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Pathways Recommended:	Antibody-drug Conjugate/ADC Related

Results for "

antibody response

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (1) Antibody-Drug Conjugates (ADCs) (2) Aminoacyl-tRNA Synthetase (1) Amyloid-β (1) Apoptosis (3) Bacterial (4) Biochemical Assay Reagents (12) Btk (1) c-Fms (2) c-Met/HGFR (1) C-type Lectin-like Receptors (CTLRs) (1) CD2 (1) CD20 (1) CD276/B7-H3 (3) CD28 (2) CD3 (5) CD38 (1) CD44 (1) CD47 (1) Collagen (1) Complement System (1) CTLA-4 (2) CXCR (4) Dengue Virus (2) DNA/RNA Synthesis (1) Drug Intermediate (1) Drug Metabolite (1) Drug-Linker Conjugates for ADC (1) EAAT (1) EBV (1) EGFR (1) Endogenous Metabolite (4) Fc Receptor (FcR) (2) FGFR (1) FLT3 (1) Fluorescent Dye (1) Galectin (1) Glycosidase (2) HBV (1) HIF/HIF Prolyl-Hydroxylase (1) IFNAR (3) IMPDH (1) Influenza Virus (1) Integrin (1) Interleukin Related (23) JNK (1) LAG-3 (1) LDLR (1) Leukotriene Receptor (1) Liposome (1) MHC (6) NF-κB (7) NO Synthase (2) Notch (2) NTPDase (1) Orexin Receptor (OX Receptor) (2) Orthopoxvirus (1) p38 MAPK (1) PD-1/PD-L1 (13) Peptide-Drug Conjugates (PDCs) (1) Phosphatase (1) Phosphodiesterase (PDE) (1) PKC (1) Radionuclide-Drug Conjugates (RDCs) (1) Reactive Oxygen Species (ROS) (1) Reference Standards (1) SARS-CoV (4) Sirtuin (1) STAT (3) STING (3) Tau Protein (1) TGF-beta/Smad (1) Tim3 (2) TNF Receptor (21) Toll-like Receptor (TLR) (13) Topoisomerase (1) Transmembrane Glycoprotein (13) TREM receptor (1) VEGFR (2)
By Research Areas:	Cancer (75) Cardiovascular Disease (3) Infection (17) Inflammation/Immunology (101) Metabolic Disease (8) Neurological Disease (12)
Click Chemistry:	Azide (2)
Oligonucleotides:	CpG ODNs (3) Adjuvant (4)

151

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

104

Inhibitory Antibodies

Natural
Products

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: ADC Antibody Antibody-Drug Conjugates (ADCs) Antibody-Oligonucleotide Conjugates (AOCs) ADC Linker PROTAC-Linker Conjugates for PAC

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-153808A

Incomplete Freund's adjuvant (IFA) 4 Publications Verification	Bacterial	Inflammation/Immunology Cancer
Incomplete Freund's adjuvant (IFA) (Montanide ISA-51) is an immunoadjuvant emulsified with antigen by its discoverer Jules T. Freund. Incomplete Freund's adjuvant (IFA) does not contain inactivated tuberculosis bacilli and consists of petroleum jelly containing lanolin. Incomplete Freund's adjuvant (IFA) induces high antibody titers and long-lasting effector T cell responses with no long-term effects on collagen disease, tumors, or death. Complete Freund's adjuvant (CFA) (HY-153808) is another type of Freund's Adjuvant that stimulates a stronger immune response .

HY-P99901

Sibeprenlimab VIS649	SARS-CoV	Inflammation/Immunology Cancer
Sibeprenlimab (VIS649) is a humanized IgG2 monoclonal antibody which inhibits a proliferation-inducing ligand (APRIL). Sibeprenlimab suppresses pathogenic immunoglobulins (IgA and IgM), while preserving antibody responses to mRNA-based vaccines against SARS-COV-2. Sibeprenlimab reduces urinary protein-to-creatinine ratio (UPCR) and glomerular filtration rate (GFR). Sibeprenlimab is promising for the research of IgA nephropathy (IgAN) .

HY-NP133A

NP-KLH,Type II 4-Hydroxy-3-nitrophenylacetyl-Keyhole Limpet Hemocyanin,Type II	Biochemical Assay Reagents	Inflammation/Immunology
NP-KLH,Type II is a complex formed by 4-Hydroxy-3-nitrophenylacetyl (NP, a hapten) with Keyhole Limpet Hemocyanin (KLH, a carrier protein). NP-KLH,Type II can induce specific humoral immune responses and NP-specific antibodies production. NP-KLH,Type II can act as a specific antigen tool used for immunological experiments .

HY-P99361

Enavatuzumab PDL192; ABT-361; Anti-TNFRSF12A/TWEAKR/CD266 Reference antibody (enavatuzumab)	TNF Receptor	Cancer
Enavatuzumab (PDL192; ABT-361) is a humanized IgG1 monoclonal antibody targeting the receptor of TNF-like weak inducer of apoptosis (TWEAK). TWEAK (Fn14; TNFRSF12A), the natural ligand of the TWEAK receptor (TweakR), stimulates multiple cellular responses. Enavatuzumab induces tumor growth inhibition through direct TweakR signaling and antibody dependent cell-mediated cytotoxicity (ADCC). Enavatuzumab can actively recruits and activates myeloid effectors to kill tumor cells. Enavatuzumab inhibits the growth of various human TweakR-positive cancer cell lines and xenografts in vitro and in vivo .

HY-P99048

Sintilimab 1 Publications Verification IBI308	PD-1/PD-L1	Inflammation/Immunology Cancer
Sintilimab (IBI308) is a safe and effectivel humanized IgG4 monoclonal antibody that binds to PD-1 with a K_D value of 74 pM. Sintilimab blocks the interaction of PD-1 with its ligands (PD-L1 and PL-L2), consequently helping to restore the endogenous antitumour T-cell response. Sintilimab combined with prebiotics inhibits tumor volume and regulates immune cell subpopulation balance in lung adenocarcinoma mice. Sintilimab can be used for the research of classical Hodgkin's lymphoma, non-small cell lung cancer and oesophageal cancer .

HY-NP138

NP-OVAL (Ovalbumin)	Biochemical Assay Reagents	Inflammation/Immunology Cancer
NP-OVAL (Ovalbumin) is a complex formed by 4-Hydroxy-3-nitrophenylacetyl (NP, a hapten) with Ovalbumin (OVAL, a carrier protein). NP-OVAL (Ovalbumin) can induce specific immune responses and NP-specific antibodies production. NP-OVAL (Ovalbumin) can accelerate the construction of multiple myeloma models .

HY-P99126

Anti-Mouse/Human CD44 Antibody (IM7) 2 Publications Verification	Transmembrane Glycoprotein CD44	Inflammation/Immunology Cancer
Anti-Mouse/Human CD44 Antibody (IM7) is an anti-huamn and mouse CD44 IgG2b monoclonal antibody that recognizes a conserved epitope outside the HA-binding domain of the CD44 molecule. Anti-Mouse/Human CD44 Antibody (IM7) exerts a potent anti-inflammatory effect by inducing the shedding of cell surface CD44, significantly improving symptoms in mice with rheumatoid arthritis without affecting relevant immune responses. Anti-Mouse/Human CD44 Antibody (IM7) can be used for researches on inflammation conditions and cancer such as arthritis and osteosarcoma .

HY-P99389

Tesnatilimab JNJ-64304500; IPH-2301; NN-8555	C-type Lectin-like Receptors (CTLRs)	Inflammation/Immunology
Tesnatilimab (JNJ-64304500) is a human IgG4 monoclonal antibody targeting NKG2D, with a K_D value of 9.2 pM . Tesnatilimab blocks the binding of ligands to the NKG2D receptor, thereby inhibiting downstream proinflammatory cytokine, cytotoxic mediator signaling pathways and proinflammatory immune responses. Tesnatilimab is applicable to research related to Crohn's disease .

HY-P99044

Sabatolimab 1 Publications Verification MBG453	Tim3	Inflammation/Immunology
Sabatolimab (MBG453) is a high-affinity, humanized, IgG4 (S228P) antibody targeting TIM-3, an inhibitory receptor that regulates adaptive and innate immune responses. Sabatolimab is a potential immunosuppression agent that can target TIM-3 on immune and myeloid cells .

HY-P99199

Foralumab NI-0401	CD3	Inflammation/Immunology
Foralumab (NI-0401) is a potent, orally active human monoclonal antibody targeting the CD3. Foralumab modulates immune responses by human cells in NSG mice that were reconstituted with human hematopoietic stem cells .

