PSB-16434
PSB-16434 is a selective G protein-coupled receptor 84 (GPR84) agonist. PSB-16434 is promising for research of inflammatory diseases, metabolic disorders, and immune regulation.
For research use only. We do not sell to patients.
- CAS No.: 2189700-02-3
- Formula: C12H12ClN3O2
- Molecular Weight:265.70
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | EC50 |
522 nM
Compound: 37
|
Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as beta-arrestin 2 recruitment measured after 90 mins by beta-galactosidase based PathHunter assay
Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as beta-arrestin 2 recruitment measured after 90 mins by beta-galactosidase based PathHunter assay
|
[PMID: 31721581] |
Chemical Information
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CAS No. 2189700-02-3
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Molecular Weight 265.70
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Formula C12H12ClN3O2
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SMILES
O=C1C=C(NCCC2=CC=C(C=C2)Cl)NC(N1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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