Propyl paraben-13C6
Based on 1 Customer Validation
Propyl paraben-13C6 (Propyl parahydroxybenzoate-13C6) is 13C labeled Propylparaben. Propylparaben (Propyl parahydroxybenzoate) is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben is commonly used in cosmetics, pharmaceuticals and foods. Propylparaben disrupts follicular growth and steroidogenic function by altering cell cycle, apoptosis and steroidogenic pathways. Propylparaben also reduced sperm count and motility in rats.
For research use only. We do not sell to patients.
- CAS No.: 2075718-26-0
- Formula: C413C6H12O3
- Molecular Weight:186.16
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2075718-26-0
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Unlabeled Cas 94-13-3
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Appearance Solid
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Molecular Weight 186.16
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Formula C413C6H12O3
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Color White to light brown
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SMILES
[H][13C]1=[13C]([13C]([H])=[13C]([13C](C(OCCC)=O)=[13C]1[H])[H])O
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Synonyms
Propyl parahydroxybenzoate-13C6; Propyl 4-hydroxybenzoate-13C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 125 mg/mL (671.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. S Oishi, et al. Effects of propyl paraben on the male reproductive system. Food Chem Toxicol. 2002 Dec;40(12):1807-13. [Content Brief]
[3]. Gal A, et, al. Propylparaben inhibits mouse cultured antral follicle growth, alters steroidogenesis, and upregulates levels of cell-cycle and apoptosis regulators. Reprod Toxicol. 2019 Oct;89:100-106. [Content Brief]
[4]. Final amended report on the safety assessment of Methylparaben, Ethylparaben, Propylparaben, Isopropylparaben, Butylparaben, Isobutylparaben, and Benzylparaben as used in cosmetic products. Int J Toxicol. 2008;27 Suppl 4:1-82. [Content Brief]
[5]. Ji X, et al. Propyl paraben inhibits voltage-dependent sodium channels and protects cardiomyocytes from ischemia-reperfusion injury. Life Sci. 2004 Apr 30;74(24):3043-52. [Content Brief]
[6]. Yan W, et al. Chronic exposure to propylparaben at the humanly relevant dose triggers ovarian aging in adult mice. Ecotoxicol Environ Saf. 2022 Apr 15;235:113432. [Content Brief]
[7]. Gal A, et al. Propylparaben inhibits mouse cultured antral follicle growth, alters steroidogenesis, and upregulates levels of cell-cycle and apoptosis regulators. Reprod Toxicol. 2019 Oct;89:100-106. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.3717 mL | 26.8586 mL | 53.7172 mL | 134.2931 mL |
| 5 mM | 1.0743 mL | 5.3717 mL | 10.7434 mL | 26.8586 mL | |
| 10 mM | 0.5372 mL | 2.6859 mL | 5.3717 mL | 13.4293 mL | |
| 15 mM | 0.3581 mL | 1.7906 mL | 3.5811 mL | 8.9529 mL | |
| 20 mM | 0.2686 mL | 1.3429 mL | 2.6859 mL | 6.7147 mL | |
| 25 mM | 0.2149 mL | 1.0743 mL | 2.1487 mL | 5.3717 mL | |
| 30 mM | 0.1791 mL | 0.8953 mL | 1.7906 mL | 4.4764 mL | |
| 40 mM | 0.1343 mL | 0.6715 mL | 1.3429 mL | 3.3573 mL | |
| 50 mM | 0.1074 mL | 0.5372 mL | 1.0743 mL | 2.6859 mL | |
| 60 mM | 0.0895 mL | 0.4476 mL | 0.8953 mL | 2.2382 mL | |
| 80 mM | 0.0671 mL | 0.3357 mL | 0.6715 mL | 1.6787 mL | |
| 100 mM | 0.0537 mL | 0.2686 mL | 0.5372 mL | 1.3429 mL |
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