GR-11-1
Based on 1 Customer Validation
GR-11-1 is a GRK2 substrate for phosphorylation. GR-11-1 exhibits lower sensitivity and affinity for G protein-coupled receptor kinase 2.
For research use only. We do not sell to patients.
- Purity: 98.71%
- Formula: C61H91N15O28S2
- Molecular Weight:1546.59
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
GR-11-1 (50 μM; 60 min at 30 °C) functions as a substrate for recombinant human GRK2 (expressed in insect cells) with a Km of 33.9 μM and a Vmax of 0.35 pmol/min/mg, and exhibits low phosphorylation by recombinant human GRK5[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 1546.59
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Formula C61H91N15O28S2
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Color White to off-white
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Sequence
Asp-Glu-Met-Glu-Phe-Thr-Glu-Ala-Glu-Ser-Asn-Met-Asn
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Sequence Shortening
DEMEFTEAESNMN
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 25 mg/mL (16.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.6466 mL | 3.2329 mL | 6.4658 mL | 16.1646 mL |
| 5 mM | 0.1293 mL | 0.6466 mL | 1.2932 mL | 3.2329 mL | |
| 10 mM | 0.0647 mL | 0.3233 mL | 0.6466 mL | 1.6165 mL | |
| 15 mM | 0.0431 mL | 0.2155 mL | 0.4311 mL | 1.0776 mL |
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