GRL018-21
Based on 1 Customer Validation
GRL018-21 is a potent and highly selective G protein-coupled receptor kinase 5 (GRK5) inhibitor with an IC50 value of 10 nM.
For research use only. We do not sell to patients.
- Purity: 96.91%
- CAS No.: 3061801-07-5
- Formula: C30H25FN4O5
- Molecular Weight:540.54
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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GPCR/G Protein Compound Library
HY-L006
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Kinase Inhibitor Library
HY-L009
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Covalent Screening Library
HY-L036
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Anti-Cardiovascular Disease Compound Library
HY-L046
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Antihypertensive Compound Library
HY-L145
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Membrane Protein-targeted Compound Library
HY-L149
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Highly Selective Inhibitors Library
HY-L158
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Serine/Threonine Kinase Inhibitor Library
HY-L164
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MCE Bioactive Compound Library
HY-L001V
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Covalent Screening Library Plus
HY-L036P
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Protein Kinase Compound Library
HY-L196
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High-Throughput Bioactive Compound Library
HY-L205
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Posttranslational Modification Library
HY-L226
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Lactylation Compound Library
HY-L249
Biological Activity
Chemical Information
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CAS No. 3061801-07-5
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Appearance Solid
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Molecular Weight 540.54
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Formula C30H25FN4O5
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Color Orange to red
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SMILES
FC1=CC=C([C@@H](C)NC(C2=CC=C(NC(/C3=C\C4=C(C)C(NC(C(C5=CC=CO5)=O)=O)=C(C)N4)=O)C3=C2)=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 35 mg/mL (64.75 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8500 mL | 9.2500 mL | 18.5000 mL | 46.2500 mL |
| 5 mM | 0.3700 mL | 1.8500 mL | 3.7000 mL | 9.2500 mL | |
| 10 mM | 0.1850 mL | 0.9250 mL | 1.8500 mL | 4.6250 mL | |
| 15 mM | 0.1233 mL | 0.6167 mL | 1.2333 mL | 3.0833 mL | |
| 20 mM | 0.0925 mL | 0.4625 mL | 0.9250 mL | 2.3125 mL | |
| 25 mM | 0.0740 mL | 0.3700 mL | 0.7400 mL | 1.8500 mL | |
| 30 mM | 0.0617 mL | 0.3083 mL | 0.6167 mL | 1.5417 mL | |
| 40 mM | 0.0463 mL | 0.2313 mL | 0.4625 mL | 1.1563 mL | |
| 50 mM | 0.0370 mL | 0.1850 mL | 0.3700 mL | 0.9250 mL | |
| 60 mM | 0.0308 mL | 0.1542 mL | 0.3083 mL | 0.7708 mL |
GRL018-21 Related Classifications
HY-149720 Related Classifications
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