HY-P99625

Frexalimab SAR441344; INX-021	TNF Receptor	Metabolic Disease Inflammation/Immunology
Frexalimab (SAR441344) is a second-generation monoclonal antibody targeting the CD40 ligand (CD40L) with a good safety profile. Frexalimab inhibits the binding between CD40 and CD40L to modulate immune response. Frexalimab is likely to help prevent the process of β-cell destruction. Frexalimab is proming for multiple sclerosis, lupus erythematosus, Sj gren’s syndrome and type I diabetes research .

HY-P99049

Sotigalimab APX005M; APX005M; EPI-0050	TNF Receptor	Inflammation/Immunology
Sotigalimab, a CD40 agonistic monoclonal antibody. Sotigalimab binds CD40 with high affinity and activates antigen-presenting cells, thereby stimulating cancer-specific T cell responses. Sotigalimab is mainly used in the study of metastatic pancreatic cancer and metastatic melanoma .

HY-P99683

Ladiratuzumab vedotin SGN-LIV1A	Antibody-Drug Conjugates (ADCs)	Cancer
Ladiratuzumab vedotin (SGN-LIV1A) is a LIV-1 targeting antibody drug conjugate (ADC) (IC₅₀: 5.6 nM for LIV-1). Ladiratuzumab vedotin consists of humanized IgG1 monoclonal antibody, MMAE and a protease-cleavable linker. Ladiratuzumab vedotin can drive immunogenic cell death (ICD) to elicit an immune response. Ladiratuzumab vedotin can be used for research of breast cancer .

HY-P99834

Crefmirlimab IAB22M2C; ImaginAb	Transmembrane Glycoprotein	Cancer
Crefmirlimab (IAB22M2C; ImaginAb) is a humanized CD8-specific single-domain antibody. Conjugation of Crefmirlimab with radioisotopes (e.g., ⁸⁹Zr) enables tumor immune infiltration assessment, autoimmune disease detection, and immunotherapy response monitoring. Crefmirlimab is applicable for cancer research .

HY-P990802

Anti-Mouse CD3ε Antibody (145-2C11)	CD3	Metabolic Disease Inflammation/Immunology
Anti-Mouse CD3ε Antibody (145-2C11) is an orally active anti-mouse CD3ε IgG1 monoclonal antibody. Anti-Mouse CD3ε Antibody (145-2C11) can inhibit the proliferation of effector T cells and improve the function of regulatory T cells (Tregs). Anti-Mouse CD3ε Antibody (145-2C11) relieves inflammatory response by inhibiting the production of pro-inflammatory cytokines and increasing the secretion of anti-inflammatory factors. Anti-Mouse CD3ε Antibody (145-2C11) can be used for researches on metabolic and immune system conditions such as diabetes and lupus. The recommend isotype control of Anti-Mouse CD3ε Antibody (145-2C11): Armenian hamster IgG, Isotype Control (HY-P990305) .

HY-128481

SB24011	STING	Inflammation/Immunology Cancer
SB24011 is a STING modulator and a TRIM29-STING protein-protein interaction inhibitor. SB24011 blocks TRIM29-induced K48-linked specific ubiquitination by binding to STING, thereby upregulating intracellular STING protein levels. SB24011 enhances inflammatory cytokine expression and STING-mediated immune responses, and exhibits abscopal antitumor activity that promotes tumor regression and activates T cell infiltration. When combined with STING agonists or anti-PD1 antibodies, SB24011 synergistically enhances antitumor responses. SB24011 is suitable for research related to colon cancer and melanoma .

HY-P99152

Muromonab Muromanab-CD3	CD3 Interleukin Related IFNAR	Inflammation/Immunology Cancer
Muromonab (Muromonab-CD3; OKT3) is a mouse monoclonal antibody targeting the CD3 antigen. Muromonab specifically binds to the CD3 antigen on the surface of human and higher primate T cells. Muromonab blocks the function of T cell receptors to recognize foreign antigens and inhibits T cell-mediated immune responses, including cell-mediated lymphocyte lysis and T cell proliferation responses. Muromonab can be used to study acute kidney, liver, heart and combined kidney-pancreas transplant rejection, and can also be used to study graft-versus-host disease in bone marrow transplant patients .

HY-P99259

Cabiralizumab FPA 008; Anti-Human CSF1R Recombinant antibody	c-Fms	Inflammation/Immunology Cancer
Cabiralizumab (FPA 008) is an anti-CSF1R monoclonal antibody (MAb). Cabiralizumab enhances T cell infiltration and antitumor T cell immune responses. Cabiralizumab inhibits the activation of osteoclasts and blocks bone destruction, and can be used in the research of rheumatoid arthritis (RA). Cabiralizumab can combine with Nivolumab (HY-P9903) for lung cancer research .

HY-P991267

CAN10	Interleukin Related	Inflammation/Immunology
CAN10 is is a humanized monoclonal antibody inhibitor targeting interleukin 1RAP (IL1RAP). CAN10 blocks IL-1, IL-33, and IL-36 signalling by targeting IL1RAP, preventing downstream proinflammatory and profibrotic responses. CAN10 reduces dermal and pulmonary fibrosis. CAN10 can be used for the research of immune system diseases, such as systemic sclerosis .

HY-164485

INI-4001	Toll-like Receptor (TLR) SARS-CoV	Infection
INI-4001 is a TLR7/8 agonist and vaccine adjuvant. INI-4001 regulates innate and adaptive immune responses by activating murine TLR7 and human TLR7/TLR8. INI-4001 enhances IgG and neutralizing antibody responses against Powassan virus (POWV), reduces viral loads in the brain, liver and spleen, provides complete protection against lethal POWV challenge, and skews immune responses toward a Th1 phenotype. When INI-4001 is used in combination with Al (OH)₃ and SARS-CoV-2 RBD antigen, it efficiently adsorbs to Al (OH)₃, promotes Th1 immunity and enhances SARS-CoV-2 neutralizing antibody responses. INI-4001 is applicable to research related to Powassan virus infection and COVID-19 .

HY-P990219

Anti-Mouse IL-2 Antibody (JES6-1A12)	Interleukin Related	Infection Inflammation/Immunology
Anti-Mouse IL-2 Antibody (JES6-1A12) is an anti-mouse IL-2 IgG1 monoclonal antibody. Anti-Mouse IL-2 Antibody (JES6-1A12) can inhibit Treg amplification and enhance Th1 response. Anti-Mouse IL-2 Antibody (JES6-1A12) can form a complex with IL-2 for experimentation. Anti-Mouse IL-2 Antibody (JES6-1A12) can be used for research on infection conditions such as malaria .

HY-P990680

Anti-Mouse CD40 Antibody (FGK4.5/FGK45)	Transmembrane Glycoprotein TNF Receptor	Infection Inflammation/Immunology Cancer
Anti-Mouse CD40 Antibody (FGK4.5/FGK45) is an agonistic rat-derived IgG2a monoclonal antibody targeting mouse CD40. Anti-Mouse CD40 Antibody (FGK4.5/FGK45) enhances T cells responses, dendritic cells maturation and NK cells activation. Anti-Mouse CD40 Antibody (FGK4.5/FGK45) can be used for the researches of cancer, infection, inflammation and immunology, such as CT26 tumor, vesicular stomatitis virus (VSV) infection and transplantation .

HY-150726

ODN 1668 1 Publications Verification	Toll-like Receptor (TLR) Bacterial	Infection Neurological Disease Inflammation/Immunology
ODN 1668, a class B CpG ODN (oligodeoxynucleotide), is a TLR-9 agonist. ODN 1668 has strong immune regulatory properties, can enhance the level of antibody IgG2 subtype, promote the immune response of T cells and B cells, and can be used in the study of vaccine adjuvants. In addition, CpG ODN 1668 induces an antimicrobial immune response via a CaTLR9 dependent pathway in groupers. Sequence: 5'-tccatgacgttcctgatgct-3’ .

HY-150726C

ODN 1668 sodium 1 Publications Verification	Toll-like Receptor (TLR) Bacterial	Infection Neurological Disease Inflammation/Immunology
ODN 1668 sodium, a class B CpG ODN (oligodeoxynucleotide), is a TLR-9 agonist. ODN 1668 sodium has strong immune regulatory properties, can enhance the level of antibody IgG2 subtype, promote the immune response of T cells and B cells, and can be used in the study of vaccine adjuvants. In addition, CpG ODN 1668 sodium induces an antimicrobial immune response via a CaTLR9 dependent pathway in groupers. Sequence: 5'-tccatgacgttcctgatgct-3’ .

