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CID 1375606 

Cat. No.: HY-114146 Purity: 99.69%
Handling Instructions

CID 1375606 is a surrogate agonist of orphan G protein-coupled receptor GPR27.

For research use only. We do not sell to patients.

CID 1375606 Chemical Structure

CID 1375606 Chemical Structure

CAS No. : 313493-80-0

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 77 In-stock
Estimated Time of Arrival: December 31
5 mg USD 70 In-stock
Estimated Time of Arrival: December 31
10 mg USD 120 In-stock
Estimated Time of Arrival: December 31
25 mg USD 240 In-stock
Estimated Time of Arrival: December 31
50 mg USD 420 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Description

CID 1375606 is a surrogate agonist of orphan G protein-coupled receptor GPR27.

IC50 & Target

GPR 27[1].

In Vitro

CID 1375606 is a GPR27-specific surrogate agonist. GPR27 is characterized by a high level of conservation among vertebrates and a predominant expression in the central nervous system. In addition, it has recently been linked to insulin secretion[1].

Solvent & Solubility
In Vitro: 

DMSO : 53.33 mg/mL (138.43 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5958 mL 12.9789 mL 25.9578 mL
5 mM 0.5192 mL 2.5958 mL 5.1916 mL
10 mM 0.2596 mL 1.2979 mL 2.5958 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: 2.67 mg/mL (6.93 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.67 mg/mL (6.93 mM); Clear solution

References
Molecular Weight

385.24

Formula

C₂₀H₁₄Cl₂N₂O₂

CAS No.

313493-80-0

SMILES

O=C(NC1=CC=C(C(NC2=CC=CC=C2)=O)C=C1)C3=CC=C(Cl)C=C3Cl

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
CID 1375606
Cat. No.:
HY-114146
Quantity:

CID 1375606

Cat. No.: HY-114146