2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 4-Hydroxyestrone

4-Hydroxyestrone  (Synonyms: 4-OHE1)

Cat. No.: HY-W009300 Purity: ≥99.0%
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4-Hydroxyestrone (4-OHE1), an estrone metabolite, has strong neuroprotective effect against oxidative neurotoxicity. 4-Hydroxyestrone increases cytoplasmic translocation of p53 resulting from SIRT1-mediated deacetylation of p53. 4-Hydroxyestrone has little estrogenic activity.

For research use only. We do not sell to patients.

4-Hydroxyestrone Chemical Structure

4-Hydroxyestrone Chemical Structure

CAS No. : 3131-23-5

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Based on 1 publication(s) in Google Scholar

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Description

4-Hydroxyestrone (4-OHE1), an estrone metabolite, has strong neuroprotective effect against oxidative neurotoxicity. 4-Hydroxyestrone increases cytoplasmic translocation of p53 resulting from SIRT1-mediated deacetylation of p53. 4-Hydroxyestrone has little estrogenic activity[1].

Molecular Weight

286.37

Formula

C18H22O3
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

OC(C=C1)=C(O)C(CC[C@@]2([H])[C@]3([H])CC4)=C1[C@@]2([H])CC[C@]3(C)C4=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥99.0%

COA (253 KB)

Handling Instructions (2659 KB)
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4-Hydroxyestrone Related Classifications

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Keywords:

4-Hydroxyestrone3131-23-54-OHE1Endogenous MetaboliteEstronemetaboliteneuroprotectiveoxidative neurotoxicityp53SIRT1deacetylationestrogenicInhibitorinhibitorinhibit

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