HY-P99793

Orticumab MLDL1278A	LDLR	Inflammation/Immunology
Orticumab (MLDL1278A) is an antibody targeting to oxidized or malondialdehyde-modified lipoprotein (LDL). Orticumab specifically inhibits oxidized low-density lipoproteins (oxLDL). Orticumab involves in modulation of autoimmune responses against oxLDL, improves atherosclerosis in animal model. Orticumab also can be used for research of psoriasis improvement .

HY-P990254

Anti-Mouse CXCR3/CD183 Antibody (CXCR3-173)	CXCR	Inflammation/Immunology Cancer
Anti-Mouse CXCR3/CD183 Antibody (CXCR3-173) is an anti-mouse CXCR3/CD183 IgG monoclonal antibody. Anti-Mouse CXCR3/CD183 Antibody (CXCR3-173) weakens the immune response by reducing the infiltration of CD4 ⁺ and CD8 ⁺ T cells. Anti-Mouse CXCR3/CD183 Antibody (CXCR3-173) significantly prolongs the survival time of heart or islet transplants in mice. Anti-Mouse CXCR3/CD183 Antibody (CXCR3-173) can be used for researches on immunology and cancer such as pancreatic cancer .

HY-P99845

Dazodalibep MEDI 4920; VIB 4920	TNF Receptor	Inflammation/Immunology
Dazodalibep (MEDI 4920; VIB 4920) is a non-antibody fusion protein that targets CD40L. Dazodalibep inhibits the co-stimulatory signals between immune cells (such as T cells, B cells, and antigen-presenting cells), thereby enabling the inhibition of a broader range of cellular and humoral responses. Dazodalibep can be used for research on rheumatoid arthritis and Sjögren's syndrome .

HY-P99414

Prezalumab AMG 557	Transmembrane Glycoprotein Interleukin Related	Inflammation/Immunology
Prezalumab (AMG 557) is a humanized IgG2 monoclonal antibody targeting ICOSL. Prezalumab inhibits T cell activation and related immune responses by binding to ICOSL and blocking the interaction between ICOS and ICOSL. Prezalumab can be used in the research of autoimmune diseases and inflammatory diseases such as systemic lupus erythematosus. Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002) .

HY-P99661

Inbakicept 2 Publications Verification	Interleukin Related	Cancer
Inbakicept is a dimeric human IL-15 receptor alpha (IL-15 Ra) sushi domain/human IgG1 Fc fusion protein and is an IL-15 superagonist complex. Inbakicept is able to form complex N-803 (Nogapendekin alfa inbakicept) with the IL-15 antibody Nogapendekin alfa in a 1:2 ratio. N-803 mimics the function of IL-15 and amplifies anti-CD20 mAb-mediated NK cell responses and antibody-dependent cellular cytotoxicity (ADCC). N-803 also increases degranulation and IFNγ production in cells .

HY-P99031

Mavrilimumab CAM 3001	c-Fms	Cardiovascular Disease Inflammation/Immunology
Mavrilimumab (CAM 3001) is a monoclonal antibody that binds to the α subunit of the granulocyte-macrophage colony stimulating factor (GM-CSF) receptor and blocks intracellular signalling downstream of GM-CSF. GM-CSF might be a mediator of the hyperactive inflammatory response associated with respiratory failure and death .

HY-102090

B7/CD28 interaction inhibitor 1	CD28	Inflammation/Immunology
B7/CD28 interaction inhibitor 1 (copmound 6b) is a potent B7.1-CD28 interaction inhibitor with an IC₅₀ of 50 nM .

HY-P99744

Modakafusp alfa TAK-573	CD38	Inflammation/Immunology Cancer
Modakafusp alfa (TAK-573) is a humanized, *anti-CD38* IgG4 monoclonal antibody fused to 2 attenuated IFNα2b molecules, which delivers interferon-alpha to CD38-expressing cells. Modakafusp alfa has direct anti-proliferative activity on multiple myeloma (MM) cancer cells in vitro and induces robust and durable antitumor responses in MM xenograft tumor models. Modakafusp alfa in combination with anti-PD-1 antibodies induces immunomodulation and antitumor responses with good tolerance in mice .

HY-P99057

Varlilumab CDX-1127	TNF Receptor Transmembrane Glycoprotein	Inflammation/Immunology Cancer
Varlilumab (CDX-1127) is an agonist *anti-CD27* monoclonal antibody. Varlilumab can promote T cell expansion and activate the immune response. Varlilumab has anti-tumor activity and can be used in the research of hematological malignancies and solid tumors .

HY-P99872

Ecleralimab CSJ-117; NVP-CSJ117	Interleukin Related	Inflammation/Immunology
Ecleralimab (CSJ-117; NVP-CSJ117) is a Fab-IgG1-λ2 antibody targeting the thymic stromal lymphopoietin (TSLP). Ecleralimab significantly attenuates allergen-induced airway responses and inflammation. Ecleralimab can be used for the study of inhaled asthma .

HY-P99714

Lorigerlimab MGD019	PD-1/PD-L1 CTLA-4	Cancer
Lorigerlimab (MGD019) is a bispecific IgG4 dual-affinity re-targeting antibody (DART). Lorigerlimab can block PD-1 and CTLA-4, and improves T-cell responses. Lorigerlimab can be used for research of metastatic castration-resistant prostate cancer (mCRPC) .

HY-P99125

Anti-Mouse CD16/CD32 Antibody (2.4G2)	Fc Receptor (FcR)	Cardiovascular Disease Inflammation/Immunology
Anti-Mouse CD16/CD32 Antibody (2.4G2) is an anti-mouse CD16/CD32 IgG2b monoclonal antibody. Anti-Mouse CD16/CD32 Antibody (2.4G2) can block Fcγ receptor-mediated immune responses. Anti-Mouse CD16/CD32 Antibody (2.4G2) can block the combination of CD16 and FcγRs to reduce the production of foam cells. Anti-Mouse CD16/CD32 Antibody (2.4G2) can be used for researches on atherosclerosis and autoimmune hematological disorders .

HY-P991257

MK-1966 1 Publications Verification	Interleukin Related CXCR MHC	Cancer
MK-1966 is an anti-IL-10 antibody. MK-1966 inhibits secretion of cytokines from activated macrophages, production of CC and CXC chemokines, and a TH1 response, down-regulates MHC and costimulatory molecules on dendritic cells (DCs), and induces regulatory T cells. MK-1966 can be used for the research of cancer , such as gastric cancer .

HY-P990667

STX-100	Integrin TGF-beta/Smad	Inflammation/Immunology Cancer
STX-100 is a humanized monoclonal antibody targeting αVβ6 integrin. STX-100 specifically binds αVβ6 integrin, blocks latent TGF-β activation via latency-associated peptide (LAP) interaction prevention, and reduces profibrotic responses. STX-100 can be used for the research of idiopathic pulmonary fibrosis, and cancer .

HY-P99431

KY-1044 Alomfilimab; SAR 445256	CD28	Inflammation/Immunology Cancer
KY-1044 (Alomfilimab; SAR 445256) is a fully human IgG1 antibody targeting inducible costimulatory receptor (ICOS). KY-1044 depletes ICOS ^high cells via antibody-dependent cellular cytotoxicity (ADCC) through the engagement of FcgRIIIa. KY-1044 act as a costimulatory molecule on cells expressing lower ICOS levels, such as CD8 ⁺ T_Eff cells (through FcgR-dependent clustering). KY-1044 exploit the differential expression of ICOS on T-cell subtypes to improve the intratumoral immune contexture and restore an antitumor immune response .

HY-P99012

Clazakizumab	Interleukin Related SARS-CoV	Infection Inflammation/Immunology
Clazakizumab is a monoclonal antibody with high affinity and specificity for the IL-6 (interleukin-6) cytokine. Clazakizumab may be helpful in inhibiting the cytokine response to SARS-CoV-2 in COVID-19. Clazakizumab can be used for the research of psoriatic arthritis (PsA) and renal antibody-mediated rejection .

HY-P99257

Bleselumab ASKP 1240	TNF Receptor	Inflammation/Immunology
Bleselumab (ASKP 1240) is a human anti-CD40 monoclonal antibody (mAb). Bleselumab binds to human CD40 with high affinity (K_d: 0.24 nM). Bleselumab inhibits immune responses by blocking the interaction of CD40 with its ligand CD40L. Bleselumab prevents organ transplant rejection .

