MRGPRX1 agonist 4
MRGPRX1 agonist 4 (compound 1t) is a potent and orally active Mas-related G protein-coupled receptor X1 (MRGPRX1) positive allosteric modulator with an EC50 value of 0.1 μM. MRGPRX1 agonist 4 has good metabolic stability and oral bioavailability. MRGPRX1 agonist 4 can reduce behavioral heat hypersensitivity in a neuropathic pain model humanized MRGPRX1 mice. MRGPRX1 agonist 4 can be used for researching neuropathic pain.
For research use only. We do not sell to patients.
- CAS No.: 2764889-60-1
- Formula: C23H17Cl2F3N2O2S
- Molecular Weight:513.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
EC50: 0.1 μM (MRGPRX1)[1]
Chemical Information
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CAS No. 2764889-60-1
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Molecular Weight 513.36
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Formula C23H17Cl2F3N2O2S
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SMILES
CC(C)(C1=C(C2=CC=C(C(Cl)=C2)Cl)C3=C(N=CN=C3OC4=C(C=CC=C4)OC(F)(F)F)S1)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MRGPRX1 agonist 4 Related Classifications
HY-143880 Related Classifications
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