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  4. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate  (Synonyms: MOG (35-55) (acetate))

Cat. No.: HY-P1240B Purity: 99.82%
COA Handling Instructions

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) acetate is a minor component of CNS myelin. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate has encephalitogenic activity and induces T cell proliferative. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate induces Th1 cytokine response as well as relatively high levels of IgG antibodies. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate produces a relapsing-remitting neurological disease with extensive plaque-like demyelination.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate Chemical Structure

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate Chemical Structure

Size Price Stock Quantity
1 mg USD 70 In-stock
5 mg USD 190 In-stock
10 mg USD 305 In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 4 publication(s) in Google Scholar

Other Forms of Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate:

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  • Biological Activity

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Description

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) acetate is a minor component of CNS myelin. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate has encephalitogenic activity and induces T cell proliferative. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate induces Th1 cytokine response as well as relatively high levels of IgG antibodies. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate produces a relapsing-remitting neurological disease with extensive plaque-like demyelination[1][2][3].

In Vitro

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55); 0-50 μg/mL; 72 h; lymph nodes cells) acetate induces T cell proliferative and secretes Th1 cytokines including IFN-γ, TNF-α, IL-10, IL-4 and IL-5. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate increases the level of IgG[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (acetate) can be used in animal modeling to construct mouse encephalomyelitis model.

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55); 200 μg (0.2 mL); i.p.; once, for 38 d) acetate has encephalitogenic activity in HLA-DR2 (DRB1*1501) mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: HLA-DR2 (DRB1*1501) mice[1]
Dosage: 200 μg (0.2 mL)
Administration: Intraperitoneal injection; once, for 38 days
Result: Resulted in paralysis of both hind and forelimbs.
Molecular Weight

2642.00

Formula

C120H181N35O31S

Appearance

Solid

Color

White to off-white

Sequence Shortening

MEVGWYRSPFSRVVHLYRNGK

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (37.85 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.3785 mL 1.8925 mL 3.7850 mL
5 mM 0.0757 mL 0.3785 mL 0.7570 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.3785 mL 1.8925 mL 3.7850 mL 9.4625 mL
5 mM 0.0757 mL 0.3785 mL 0.7570 mL 1.8925 mL
10 mM 0.0379 mL 0.1893 mL 0.3785 mL 0.9463 mL
15 mM 0.0252 mL 0.1262 mL 0.2523 mL 0.6308 mL
20 mM 0.0189 mL 0.0946 mL 0.1893 mL 0.4731 mL
25 mM 0.0151 mL 0.0757 mL 0.1514 mL 0.3785 mL
30 mM 0.0126 mL 0.0631 mL 0.1262 mL 0.3154 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate
Cat. No.:
HY-P1240B
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