HY-P990782

Efzofitimod	Aminoacyl-tRNA Synthetase	Inflammation/Immunology
Efzofitimod is a splice variant of the aminoacyl-tRNA synthetase HARS1, which is fused with the Fc segment of a human antibody. Efzofitimod targets the neuronal phospholipid NRP2 (neuropilin-2) and has anti-inflammatory and immunomodulatory activities. Efzofitimod can downregulate the innate and adaptive immune responses in inflammatory disease states, suppressing indirect lung disease (ILD) .

HY-P990018

Boserolimab MK-5890	TNF Receptor NF-κB	Inflammation/Immunology Cancer
Boserolimab (MK-5890) is a humanized agonist monoclonal antibody that binds to CD27 to provide a costimulatory signal that enhances T-cell–mediated responses .

HY-P99409

Oregovomab Alt-2 monoclonal antibody; MAB-B43.13; Oregovamab	Transmembrane Glycoprotein	Cancer
Oregovomab (Alt-2 monoclonal antibody) is a murine mAb targeting CA125. Oregovomab induces cytotoxic immune response against CA125 expressing tumor cells .

HY-165084

L-a-Phosphatidylserine sodium Soy PS sodium	Liposome	Inflammation/Immunology
L-a-Phosphatidylserine sodium is an antigen targeting phosphatidylserine (PS) and can induce the production of polyclonal antibodies. L-a-Phosphatidylserine can trigger complement-dependent immune damage by binding to PS on the cell membrane surface. After L-a-Phosphatidylserine is recognized by antibodies, it activates the complement system, causing liposome membrane damage and content release, and then participates in the regulation of immune response and cell apoptosis signaling. L-a-Phosphatidylserine can be used in immunological research, such as antibody specificity analysis and complement activation mechanism research .

HY-113512

17-HDHA	Influenza Virus	Inflammation/Immunology
17-HDHA is a DHA-derived specialized proresolving mediator (SPM). 17-HDHA enhances the antibody-mediated immune response against influenza virus. 17-HDHA enhances the differentiation of B cells toward the CD27 ⁺ CD38 ⁺ antibody-secreting cell phenotype, thereby strongly increasing IgM and IgG production by activated B cells .

HY-159102

PVP-037.2	Toll-like Receptor (TLR)	Inflammation/Immunology
PVP-037.2 is a TLR7/8 agonist. PVP-037.2 can serve as an adjuvant to enhance vaccine-induced T_H1 type immune responses, increasing the production of antigen-specific antibodies IgG1 and IgG2c .

HY-P990175

Anti-Mouse OX40L/CD134L Antibody (RM134L)	Orexin Receptor (OX Receptor)	Inflammation/Immunology Cancer
Anti-Mouse OX40L/CD134L Antibody (RM134L) is an anti-mouse OX40L/CD134L IgG2b monoclonal antibody. Anti-Mouse OX40L/CD134L Antibody (RM134L) reduces immune response by inhibiting the OX40/OX40L signaling pathway. Anti-Mouse OX40L/CD134L Antibody (RM134L) can inhibit plasma cell differentiation and antibody secretion. Anti-Mouse OX40L/CD134L Antibody (RM134L) can prolong the survival time of cell transplantation by inhibiting CD4 ⁺ T cells. Anti-Mouse OX40L/CD134L Antibody (RM134L) can be used for researches on inflammation and cancer such as graft versus host disease (GVHD), allergic reaction, lupus nephritis and hepatocellular carcinoma (HCC) .

HY-P990294

Anti-Mouse CD106/VCAM-1 Antibody (M/K-2.7)	Transmembrane Glycoprotein STAT Collagen Reactive Oxygen Species (ROS) Interleukin Related	Cardiovascular Disease Inflammation/Immunology
Anti-Mouse CD106/VCAM-1 Antibody (M/K-2.7) is an anti-mouse CD106/VCAM-1 IgG1 monoclonal antibody. Anti-Mouse CD106/VCAM-1 Antibody (M/K-2.7) reduces inflammatory response and oxidative stress by lowering p-STAT3 and reactive oxygen species (ROS) levels. Anti-Mouse CD106/VCAM-1 Antibody (M/K-2.7) can alleviate cardiac inflammation and fibrosis by reducing the expression of collagen I and collagen III. Anti-Mouse CD106/VCAM-1 Antibody (M/K-2.7) can be used for research on cardiovascular conditions such as hypertensive heart condition and subretinal fibrosis .

HY-111782

8-Mercaptoguanosine 8-Thioguanosine	Toll-like Receptor (TLR)	Inflammation/Immunology
8-Mercaptoguanosine is an immunoadjuvant that affects the in vivo antibody response to the T-cell-independent antigen TNP-Ficoll. 8-Mercaptoguanosine enhances IgG1, IgG2, and IgG3 antibody responses, but has no effect on IgM antibody responses. 8-Mercaptoguanosine also enhances antibody responses to very weak antigens such as pneumococcal polysaccharide and restores antibody responses in immunodeficient xid mice that are non-reactive to TNP-Ficoll .

Cat. No.	Product Name	Type

HY-NP133A

NP-KLH,Type II 4-Hydroxy-3-nitrophenylacetyl-Keyhole Limpet Hemocyanin,Type II	Biochemical Assay Reagents
NP-KLH,Type II is a complex formed by 4-Hydroxy-3-nitrophenylacetyl (NP, a hapten) with Keyhole Limpet Hemocyanin (KLH, a carrier protein). NP-KLH,Type II can induce specific humoral immune responses and NP-specific antibodies production. NP-KLH,Type II can act as a specific antigen tool used for immunological experiments .

HY-NP138

NP-OVAL (Ovalbumin)	Biochemical Assay Reagents
NP-OVAL (Ovalbumin) is a complex formed by 4-Hydroxy-3-nitrophenylacetyl (NP, a hapten) with Ovalbumin (OVAL, a carrier protein). NP-OVAL (Ovalbumin) can induce specific immune responses and NP-specific antibodies production. NP-OVAL (Ovalbumin) can accelerate the construction of multiple myeloma models .

HY-W145481A

D-Galacto-D-mannan

Carob galactomannan

Biochemical Assay Reagents

D-Galacto-D-mannan (Carob galactomannan) is an orally active Dectin-2 agonist. D-Galacto-D-mannan exerts antioxidant activity against hydroxyl radical generation. D-Galacto-D-mannan activates Dectin-2 to trigger downstream signaling pathways, promote the expression of immunoregulatory molecules, coordinate innate and adaptive immune responses, and inhibit excessive inflammatory responses by upregulating the expression of Sirtuin 1. When used as a vaccine adjuvant, D-Galacto-D-mannan induces cellular and humoral immune responses, promotes IFNγ secretion, increases antibody levels and virus neutralization titers, and elevates the levels of immunoglobulin G and A. D-Galacto-D-mannan can serve as an adjuvant for foot-and-mouth disease vaccines, enhance the vaccine-mediated ability of hosts to defend against viral infection in mice, and reduce local side effects at the inoculation site in pigs. D-Galacto-D-mannan can be used in the research of inflammatory and immune diseases, such as foot-and-mouth disease .

HY-NP002H

Porcine Serum Albumin (globulin free)	Biochemical Assay Reagents
Porcine Serum Albumin (globulin free) is a serum albumin protein containing a flexible C-terminal region. Porcine Serum Albumin (globulin free) induces the production of anti-PSA IgG antibodies in rats and triggers severe immune responses upon secondary administration .

HY-154818

Bovine Serum Albumin, Acetylated

Ac-BSA

Biochemical Assay Reagents

Bovine Serum Albumin, Acetylated (Ac-BSA) is a polypeptide of known structure with strong antigenicity. Bovine Serum Albumin, Acetylated produced a significant immune response, validating the accuracy and reliability of the experimental method. Bovine Serum Albumin, Acetylated can be used as a positive control substance in ELISA or WB experiments, and can be used in experiments with acetylated lysine monoclonal or polyclonal antibodies. Bovine Serum Albumin, Acetylated also improves encapsulation efficiency at low concentrations of PLGA, a polymer for biopharmaceutical delivery with biocompatibility, degradability, and controlled release properties .

HY-153209G

Adjuvant-4 (GMP)	Biochemical Assay Reagents
Adjuvant-4 (GMP) is a GMP grade Adjuvant-4. Adjuvant-4 is a vaccine adjuvant that enhances antigen-specific antibody titers and cytotoxic T lymphocyte (CTL) responses . Adjuvant is generally an oil-in-water emulsifier of mineral oil and mannitol monooleate.

