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Anti-Mouse/Human CD44 Antibody (IM7)

3 Cited Publications
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Based on 3 publication(s) in Google Scholar

Anti-Mouse/Human CD44 Antibody (IM7) is an anti-huamn and mouse CD44 IgG2b monoclonal antibody that recognizes a conserved epitope outside the HA-binding domain of the CD44 molecule. Anti-Mouse/Human CD44 Antibody (IM7) exerts a potent anti-inflammatory effect by inducing the shedding of cell surface CD44, significantly improving symptoms in mice with rheumatoid arthritis without affecting relevant immune responses. Anti-Mouse/Human CD44 Antibody (IM7) can be used for researches on inflammation conditions and cancer such as arthritis and osteosarcoma.

For research use only. We do not sell to patients.

  • Purity : 99.07%
  • Molecular Weight:150 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Anti-Mouse/Human CD44 Antibody (IM7)
  • Experimental Validation Results for Anti-Mouse/Human CD44 Antibody (IM7)
  • Experimental Validation Results for Anti-Mouse/Human CD44 Antibody (IM7)
  • Experimental Validation Results for Anti-Mouse/Human CD44 Antibody (IM7)
  • Experimental Validation Results for Anti-Mouse/Human CD44 Antibody (IM7)
  • Experimental Validation Results for Anti-Mouse/Human CD44 Antibody (IM7)
  • Anti-Mouse/Human CD44 Antibody (IM7) Chemical Structure
    Anti-Mouse/Human CD44 Antibody (IM7) Chemical Structure
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Anti-Mouse/Human CD44 Antibody (IM7) Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Publications Citing Use of MedChemExpress (MCE) Anti-Mouse/Human CD44 Antibody (IM7)

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In Vivo Efficacy StudyHistological Imaging/StainingWBRT-PCRFlow Cytometry
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  • 1/16

    Immobilized CD44 Protein, Mouse (HEK293, His, HY-P74291) can bind Anti-Mouse CD44 Antibody (IM7). The EC50 for this effect is 0.165 μg/mL.

  • 1/16

    Anti-Mouse/Human CD44 Antibody (IM7) purchased from MedChemExpress. Usage Cited in: Cell Signal. 2025 Dec 11:112315. [Abstract]

    Customer Validation
     Anti-Mouse/Human CD44 Antibody (IM7) (100 μL; i.p.; 7 d) significantly attenuated body weight loss, reduced disease activity index (DAI) scores, and partially restored colon length in UC (ulcerative colitis) mice.

  • 1/16

    Anti-Mouse/Human CD44 Antibody (IM7) purchased from MedChemExpress. Usage Cited in: Cell Signal. 2025 Dec 11:112315. [Abstract]

    Customer Validation
     Anti-Mouse/Human CD44 Antibody (IM7) (100 μL; i.p.; 7 d) repaired mucosal epithelial barriers, diminished inflammatory infiltration, and improved histopathology scores in colon tissues of UC (ulcerative colitis) mice.

  • 1/16

    Anti-Mouse/Human CD44 Antibody (IM7) purchased from MedChemExpress. Usage Cited in: Cell Signal. 2025 Dec 11:112315. [Abstract]

    Customer Validation
     Anti-Mouse/Human CD44 Antibody (IM7) (10 μg/mL) reduced CD44 protein levels and elevated ATP7A expression in BMDM-derived Ly6Chi macrophages.

  • 1/16

    Anti-Mouse/Human CD44 Antibody (IM7) purchased from MedChemExpress. Usage Cited in: Cell Signal. 2025 Dec 11:112315. [Abstract]

    Customer Validation
     Anti-Mouse/Human CD44 Antibody (IM7) (10 μg/mL) reduced mRNA levels of pro-inflammatory cytokines IL-6 and TNF-α in BMDM-derived Ly6Chi macrophages.

  • 1/16

    Anti-Mouse/Human CD44 Antibody (IM7) purchased from MedChemExpress. Usage Cited in: Cell Signal. 2025 Dec 11:112315. [Abstract]

    Customer Validation
     Anti-Mouse/Human CD44 Antibody (IM7) (10 μg/mL) diminished the ROS proportion in BMDM-derived Ly6Chi macrophages.

  • Anti-Mouse/Human CD44 Antibody (IM7) Chemical Structure
    1/16
  • Anti-Mouse/Human CD44 Antibody (IM7)
  • Immobilized CD44 Protein, Mouse (HEK293, His, HY-P74291) can bind Anti-Mouse CD44 Antibody (IM7). The EC50 for this effect is 0.165 μg/mL.