1. Recombinant Proteins
  2. Receptor Proteins
  3. G-Protein-Coupled Receptors

G-Protein-Coupled Receptors

G Protein-Coupled Receptors (GPCRs), also called 7TM receptors, are the largest and most important integral membrane protein families, which mediate cellular responses to most hormones, metabolites, cytokines, and neurotransmitters, and therefore serve as “fruitful targets” for drug discovery. G Protein Coupled Receptors (GPCRs) perceive many extracellular signals and transduce them to heterotrimeric G proteins, which further transduce these signals intracellular to appropriate downstream effectors and thereby play an important role in various signaling pathways. GPCRs are categorized into six classes based on sequence and function: rhodopsin-like receptors (family A), secretin-like (family B), glutamate (family C), fungal mating pheromone receptors (Class D), cAMP receptors (Class E) and frizzled/smoothened (Class F). GPCRs in vertebrates are commonly divided in to rhodopsin (family A), secretin (family B), glutamate (family C), adhesion and Frizzled/Taste2, based on an alternative classification system (GRAFS).

Cat. No. Product Name / Synonyms Species Source
  • HY-P70352
    GLP1R Protein, Human (HEK 293, Fc)

    rHuGlucagon-like peptide 1 receptor/GLP1R, Fc; Glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R

    Human HEK293
  • HY-P71244
    PTH1R Protein, Human (HEK 293, His)

    Parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHrP type I receptor; PTH/PTHr receptor; Parathyroid hormone 1 receptor; PTH1 receptor; PTH1R

    Human HEK293
    PTH1R Protein, Human (HEK 293, His) is a recombinant PTH1R protein with a His-Flag. PTH1R plays an important role in skeletal development and homeostasis.
  • HY-P70210
    Frizzled-1 Protein, Mouse (HEK293, Fc)

    rMuFrizzled-1/Fz-1, Fc; Frizzled-1; Fz-1; mFz1; Fzd1; Frizzled homolog 1

    Mouse HEK 293
  • HY-P70915
    Frizzled-8 Protein, Human (HEK 293, His)

    frizzled 8; frizzled family receptor 8; Frizzled8; Frizzled-8; FZ-8; FZD8; hFZ8

    Human HEK293
  • HY-P70918
    FZD2 Protein, Mouse (HEK 293, Fc)

    Frizzled-2; Fz-2; mFz2; Fzd2; frizzled (Drosophila) homolog 2

    Mouse HEK293
  • HY-P71730
    EDNRA Protein, Human (P.pastoris, His)

    Ednra; ET A; ET-A; ETA; ETA R; ETA-R; ETAR; ETRA; G protein coupled receptor; hET AR; hET-AR; MFDA

    Human P. pastoris
  • HY-P72138
    CHRM1 Protein, Rat (His)

    Chrm1; Chrm-1Muscarinic acetylcholine receptor M1

    Rat E. coli
  • HY-P72159
    CXCR4 Protein, Human (His-SUMO)

    C-X-C chemokine receptor type 4; CD184; CD184 antigen; Chemokine C X C motif; receptor 4; Chemokine CXC Motif Receptor 4; CXC-R4; CXCR-4; CXCR4; CXCR4_HUMAN; D2S201E; FB22; Fusin; HM89; HSY3RR; LAP 3; LAP3; LCR1; LESTR; Leukocyte derived seven transmembrane domain receptor; Leukocyte-derived seven transmembrane domain receptor; Lipopolysaccharide associated protein 3; Neuropeptide Y receptor Y3; NPY3R; NPYR; NPYRL; NPYY3; NPYY3R; Probable G protein coupled receptor lcr1 homolog; SDF 1 receptor; SDF-1 receptor; SEVEN-TRANSMEMBRANE-SEGMENT RECEPTOR; Stromal cell derived factor 1 receptor; Stromal cell-derived factor 1 receptor; WHIM; WHIMS

    Human E. coli
  • HY-P72160
    CXCR4 Protein, Human (GST)

    C-X-C chemokine receptor type 4; CD184; CD184 antigen; Chemokine C X C motif; receptor 4; Chemokine CXC Motif Receptor 4; CXC-R4; CXCR-4; CXCR4; CXCR4_HUMAN; D2S201E; FB22; Fusin; HM89; HSY3RR; LAP 3; LAP3; LCR1; LESTR; Leukocyte derived seven transmembrane domain receptor; Leukocyte-derived seven transmembrane domain receptor; Lipopolysaccharide associated protein 3; Neuropeptide Y receptor Y3; NPY3R; NPYR; NPYRL; NPYY3; NPYY3R; Probable G protein coupled receptor lcr1 homolog; SDF 1 receptor; SDF-1 receptor; SEVEN-TRANSMEMBRANE-SEGMENT RECEPTOR; Stromal cell derived factor 1 receptor; Stromal cell-derived factor 1 receptor; WHIM; WHIMS

    Human E. coli
  • HY-P72198
    FSHR Protein, Human (His)

    Follicle stimulating hormone receptor; Follicle stimulating hormone receptor isoform 1; Follicle-stimulating hormone receptor; Follitropin receptor; FSH receptor; FSH-R; Fshr; FSHR_HUMAN; FSHRO; LGR1; MGC141667; MGC141668; ODG1; ovarian dysgenesis 1

    Human E. coli
  • HY-P72206
    GLP1R Protein, Mouse (His-SUMO)

    Glp1r; Glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R; GLP-1R

    Mouse E. coli
  • HY-P72372
    Frizzled-8 Protein, Human (Biotinylated, HEK 293, His-Avi)

    frizzled family receptor 8; Frizzled8; Frizzled-8; FZ-8; FZD8; hFZ8

    Human HEK293
  • HY-P72674
    CXCR4 Protein, Human (HEK 293, Fc)

    C-X-C chemokine receptor type 4; CXC-R4; LESTR; LAP-3; NPYRL; CD184; SDF-1 receptor

    Human HEK293
  • HY-P74134
    Frizzled-6 Protein, Human (HEK293, His)

    Frizzled homolog 6 (Drosophila); Frizzled-6; fz-6; FZD6

    Human HEK293
  • HY-P74135
    Frizzled-6 Protein, Human (HEK293, Fc)

    Frizzled homolog 6 (Drosophila); Frizzled-6; fz-6; FZD6

    Human HEK293
  • HY-P74136
    Frizzled-5 Protein, Mouse (CHO, Fc)

    Frizzled-5; Fz-5; mFz5; Fzd5

    Mouse CHO
  • HY-P74137
    Frizzled-5 Protein, Human (HEK293, His-Fc)

    C2orf31; Frizzled homolog 5 (Drosophila); Frizzled-5; FZ-5; FZD5

    Human HEK293
  • HY-P74138
    Frizzled-5 Protein, Human (HEK293, His)

    C2orf31; Frizzled homolog 5 (Drosophila); Frizzled-5; FZ-5; FZD5

    Human HEK293
  • HY-P74139
    Frizzled-5 Protein, Human (HEK293, Fc)

    C2orf31; Frizzled homolog 5 (Drosophila); Frizzled-5; FZ-5; FZD5

    Human HEK293
  • HY-P74140
    Frizzled-4/CD344 Protein, Human (HEK293, His)

    CD344 antigen; CD344; EVR1; FEVR; Frizzled-4; Fz-4; FZD4

    Human HEK293
Cat. No. Product Name Effect Purity