Cat. No.	Product Name	Target	Research Area

HY-P1240

MOG (35-55) mouse, rat Maximum Cited Publications 9 Publications Verification Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat	Endogenous Metabolite	Neurological Disease Inflammation/Immunology
MOG (35-55) mouse, rat (Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat) is a minor component of CNS myelin. MOG (35-55) mouse, rat has encephalitogenic activity and induces T cell proliferative. MOG (35-55) mouse, rat induces Th1 cytokine response as well as relatively high levels of IgG antibodies. MOG (35-55) mouse, rat produces a relapsing-remitting neurological disease with extensive plaque-like demyelination. MOG (35-55) mouse, rat (MOG (35-55)) can be used for experimental autoimmune encephalomyelitis (EAE) modeling .

HY-P1240A

MOG (35-55) TFA Maximum Cited Publications 9 Publications Verification Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA	Endogenous Metabolite	Neurological Disease Inflammation/Immunology
MOG (35-55) (MOG (35-55)) TFA is a minor component of CNS myelin. MOG (35-55) (TFA) has encephalitogenic activity and induces T cell proliferative. MOG (35-55) (TFA) induces Th1 cytokine response as well as relatively high levels of IgG antibodies. MOG (35-55) (TFA) produces a relapsing-remitting neurological disease with extensive plaque-like demyelination. MOG (35-55) (MOG (35-55)) TFA can be used for experimental autoimmune encephalomyelitis (EAE) modeling .

HY-P1240B

MOG (35-55) acetate Maximum Cited Publications 9 Publications Verification Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate	Peptides	Neurological Disease Inflammation/Immunology
MOG (35-55) (Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat) acetate is a minor component of CNS myelin. MOG (35-55) (acetate) has encephalitogenic activity and induces T cell proliferative. MOG (35-55) (acetate) induces Th1 cytokine response as well as relatively high levels of IgG antibodies. MOG (35-55) (acetate) produces a relapsing-remitting neurological disease with extensive plaque-like demyelination. MOG (35-55) (Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat) acetate can be used for experimental autoimmune encephalomyelitis (EAE) modeling .

HY-P10427

DV1	CXCR Dengue Virus	Neurological Disease Inflammation/Immunology Cancer
DV1 is a CXCR4 inhibitor with anti-proteolytic properties that specifically blocks the binding of SDF-1α to its receptor. DV1 inhibits the migration of breast cancer cells and enables the targeted delivery of avidin-PLGA nanoparticles to CXCR4-expressing cancer cells. DV1 not only effectively suppresses the progression of metastatic breast cancer in mouse models, but also preferentially accumulates in brain tumor tissues rather than normal brain tissues, showing potential for inhibiting intracranial tumor metastasis. As a humoral immune stimulant, DV1 induces the production of specific IgG, neutralizing antibodies and cellular immune responses, thereby providing the host with protection against lethal challenges. DV1 has been applied to studies on CXCR4-expressing cancers, glioblastoma, dengue fever and other related diseases .

HY-P10427A

DV1 TFA	CXCR Dengue Virus	Infection
DV1 TFA is a CXCR4 inhibitor with anti-proteolytic properties that specifically blocks the binding of SDF-1α to its receptor. DV1 TFA inhibits the migration of breast cancer cells and enables the targeted delivery of avidin-PLGA nanoparticles to CXCR4-expressing cancer cells. DV1 TFA not only effectively suppresses the progression of metastatic breast cancer in mouse models, but also preferentially accumulates in brain tumor tissues rather than normal brain tissues, showing potential for inhibiting intracranial tumor metastasis. As a humoral immune stimulant, DV1 TFA induces the production of specific IgG, neutralizing antibodies and cellular immune responses, thereby providing the host with protection against lethal challenges. DV1 TFA has been applied to studies on CXCR4-expressing cancers, glioblastoma, dengue fever and other related diseases .

HY-P11090

TpD	MHC	Inflammation/Immunology
TpD is a chimeric T-helper epitope. TpD has a special site that cathepsin can cut. Immunization with TpD produces a strong antibody response. TpD promotes long-term CD4 immune responses in animals and humans. TpD binds well to many human MHC class II types, mainly HLA-DRB1. It also binds some other HLA alleles like DRB3, DRB4, DRB5, DP, and DQ. TpD can be used to improve the immune response of peptide vaccines .

HY-P11299

EBNA-1 (386–405 aa)	EBV	Infection Neurological Disease Inflammation/Immunology
EBNA-1 (386-405 aa) is a cross-reactive viral antigen peptide. EBNA-1 (386-405 aa) has a high molecular similarity to GlialCAM (370-389 aa) and it induces the production of cross-reactive antibodies that recognize both EBV antigens and glial cells in the central nervous system, thereby triggering autoimmune responses. EBNA-1 (386-405 aa) can used for Epstein-Barr virus (EBV) infection and multiple sclerosis (MS) research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N1470

Plantagoside	Plantaginaceae Structural Classification Flavonoids Classification of Application Fields Flavonones Phenols Polyphenols Metabolic Disease Plantago asiatica L. Plants Disease Research Fields Source Classification	Glycosidase
Plantagoside is a flavanone glucoside found in Plantago asiatica seeds, acting as a specific non-competitive α-mannosidase inhibitor with IC₅₀ values of 5 μM and a K_i of 2.7 μM (jack bean). Plantagoside suppresses antibody response and Concanavalin A (HY-P2149)-induced lymphocyte proliferation in mouse spleen cells. Plantagoside inhibits the Maillard reaction, advanced glycation end product formation, and glycation-dependent protein-protein cross-link formation. Plantagoside can be used for the research of diabetes .

HY-129502

Fibrostatin C P-23924C	Natural Products Microorganisms Source Classification	HIF/HIF Prolyl-Hydroxylase
Fibrostatin C (P-23924C) is an orally active prolyl hydroxylase inhibitor that also inhibits collagen biosynthesis. Fibrostatin C also increases the number of cytoplasmic granules immunoreactive with antibodies to collagen I or III. Fibrostatin C inhibits the secretion of type I collagen in Tenon's capsule fibroblasts. Fibrostatin C is promising for research of the wound fibrotic response in the wound of glaucoma filtering surgery .

HY-N1470R

Plantagoside (Standard)	Plantaginaceae Structural Classification Flavonoids Flavonones Phenols Polyphenols Plantago asiatica L. Plants Source Classification	Reference Standards Glycosidase
Plantagoside (Standard) is the analytical standard of Plantagoside (HY-N1470). This product is intended for research and analytical applications. Plantagoside is a flavanone glucoside found in Plantago asiatica seeds, acting as a specific non-competitive α-mannosidase inhibitor with IC₅₀ values of 5 μM and a K_i of 2.7 μM (jack bean). Plantagoside suppresses antibody response and Concanavalin A (HY-P2149)-induced lymphocyte proliferation in mouse spleen cells. Plantagoside inhibits the Maillard reaction, advanced glycation end product formation, and glycation-dependent protein-protein cross-link formation. Plantagoside can be used for the research of diabetes .

Host:	Mouse (14) Rabbit (28)
Reactivity:	Human (37) Rat (27) Mouse (30) Pig (1)
Application:	IHC-P (27) ICC/IF (15) mIHC (1) IF-Tissue (6) IP (7) IHC-F (9) WB (36) ChIP (1) FC (3) ELISA (8)
Isotype:	IgG (32) IgG1 (6)
Conjugation:	Non-conjugated (42)
Clonality:	Polyclonal (2) Monoclonal (30) Recombinant (14)
Modification:	Phosphorylated (1) Unmodified (31)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P87085

	SRF Antibody (YA6778) c fos serum response element binding factor antibody; c fos serum response element binding transcription factor antibody; ELK3 antibody; ERP antibody; MCM 1 antibody; MCM1 antibody; OTTHUMP00000039820 antibody; SAP2 antibody; Serum response factor antibody; SRF antibody; c fos serum response element binding factor antibody; c fos serum response element binding transcription factor antibody; ELK3 antibody; ERP antibody; MCM 1 antibody; MCM1 antibody; OTTHUMP00000039820 antibody; SAP2 antibody; Serum response factor antibody; SRF antibody; SRF serum response factor c fos serum response element binding transcription factor antibody; SRF_HUMAN antibody;	WB, ICC/IF, IHC-P, FC, IP	Human, Mouse, Rat
	SRF Antibody (YA6778) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SRF.

HY-P82858

	PAR4 Antibody (YA2603) PAWR; PAR4; PRKC apoptosis WT1 regulator protein; Prostate apoptosis response 4 protein; Par-4	WB	Human, Mouse, Rat
	PAR4 Antibody (YA2603) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PAR4.

HY-P85314

	PAR4 Antibody (YA5006) PAWR; PAR4; PRKC apoptosis WT1 regulator protein; Prostate apoptosis response 4 protein; Par-4	WB, IHC-P, ELISA	Human
	PAR4 Antibody (YA5006) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to PAR4.

