GPR35 agonist 1
Based on 1 Customer Validation
GPR35 agonist 1 (compound 50) is a potent and specific G protein-coupled receptor-35 (GPR35)/CXCR8 agonist with an EC50 of 5.8 nM, displays good agentgability.
For research use only. We do not sell to patients.
- Purity: 99.89%
- CAS No.: 2079880-92-3
- Formula: C10H4BrN5O5
- Molecular Weight:354.07
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
EC50: 5.8 nM (GPR35/CXCR8)[1]
Chemical Information
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CAS No. 2079880-92-3
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Appearance Solid
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Molecular Weight 354.07
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Formula C10H4BrN5O5
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Color Light yellow to yellow
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SMILES
O=C1C(C2=NN=NN2)=CC3=C(O1)C([N+]([O-])=O)=C(O)C(Br)=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (141.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8243 mL | 14.1215 mL | 28.2430 mL | 70.6075 mL |
| 5 mM | 0.5649 mL | 2.8243 mL | 5.6486 mL | 14.1215 mL | |
| 10 mM | 0.2824 mL | 1.4122 mL | 2.8243 mL | 7.0608 mL | |
| 15 mM | 0.1883 mL | 0.9414 mL | 1.8829 mL | 4.7072 mL | |
| 20 mM | 0.1412 mL | 0.7061 mL | 1.4122 mL | 3.5304 mL | |
| 25 mM | 0.1130 mL | 0.5649 mL | 1.1297 mL | 2.8243 mL | |
| 30 mM | 0.0941 mL | 0.4707 mL | 0.9414 mL | 2.3536 mL | |
| 40 mM | 0.0706 mL | 0.3530 mL | 0.7061 mL | 1.7652 mL | |
| 50 mM | 0.0565 mL | 0.2824 mL | 0.5649 mL | 1.4122 mL | |
| 60 mM | 0.0471 mL | 0.2354 mL | 0.4707 mL | 1.1768 mL | |
| 80 mM | 0.0353 mL | 0.1765 mL | 0.3530 mL | 0.8826 mL | |
| 100 mM | 0.0282 mL | 0.1412 mL | 0.2824 mL | 0.7061 mL |
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