[Lys8, Lys9]-Neurotensin (8-13)
Based on 1 Customer Validation
[Lys8, Lys9]-Neurotensin (8-13) (JMV438), a Neurotensin analog, exerts its analgesic effects through activation of the G protein-coupled receptors NTS1 and NTS2, with Ki values of 0.33 nM and 0.95 nM for hNTS1 and hNTS2 receptors, respectively.
For research use only. We do not sell to patients.
- Purity : 99.95%
- CAS No.: 139026-64-5
- Formula: C38H64N8O8
- Molecular Weight:761.00
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Storage:
Sealed storage, away from moisture and light, under nitrogen.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Biological Activity
Description
Chemical Information
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CAS No. 139026-64-5
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Appearance Solid
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Molecular Weight 761.00
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Formula C38H64N8O8
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Color White to off-white
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Synonyms
JMV438
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Sequence Shortening
KKPYIL
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture and light, under nitrogen
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Solvent & Solubility
In Vitro:
H2O : 100 mg/mL (131.41 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.3141 mL | 6.5703 mL | 13.1406 mL | 32.8515 mL |
| 5 mM | 0.2628 mL | 1.3141 mL | 2.6281 mL | 6.5703 mL | |
| 10 mM | 0.1314 mL | 0.6570 mL | 1.3141 mL | 3.2852 mL | |
| 15 mM | 0.0876 mL | 0.4380 mL | 0.8760 mL | 2.1901 mL | |
| 20 mM | 0.0657 mL | 0.3285 mL | 0.6570 mL | 1.6426 mL | |
| 25 mM | 0.0526 mL | 0.2628 mL | 0.5256 mL | 1.3141 mL | |
| 30 mM | 0.0438 mL | 0.2190 mL | 0.4380 mL | 1.0951 mL | |
| 40 mM | 0.0329 mL | 0.1643 mL | 0.3285 mL | 0.8213 mL | |
| 50 mM | 0.0263 mL | 0.1314 mL | 0.2628 mL | 0.6570 mL | |
| 60 mM | 0.0219 mL | 0.1095 mL | 0.2190 mL | 0.5475 mL | |
| 80 mM | 0.0164 mL | 0.0821 mL | 0.1643 mL | 0.4106 mL | |
| 100 mM | 0.0131 mL | 0.0657 mL | 0.1314 mL | 0.3285 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.