HY-P80760

	MyD88 Antibody MYD88; Myeloid differentiation primary response protein MyD88	ICC/IF, WB, IHC-F, IHC-P, ELISA	Human, Mouse, Rat
	MyD88 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to MyD88.

HY-P85714

	Myd88 Antibody (YA5406) Myeloid differentiation primary response protein MyD88	IHC-P	Human, Mouse, Rat
	Myd88 Antibody (YA5406) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Myd88.

HY-P85314A

	PAR4 Antibody (YA5006)(PBS only) PAWR; PAR4; PRKC apoptosis WT1 regulator protein; Prostate apoptosis response 4 protein; Par-4	WB, IHC-P, ELISA	Human
	PAR4 Antibody (YA5006) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to PAR4.

HY-P80902

	STAT3 Antibody (YA666) 1 Publications Verification STAT3; APRF; Signal transducer and activator of transcription 3; Acute-phase response factor	WB, IHC-P	Human, Rat, Mouse
	STAT3 Antibody (YA666) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to STAT3.

HY-P86382

	STAT3 Antibody (YA6074) STAT3; APRF; Signal transducer and activator of transcription 3; Acute-phase response factor	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	STAT3 Antibody (YA6074) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to STAT3.

HY-P80857

	Phospho-STAT3 (Tyr705) Antibody 1 Publications Verification STAT3; APRF; Signal transducer and activator of transcription 3; Acute-phase response factor	WB, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	Phospho-STAT3 (Tyr705) Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Phospho-STAT3 (Tyr705).

HY-P80902A

	STAT3 Antibody (YA666)(PBS only) STAT3; APRF; Signal transducer and activator of transcription 3; Acute-phase response factor	WB, IHC-P	Human, Mouse, Rat
	STAT3 Antibody (YA666)(PBS only) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to STAT3.

HY-P810353

	NOXA Antibody (YA9675) Adult T cell leukemia derived PMA responsive, APR, APR_HUMAN, ATL-derived, Immediate early response protein APR, Immediate-early-response protein APR, NOXA, Phorbol 12 myristate 13 acetate induced protein 1, Phorbol-12-myristate-13-acetate-induced protein 1, PMA induced protein 1	WB, IHC-P	Human, Mouse, Rat
	NOXA Antibody (YA9675) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to NOXA.

HY-P86847

	DPF2 Antibody (YA6540) Apoptosis response zinc finger protein antibody; BAF45D antibody; BRG1-associated factor 45D antibody; D4 antibody; D4 zinc and double PHD fingers family 2 antibody; Double PHD fingers 2 antibody; double PHD fingers family 2 antibody; DPF 2 antibody; DPF2 antibody; MGC10180 antibody; Apoptosis response zinc finger protein antibody; BAF45D antibody; BRG1-associated factor 45D antibody; D4 antibody; D4 zinc and double PHD fingers family 2 antibody; Double PHD fingers 2 antibody; double PHD fingers family 2 antibody; DPF 2 antibody; DPF2 antibody; MGC10180 antibody; Protein requiem antibody; REQ antibody; REQU_HUMAN antibody; Requiem antibody; Requiem apoptosis response zinc finger antibody; UBI D4 antibody; ubi-d4 antibody; UBID 4 antibody; UBID4 antibody; zinc and double PHD fingers family 2 antibody; Zinc finger protein ubi d4 antibody; Zinc finger protein ubi-d4 antibody;	WB, ICC/IF, IHC-P	Human, Mouse, Rat
	DPF2 Antibody (YA6540) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DPF2.

HY-P81410

	MEF2B Antibody (YA1155) MEF2B; XMEF2; Myocyte-specific enhancer factor 2B; RSRFR2; Serum response factor-like protein 2	IHC-P	Human
	MEF2B Antibody (YA1155) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MEF2B.

HY-P80552

	ATF2 Antibody (YA606) Activating transcription factor 2 antibody; Activating transcription factor 2 splice variant ATF2 var2 antibody; ATF 2 antibody; Atf-2 antibody; Atf2 antibody; ATF2 protein antibody; ATF2_HUMAN antibody; cAMP response Element Binding Protein 2 antibody; cAMP response element binding protein CRE BP1 antibody; cAMP response element-binding protein CRE-BP1 antibody; cAMP responsive element binding protein 2, formerly antibody; cAMP-dependent transcription factor ATF-2 antibody; cAMP-responsive element-binding protein 2 antibody; CRE BP1 antibody; CRE-BP antibody; CREB 2 antibody; CREB-2 antibody; CREB2 antibody; CREBP1 antibody; Cyclic AMP dependent transcription factor ATF 2 antibody; Cyclic AMP-dependent transcription factor ATF-2 antibody; Cyclic AMP-responsive element-binding protein 2 antibody; D130078H02Rik antibody; D18875 antibody; HB 16 antibody; HB16 antibody; Histone acetyltransferase ATF2 antibody; MGC105211 antibody; MGC105222 antibody; MGC111558 antibody; MGC142504 antibody; mXBP antibody; MXBP protein antibody; Tg(Gzma-Klra1)7Wum antibody; TREB 7 antibody; TREB7 antibody	WB	Human, Mouse, Rat
	ATF2 Antibody (YA606) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ATF2.

HY-P81410A

	MEF2B Antibody (YA1155)(PBS only) MEF2B; XMEF2; Myocyte-specific enhancer factor 2B; RSRFR2; Serum response factor-like protein 2	IHC-P	Human
	MEF2B Antibody (YA1155) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MEF2B.

HY-P80552A

	ATF2 Antibody (YA606)(PBS only) Activating transcription factor 2 antibody; Activating transcription factor 2 splice variant ATF2 var2 antibody; ATF 2 antibody; Atf-2 antibody; Atf2 antibody; ATF2 protein antibody; ATF2_HUMAN antibody; cAMP response Element Binding Protein 2 antibody; cAMP response element binding protein CRE BP1 antibody; cAMP response element-binding protein CRE-BP1 antibody; cAMP responsive element binding protein 2, formerly antibody; cAMP-dependent transcription factor ATF-2 antibody; cAMP-responsive element-binding protein 2 antibody; CRE BP1 antibody; CRE-BP antibody; CREB 2 antibody; CREB-2 antibody; CREB2 antibody; CREBP1 antibody; Cyclic AMP dependent transcription factor ATF 2 antibody; Cyclic AMP-dependent transcription factor ATF-2 antibody; Cyclic AMP-responsive element-binding protein 2 antibody; D130078H02Rik antibody; D18875 antibody; HB 16 antibody; HB16 antibody; Histone acetyltransferase ATF2 antibody; MGC105211 antibody; MGC105222 antibody; MGC111558 antibody; MGC142504 antibody; mXBP antibody; MXBP protein antibody; Tg(Gzma-Klra1)7Wum antibody; TREB 7 antibody; TREB7 antibody	WB	Human, Mouse, Rat
	ATF2 Antibody (YA606) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ATF2.

HY-P86967

	MTF1 Antibody (YA6660) Metal regulatory transcription factor 1 antibody; Metal response element binding transcription factor 1 antibody; Metal responsive transcription factor 1 antibody; MRE binding transcription factor antibody; MRE-binding transcription factor 1 antibody; MRE-binding transcription factor antibody; MTF 1 antibody; MTF1 antibody; MTF1_HUMAN antibody; Transcription factor MTF-1 antibody; Metal regulatory transcription factor 1 antibody; Metal response element binding transcription factor 1 antibody; Metal responsive transcription factor 1 antibody; MRE binding transcription factor antibody; MRE-binding transcription factor 1 antibody; MRE-binding transcription factor antibody; MTF 1 antibody; MTF1 antibody; MTF1_HUMAN antibody; Transcription factor MTF-1 antibody; Transcription factor MTF1 antibody; Zinc regulatory factor antibody; ZRF antibody;	WB, ICC/IF, IHC-P, FC	Human
	MTF1 Antibody (YA6660) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MTF1.

HY-P82931

	CD266 Antibody (YA2676) CD266 antigen; FGF inducible 14; Fibroblast growth factor inducible immediate early response protein 14; FN14; TNFRSF 12A; Tweak receptor; TweakR	WB, IHC-P, IP	Human, Mouse, Rat
	CD266 Antibody (YA2676) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD266.

HY-P86731

	CREB-1 Antibody (YA6423) Active transcription factor CREB; cAMP response element binding protein; cAMP responsive element binding protein 1; CREB 1; CREB1; MGC9284; Transactivator protein; CREB.	WB, IHC-P, IHC-F, IF-Tissue	Human, Mouse
	CREB-1 Antibody (YA6423) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to CREB-1.

