Carvedilol metabolite 4-Hydroxyphenyl Carvedilol
4-Hydroxyphenyl Carvedilol, a metabolite of Carvedilol, is an active metabolite of Carvedilol (HY-B0006) and is produced via CYP2D6-mediated oxidation.
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- Pureza: 98.42%
- No. CAS: 142227-49-4
- Fòrmula: C24H26N2O5
- Peso molecular:422.47
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Chemical Information
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Actividad biológica
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CYP2D6 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
10.4 μM
Compound: 3
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Inhibition of RyR2 R4496C mutant-mediated store overload-induced calcium release in HEK293 cells assessed as reduction in amplitude of spontaneous calcium oscillations by fura-2 AM dye based fluorescence assay
Inhibition of RyR2 R4496C mutant-mediated store overload-induced calcium release in HEK293 cells assessed as reduction in amplitude of spontaneous calcium oscillations by fura-2 AM dye based fluorescence assay
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[PMID: 26584883] |
4-Hydroxyphenyl Carvedilol, a metabolite of Carvedilol, is an active metabolite of Carvedilol (HY-B0006) and is formed via CYP2D6-mediated oxidation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 142227-49-4
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Appearance Solid
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Peso molecular 422.47
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Fòrmula C24H26N2O5
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Color White to off-white
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SMILES
OC1=CC=C(OCCNCC(O)COC2=CC=CC(N3)=C2C4=C3C=CC=C4)C(OC)=C1
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Synonyms
4-Hydroxyphenyl Carvedilol; 4-Hydroxycarvedilol
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
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Ficha de datos (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
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- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
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Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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