2. Immunology/Inflammation
  3. C-type Lectin-like Receptors (CTLRs)
  4. Tesnatilimab

Tesnatilimab  (Synonyms: JNJ-64304500; IPH-2301; NN-8555)

Cat. No.: HY-P99389 Purity: 99.80%
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Tesnatilimab (JNJ-64304500) is a human IgG4 monoclonal antibody targeting NKG2D. Tesnatilimab can be studied in research for diseases such as Crohn’s disease (CD) and Inflammatory Bowel Disease (IBD). Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).

For research use only. We do not sell to patients.

CAS No. : 2242758-08-1

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Based on 1 publication(s) in Google Scholar

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Description

Tesnatilimab (JNJ-64304500) is a human IgG4 monoclonal antibody targeting NKG2D. Tesnatilimab can be studied in research for diseases such as Crohn’s disease (CD) and Inflammatory Bowel Disease (IBD). Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003)[1].

Molecular Weight

143.9 kDa

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Tesnatilimab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG4 kappa
Biological Activity
  • Immobilized NKG2D/CD314 Protein, Human can bind Tesnatilimab. The EC50 for this effect is 16.41 ng/mL.
Purity & Documentation

Purity: 99.80%

SDS (251 KB)

COA (291 KB)

Inhibitory Antibodies User Guide (602 KB)
References
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Tesnatilimab Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tesnatilimab2242758-08-1JNJ-64304500 IPH-2301 NN-8555JNJ64304500JNJ 64304500IPH2301IPH 2301IPH-2301NN8555NN 8555NN-8555C-type Lectin-like Receptors (CTLRs)IgG4NKG2Dmonoclonal antibodyanti-inflammatoryIBDCDInhibitorinhibitorinhibit

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