HY-P82931A

	CD266 Antibody (YA2676)(PBS only) CD266 antigen; FGF inducible 14; Fibroblast growth factor inducible immediate early response protein 14; FN14; TNFRSF 12A; Tweak receptor; TweakR	WB, IHC-P, IP	Human, Mouse, Rat
	CD266 Antibody (YA2676) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD266.

HY-P81306

	SAFB1 Antibody (YA1042) SAFB; HAP; HET; SAFB1; Scaffold attachment factor B1; SAF-B; SAF-B1; HSP27 estrogen response element-TATA box-binding protein; HSP27 ERE-TATA-binding protein	WB, ICC/IF, ChIP	Human
	SAFB1 Antibody (YA1042) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SAFB1.

HY-P81306A

	SAFB1 Antibody (YA1043) SAFB; HAP; HET; SAFB1; Scaffold attachment factor B1; SAF-B; SAF-B1; HSP27 estrogen response element-TATA box-binding protein; HSP27 ERE-TATA-binding protein	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse
	SAFB1 Antibody (YA1043) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SAFB1.

HY-P86731A

	CREB-1 Antibody (YA6423)(PBS only) Active transcription factor CREB; cAMP response element binding protein; cAMP responsive element binding protein 1; CREB 1; CREB1; MGC9284; Transactivator protein; CREB.	WB, IHC-P, IHC-F, IF-Tissue	Human, Mouse
	CREB-1 Antibody (YA6423) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to CREB-1.

HY-P85394

	TORC3 Antibody (YA5086) CRTC3; TORC3; CREB-regulated transcription coactivator 3; Transducer of regulated cAMP response element-binding protein 3; TORC-3; Transducer of CREB protein 3	WB, IHC-P, IHC-F, ICC/IF, IF-Tissue	Human, Mouse, Rat
	TORC3 Antibody (YA5086) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to TORC3.

HY-P82818

	CRMP3 Antibody (YA2563) DPYSL4; CRMP3; ULIP4; Dihydropyrimidinase-related protein 4; DRP-4; Collapsin response mediator protein 3; CRMP-3; UNC33-like phosphoprotein 4; ULIP-4	WB	Rat
	CRMP3 Antibody (YA2563) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CRMP3.

HY-P81306AA

	SAFB1 Antibody (YA1043)(PBS only) SAFB; HAP; HET; SAFB1; Scaffold attachment factor B1; SAF-B; SAF-B1; HSP27 estrogen response element-TATA box-binding protein; HSP27 ERE-TATA-binding protein	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse
	SAFB1 Antibody (YA1043) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SAFB1.

HY-P82818A

	CRMP3 Antibody (YA2563)(PBS only) DPYSL4; CRMP3; ULIP4; Dihydropyrimidinase-related protein 4; DRP-4; Collapsin response mediator protein 3; CRMP-3; UNC33-like phosphoprotein 4; ULIP-4	WB	Rat
	CRMP3 Antibody (YA2563) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CRMP3.

HY-P82181

	EGR2 Antibody (YA1926) EGR2; KROX20; E3 SUMO-protein ligase EGR2; AT591; E3 SUMO-protein transferase ERG2 Curated; Early growth response protein 2 (EGR-2); Zinc finger protein Krox-20;	WB	Human, Mouse, Rat
	EGR2 Antibody (YA1926) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to EGR2.

HY-P86176

	EGR1 Antibody (YA5868) EGR1; KROX24; ZNF225; Early growth response protein 1; EGR-1; AT225; Nerve growth factor-induced protein A; NGFI-A; Transcription factor ETR103; Transcription factor Zif268; Zinc finger protein 225; Zinc finger protein Krox-24	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	EGR1 Antibody (YA5868) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to EGR1.

HY-P85131

	EGR1 Antibody (YA4823) EGR1; KROX24; ZNF225; Early growth response protein 1; EGR-1; AT225; Nerve growth factor-induced protein A; NGFI-A; Transcription factor ETR103; Transcription factor Zif268; Zinc finger protein 225; Zinc finger protein Krox-24	WB, ELISA	Human
	EGR1 Antibody (YA4823) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to EGR1.

HY-P85478

	TORC1 Antibody (YA5170) CRTC1; KIAA0616; MECT1; TORC1; WAMTP1; CREB-regulated transcription coactivator 1; Mucoepidermoid carcinoma translocated protein 1; Transducer of regulated cAMP response element-binding protein 1; TORC-1; Transducer of CREB protein 1	WB, FC, ICC/IF	Human, Mouse, Rat, Pig
	TORC1 Antibody (YA5170) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to TORC1.

HY-P86921

	Iba1 Antibody(YA6614) AIF 1 antibody; AIF-1 antibody; Aif1 antibody; AIF1 protein antibody; AIF1_HUMAN antibody; Allograft inflammatory factor 1 antibody; Allograft inflammatory factor 1 splice variant G antibody; allograft inflammatory factor-1 splice variant Hara-1 antibody; balloon angioplasty responsive transcription antibody; BART 1 antibody; AIF 1 antibody; AIF-1 antibody; Aif1 antibody; AIF1 protein antibody; AIF1_HUMAN antibody; Allograft inflammatory factor 1 antibody; Allograft inflammatory factor 1 splice variant G antibody; allograft inflammatory factor-1 splice variant Hara-1 antibody; balloon angioplasty responsive transcription antibody; BART 1 antibody; G1 antibody; G1 putative splice variant of allograft inflamatory factor 1 antibody; IBA 1 antibody; IBA1 antibody; interferon gamma responsive transcript antibody; Interferon responsive transcript 1 antibody; interferon responsive transcript factor 1 antibody; Ionized calcium binding adapter molecule 1 antibody; Ionized calcium-binding adapter molecule 1 antibody; ionized calcium-binding adapter molecule antibody; IRT 1 antibody; IRT1 antibody; Microglia response factor antibody; MRF1 antibody; Protein g1 antibody;	mIHC	Mouse
	Iba1 Antibody(YA6614) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Iba1.

HY-P81717

	NUR77 Antibody (YA1462) NR4A1; GFRP1; HMR; NAK1; Nuclear receptor subfamily 4 group A member 1; Early response protein NAK1; Nuclear hormone receptor NUR/77; Nur77; Orphan nuclear receptor HMR; Orphan nuclear receptor TR3; ST-59; Testicular receptor 3	WB	Human, Mouse, Rat
	NUR77 Antibody (YA1462) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NUR77.

HY-P85538

	SAFB1 Antibody (YA5230) DKFZp779C1727; glutathione S transferase fusion protein; HAP; HET; HSP27 ERE TATA binding protein; HSP27 ERE-TATA-binding protein; HSP27 estrogen response element-TATA box-binding protein; SAF B; SAF-B1; SAFB 1; SAFB; SAFB1; SAFB1_HUMAN; scaffold attachment factor B1.	WB, ICC/IF	Human
	SAFB1 Antibody (YA5230) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to SAFB1.

HY-P81717A

	NUR77 Antibody (YA1462)(PBS only) NR4A1; GFRP1; HMR; NAK1; Nuclear receptor subfamily 4 group A member 1; Early response protein NAK1; Nuclear hormone receptor NUR/77; Nur77; Orphan nuclear receptor HMR; Orphan nuclear receptor TR3; ST-59; Testicular receptor 3	WB	Human, Mouse, Rat
	NUR77 Antibody (YA1462) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NUR77.

HY-P86737

	phospho-STAT3 (Tyr705) Antibody (YA6429) STAT3(phospho Y705); p-STAT3(phospho Y705); phospho-Stat3(pTyr705); STAT3(phospho-Tyr705); p-STAT3(Tyr705); phosphorylated Stat3(pTyr705); p-Stat3; Acute Phase response Factor; APRF; DNA binding protein APRF; FLJ20882; MGC16063; Signal Transductor and Activator of Transcription 3; STAT 3; STAT3_HUMAN.	IHC-P, IHC-F, IF-Tissue	Human, Rat
	phospho-STAT3 (Tyr705) Antibody (YA6429) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to phospho-STAT3 (Tyr705).

HY-P86737A

	phospho-STAT3 (Tyr705) Antibody (YA6429)(PBS only) STAT3(phospho Y705); p-STAT3(phospho Y705); phospho-Stat3(pTyr705); STAT3(phospho-Tyr705); p-STAT3(Tyr705); phosphorylated Stat3(pTyr705); p-Stat3; Acute Phase response Factor; APRF; DNA binding protein APRF; FLJ20882; MGC16063; Signal Transductor and Activator of Transcription 3; STAT 3; STAT3_HUMAN.	IHC-P, IHC-F, IF-Tissue	Human, Rat
	phospho-STAT3 (Tyr705) Antibody (YA6429) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to phospho-STAT3 (Tyr705).

