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Prezalumab

(Synonyms: AMG 557)
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Based on 1 Customer Validation

Prezalumab (AMG 557) is a humanized IgG2 monoclonal antibody targeting ICOSL. Prezalumab inhibits T cell activation and related immune responses by binding to ICOSL and blocking the interaction between ICOS and ICOSL. Prezalumab can be used in the research of autoimmune diseases and inflammatory diseases such as systemic lupus erythematosus. Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002).

For research use only. We do not sell to patients.

  • Purity: 99.41%
  • CAS No.: 1523164-68-2
  • Molecular Weight:145.5 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Prezalumab
  • Experimental Validation Results for Prezalumab
  • Experimental Validation Results for Prezalumab
  • Prezalumab Chemical Structure
  • Experimental Validation Results for Prezalumab
  • Experimental Validation Results for Prezalumab
  • Experimental Validation Results for Prezalumab
  • Prezalumab Chemical Structure
    Prezalumab Chemical Structure
CAS No.: 1523164-68-2
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG2 kappa

  • 1/16

    Immobilized B7-H2/ICOSLG Protein, Human can bind Prezalumab. The EC50 for this effect is 7.11 ng/mL.

  • 1/16

    Flow Cytometry analysis of Raji cells labelling B7-H2 (red) with Prezalumab (anti-B7-H2) (HY-P99414). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG2 kappa (HY-P99002). Black-Unlabelled control, cells without incubation with primary antibody.

  • Prezalumab Chemical Structure
    1/16
  • Prezalumab
  • Immobilized B7-H2/ICOSLG Protein, Human can bind Prezalumab. The EC50 for this effect is 7.11 ng/mL.
  • Flow Cytometry analysis of Raji cells labelling B7-H2 (red) with Prezalumab (anti-B7-H2) (HY-P99414). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG2 kappa (HY-P99002). Black-Unlabelled control, cells without incubation with primary antibody.