl)bicyclo[2.2.2]octane-1-carboxylate Chemical Structure](https://file.medchemexpress.com/product_pic/hy-w042100.gif "Click to View Methyl 4-(hydroxymethyl)bicyclo[2.2.2]octane-1-carboxylate Chemical Structure")
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
-
Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E706 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 94994-15-7
-
Appearance Solid
-
Molecular Weight 198.26
-
Formula C11H18O3
-
Color White to off-white
-
SMILES
O=C(OC)C12CCC(CO)(CC1)CC2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (504.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (242 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.0439 mL | 25.2194 mL | 50.4388 mL | 126.0970 mL |
| 5 mM | 1.0088 mL | 5.0439 mL | 10.0878 mL | 25.2194 mL | |
| 10 mM | 0.5044 mL | 2.5219 mL | 5.0439 mL | 12.6097 mL | |
| 15 mM | 0.3363 mL | 1.6813 mL | 3.3626 mL | 8.4065 mL | |
| 20 mM | 0.2522 mL | 1.2610 mL | 2.5219 mL | 6.3049 mL | |
| 25 mM | 0.2018 mL | 1.0088 mL | 2.0176 mL | 5.0439 mL | |
| 30 mM | 0.1681 mL | 0.8406 mL | 1.6813 mL | 4.2032 mL | |
| 40 mM | 0.1261 mL | 0.6305 mL | 1.2610 mL | 3.1524 mL | |
| 50 mM | 0.1009 mL | 0.5044 mL | 1.0088 mL | 2.5219 mL | |
| 60 mM | 0.0841 mL | 0.4203 mL | 0.8406 mL | 2.1016 mL | |
| 80 mM | 0.0630 mL | 0.3152 mL | 0.6305 mL | 1.5762 mL | |
| 100 mM | 0.0504 mL | 0.2522 mL | 0.5044 mL | 1.2610 mL |
Methyl 4-(hydroxymethyl)bicyclo[2.2.2]octane-1-carboxylate Related Classifications
HY-W042100 Related Classifications
Powered by Bioz