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Efzofitimod

(Synonyms: ATYR-1923; KRP-R120)
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Efzofitimod is a splice variant of the aminoacyl-tRNA synthetase HARS1, which is fused with the Fc segment of a human antibody. Efzofitimod targets the neuronal phospholipid NRP2 (neuropilin-2) and has anti-inflammatory and immunomodulatory activities. Efzofitimod can downregulate the innate and adaptive immune responses in inflammatory disease states, suppressing indirect lung disease (ILD).

For research use only. We do not sell to patients.

  • Purity: 99.29%
  • CAS No.: 2566615-11-8
  • Molecular Weight:64.54 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Efzofitimod
  • Experimental Validation Results for Efzofitimod
  • Efzofitimod Chemical Structure
    Efzofitimod Chemical Structure
CAS No.: 2566615-11-8
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Efzofitimod Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Homo sapiens HARS1 (histidyl-tRNA synthetase 1)

  • 1/16

    Immobilized Efzofitimod can bind Anti-HARS antibody. The EC50 for this effect is 36.03 ng/mL.

  • Efzofitimod Chemical Structure
    1/16
  • Efzofitimod
  • Immobilized Efzofitimod can bind Anti-HARS antibody. The EC50 for this effect is 36.03 ng/mL.
  • Homo sapiens HARS1 (histidyl-tRNA synthetase 1)