2. GPCR/G Protein
  3. G Protein-coupled Receptor Kinase (GRK)
  4. GRK2i

GRK2i is a Gβγ-inhibitory peptide that selectively prevents Gβγ-mediated signaling. GRK2i corresponds to the Gβγ-binding domain of GRK2 (G-protein-coupled receptor kinase 2).

For research use only. We do not sell to patients.

Custom Peptide Synthesis

GRK2i Chemical Structure

GRK2i Chemical Structure

CAS No. : 148505-03-7

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GRK2i Related Antibodies

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Description

GRK2i is a Gβγ-inhibitory peptide that selectively prevents Gβγ-mediated signaling. GRK2i corresponds to the Gβγ-binding domain of GRK2 (G-protein-coupled receptor kinase 2)[1].

IC50 & Target

Gβγ
In Vitro

GRK2i (5 μM) inhibits neurite formation, disrupts microtubules, and induces neurite damag in PC12 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

GRK2i Related Antibodies
Molecular Weight

3484.08

Formula

C153H256N50O41S
CAS No.
Sequence Shortening

WKKELRDAYREAQQLVQRVPKMKNKPRS
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GRK2i Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GRK2i148505-03-7G Protein-coupled Receptor Kinase (GRK)GRK2polypeptideGβγactivationInhibitorinhibitorinhibit

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