(2S)-OMPT triethylamine, in ethanol:chloroform (1:1), 98%
Based on 1 Customer Validation
(2S)-OMPT (triethylamine), in ethanol:chloroform (1:1), 98%, Lysophosphatidic acid analogue, is a LPA3 G-protein-coupled receptor agonist. (2S)-OMPT (triethylamine), in ethanol:chloroform (1:1), 98% selectively activates LPA3 G-protein-coupled receptor to trigger downstream cellular signaling events. (2S)-OMPT (triethylamine), in ethanol:chloroform (1:1), 98% induces calcium, IL-6 release in cancer cells and activates MAPK and Akt signaling pathways. (2S)-OMPT (triethylamine), in ethanol:chloroform (1:1), 98% can be used for the research of ovarian cancer.
For research use only. We do not sell to patients.
- Purity : 99.0%
- CAS No.: 1217471-69-6
- Formula: C34H73N2O6PS
- Molecular Weight:668.99
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Storage:
Solution, -20°C, 2 years
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
IL-6 |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK-293T | EC50 |
276 nM
Compound: 9, OMPT
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Agonist activity at human LPA3 receptor transfected in HEK293T cells after 30 mins by GTP[gamma-35S] binding assay
Agonist activity at human LPA3 receptor transfected in HEK293T cells after 30 mins by GTP[gamma-35S] binding assay
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10.1039/C4MD00333K |
In Vitro
(2S)-OMPT (0.001-10000 nM) (triethylamine), in ethanol:chloroform (1:1), 98% induces calcium release in human ovarian cancer OVCAR3 cells with an EC50 of 9.0 nM[1].
(2S)-OMPT (0.01-1 μM) (triethylamine), in ethanol:chloroform (1:1), 98% activates Akt and MAPK phosphorylation in human ovarian cancer OVCAR3 cells[1].
(2S)-OMPT (0.01-10 μM) (triethylamine), in ethanol:chloroform (1:1), 98% induces IL-6 release in human ovarian cancer OVCAR3 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1217471-69-6
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Appearance Liquid
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Molecular Weight 668.99
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Formula C34H73N2O6PS
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Color Colorless to light yellow
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SMILES
O=C(CCCCCCC/C=C\CCCCCCCC)OC[C@@H](COP(O)(S)=O)OC.CCN(CC)CC.CCN(CC)CC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, 2 years
Purity & Documentation
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Data Sheet (264 KB)
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SDS (698 KB)
- English - EN (698 KB)
- Français - FR (698 KB)
- Deutsch - DE (698 KB)
- Norwegian - NO (698 KB)
- Español - ES (698 KB)
- Swedish - SV (698 KB)
- Italian - IT (698 KB)
- Korean - KR (698 KB)
- Portuguese - PT (698 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(2S)-OMPT triethylamine, in ethanol:chloroform (1:1), 98% Related Classifications
HY-120967 Related Classifications
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