MrgprX2-IN-2
MrgprX2-IN-2 (Compound example 12) is a selective Mas-related G-protein coupled receptor X2 (MRGPRX2) antagonist. MrgprX2-IN-2 blocks IgE-independent immune responses by inhibiting MRGPRX2-mediated mast cell degranulation and release of inflammatory mediators. MrgprX2-IN-2 is promising for research of pseudo-allergic reactions, chronic pruritus, and inflammatory diseases.
For research use only. We do not sell to patients.
- CAS No.: 2792205-87-7
- Formula: C20H19ClF6N6O
- Molecular Weight:508.85
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2792205-87-7
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Molecular Weight 508.85
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Formula C20H19ClF6N6O
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SMILES
O=C(N[C@H]1CC[C@@H](NC2=CC=CC3=NC(C(F)(F)F)=CN23)CC1)C4=CN(CC(F)(F)F)N=C4Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)