HY-P86692

	AIF1 Antibody (YA6384) AIF 1; AIF1 protein; IBa1; iba-1; IBa 1; allograft inflammatory factor 1; Allograft inflammatory factor 1 splice variant G; balloon angioplasty responsive transcription; BART 1; G1; G1 putative splice variant of allograft inflamatory factor 1; IBA 1; IBA1; interferon gamma responsive transcript; Ionized calcium binding adapter molecule 1; ionized calcium-binding adapter molecule; IRT 1; IRT1; Microglia response factor; MRF1; Protein G1.	WB	Mouse
	AIF1 Antibody (YA6384) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to AIF1.

HY-P86699

	Aquaporin 1 Antibody (YA6391) AQP 1; AQP-1; AQP1_HUMAN; Aquaporin-1; Aquaporin-CHIP; Channel like integral membrane protein 28 kDa; MGC26324; Water channel protein CHIP 29; AQP CHIP; AQP1; Aquaporin CHIP; Aquaporin1; Aquaporin 1; Channel forming integral protein 28kDa; CHIP 28; CHIP28; CO; Colton blood group; Growth factor induced delayed early response protein; Urine water channel; Water channel protein CHIP29; Water channel protein for red blood cells and kidney proximal tubule.	WB, IF-Tissue, IHC-P, IHC-F	Human, Mouse, Rat
	Aquaporin 1 Antibody (YA6391) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Aquaporin 1.

HY-P86692A

	AIF1 Antibody (YA6384)(PBS only) AIF 1; AIF1 protein; IBa1; iba-1; IBa 1; allograft inflammatory factor 1; Allograft inflammatory factor 1 splice variant G; balloon angioplasty responsive transcription; BART 1; G1; G1 putative splice variant of allograft inflamatory factor 1; IBA 1; IBA1; interferon gamma responsive transcript; Ionized calcium binding adapter molecule 1; ionized calcium-binding adapter molecule; IRT 1; IRT1; Microglia response factor; MRF1; Protein G1.	WB	Mouse
	AIF1 Antibody (YA6384) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to AIF1.

HY-P85890

	Iba1 Antibody (YA5582) AIF 1; AIF-1; Aif1; AIF1 protein; AIF1_HUMAN; Allograft inflammatory factor 1; Allograft inflammatory factor 1 splice variant G; allograft inflammatory factor-1 splice variant Hara-1; balloon angioplasty responsive transcription; BART 1; G1; G1 putative splice variant of allograft inflamatory factor 1; IBA 1; IBA1; interferon gamma responsive transcript; Interferon responsive transcript 1; interferon responsive transcript factor 1; Ionized calcium binding adapter molecule 1; Ionized calcium-binding adapter molecule 1; ionized calcium-binding adapter molecule; IRT 1; IRT1; Microglia response factor; MRF1; Protein g1;	IHC-P, WB, ICC/IF, ELISA	Human, Mouse, Rat
	Iba1 Antibody (YA5582) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Iba1.

HY-P86536

	Iba1 Antibody (YA6228) AIF 1; AIF-1; Aif1; AIF1 protein; AIF1_HUMAN; Allograft inflammatory factor 1; Allograft inflammatory factor 1 splice variant G; allograft inflammatory factor-1 splice variant Hara-1; balloon angioplasty responsive transcription; BART 1; G1; G1 putative splice variant of allograft inflamatory factor 1; IBA 1; IBA1; interferon gamma responsive transcript; Interferon responsive transcript 1; interferon responsive transcript factor 1; Ionized calcium binding adapter molecule 1; Ionized calcium-binding adapter molecule 1; ionized calcium-binding adapter molecule; IRT 1; IRT1; Microglia response factor; MRF1; Protein g1;	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Iba1 Antibody (YA6228) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Iba1.

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Cat. No.	Product Name		Classification

HY-159102

PVP-037.2		Azide
PVP-037.2 is a TLR7/8 agonist. PVP-037.2 can serve as an adjuvant to enhance vaccine-induced T_H1 type immune responses, increasing the production of antigen-specific antibodies IgG1 and IgG2c .

HY-163045

4-Azidophenylarsonic acid		Azide
4-Azidophenylarsonic acid, a Hapten that contains a diazonium group, is a probes of antibody response and immunorecognition .

Cat. No.	Product Name		Classification

HY-146244

Agatolimod 1 Publications Verification ODN 2006; PF-3512676; CpG 7909; ODN 7909		CpG ODNs
Agatolimod ((ODN 2006; PF-3512676; CpG 7909)) is a TLR9 agonist and immunomodulator with an EC₅₀ of 180 nM against human TLR9. Agatolimod activates and upregulates the expression of both TLR9 and TLR6, and mediates downstream signaling pathways via IRAK4, IRF5, IRF7. Agatolimod induces Th1-type innate and adaptive immune responses, activates various immune cells and promotes antigen presentation, regulates antibody levels and immune cell infiltration, upregulates the secretion of multiple cytokines, induces apoptosis and cell cycle arrest, enhances cytotoxicity, and clears intracellular Salmonella. Agatolimod is applicable to research on COVID-19, breast cancer, lung adenocarcinoma, HPV-related tumors, melanoma, and salmonellosis .

HY-153808A

Incomplete Freund's adjuvant (IFA) 4 Publications Verification		Adjuvant
Incomplete Freund's adjuvant (IFA) (Montanide ISA-51) is an immunoadjuvant emulsified with antigen by its discoverer Jules T. Freund. Incomplete Freund's adjuvant (IFA) does not contain inactivated tuberculosis bacilli and consists of petroleum jelly containing lanolin. Incomplete Freund's adjuvant (IFA) induces high antibody titers and long-lasting effector T cell responses with no long-term effects on collagen disease, tumors, or death. Complete Freund's adjuvant (CFA) (HY-153808) is another type of Freund's Adjuvant that stimulates a stronger immune response .

HY-150726

ODN 1668 1 Publications Verification		CpG ODNs
ODN 1668, a class B CpG ODN (oligodeoxynucleotide), is a TLR-9 agonist. ODN 1668 has strong immune regulatory properties, can enhance the level of antibody IgG2 subtype, promote the immune response of T cells and B cells, and can be used in the study of vaccine adjuvants. In addition, CpG ODN 1668 induces an antimicrobial immune response via a CaTLR9 dependent pathway in groupers. Sequence: 5'-tccatgacgttcctgatgct-3’ .

HY-150726C

ODN 1668 sodium 1 Publications Verification		CpG ODNs
ODN 1668 sodium, a class B CpG ODN (oligodeoxynucleotide), is a TLR-9 agonist. ODN 1668 sodium has strong immune regulatory properties, can enhance the level of antibody IgG2 subtype, promote the immune response of T cells and B cells, and can be used in the study of vaccine adjuvants. In addition, CpG ODN 1668 sodium induces an antimicrobial immune response via a CaTLR9 dependent pathway in groupers. Sequence: 5'-tccatgacgttcctgatgct-3’ .

HY-159746

Carbomer adjuvant (HS801)		Adjuvant
Carbomer adjuvant (HS801) is an adjuvant composed of carbomer and cationic polymers. This adjuvant is safe, non-toxic, and metabolizable. It can enhance the immune response, increase the antibody titer of each antigen component of the vaccine after immunization, and reduce the number of immunizations required. It is suitable for various veterinary vaccines. It is recommended for use in porcine circovirus, mycoplasma hyopneumoniae, and haemophilus parasuis.

HY-153209

Adjuvant-4		Adjuvant
Adjuvant-4 is a vaccine adjuvant that enhances antigen-specific antibody titers and cytotoxic T lymphocyte (CTL) responses . Adjuvant is generally an oil-in-water emulsifier of mineral oil and mannitol monooleate.

HY-159749

M902		Adjuvant
M902 is a new type of mineral oil-based adjuvant, which belongs to oil-in-water (O/W) emulsion. It rapidly stimulates the body to produce an immune response, has a low oil content, high safety, can induce natural immune responses, improve the efficiency of antigen uptake and presentation, induce the production of various cytokines, and increase the level of specific antibodies against antigens in the animal body. It is applicable to various veterinary vaccines, including inactivated vaccines and genetically engineered subunit vaccines, such as vaccine for Porcine Circovirus and Mycoplasma Hyopneumoniae.

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