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Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate (Synonyms: MOG (35-55) (acetate))

Cat. No.: HY-P1240B
Handling Instructions

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate is a minor component of CNS myelin. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat produces a relapsing-remitting neurological disease with extensive plaque-like demyelination. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate induces strong T and B cell responses and is highly encephalitogenic.

For research use only. We do not sell to patients.

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Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate Chemical Structure

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate Chemical Structure

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Description

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate is a minor component of CNS myelin. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat produces a relapsing-remitting neurological disease with extensive plaque-like demyelination. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate induces strong T and B cell responses and is highly encephalitogenic[1][2][3].

In Vivo

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG) is a highly autoantigenic molecule capable of inducing severe demyelinating disease[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Inbred female NOD/Lt (H-P'), C57BL/6 (H-2b), C57BL/10 (H-2'), DBAj2 (H-2d), BALB/c (H-2"), BALB/c (H-2b), C3H/HeJ (H-2k), BI0.Br (H-2k), BI0.S (H-2'), SJL/J (H-2') and PL/J (H-2") mice[2].
Dosage: 50 μg (100 μg total).
Administration: Injected in each hind footpad.
Result: Mice receiving 50 μg and 100 μg of peptide has more dramatic weight losses during the course of the disease than mice injected with 150 μg.
Molecular Weight

2642.00

Formula

C₁₂₀H₁₈₁N₃₅O₃₁S

Sequence Shortening

MEVGWYRSPFSRVVHLYRNGK

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate
Cat. No.:
HY-P1240B
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