Copy Link Print Information

Prezalumab

(Synonyms: AMG 557)
1 Cited Publications
Customer Review

Based on 1 publication(s) in Google Scholar

Prezalumab (AMG 557) is a humanized IgG2 monoclonal antibody targeting ICOSL. Prezalumab inhibits T cell activation and related immune responses by binding to ICOSL and blocking the interaction between ICOS and ICOSL. Prezalumab can be used in the research of autoimmune diseases and inflammatory diseases such as systemic lupus erythematosus. Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002).

For research use only. We do not sell to patients.

  • Purity: 99.41%
  • CAS No.: 1523164-68-2
  • Molecular Weight:145.5 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Prezalumab
  • Experimental Validation Results for Prezalumab
  • Experimental Validation Results for Prezalumab
  • Prezalumab Chemical Structure
    Prezalumab Chemical Structure
CAS No.: 1523164-68-2
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Prezalumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • Purity & Documentation
  • References
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) Prezalumab

More

All Interleukin Related Isoforms

More
Keywords
MOQ
Minimum order quantity
100 mg

Get Quote In-stock

Other size
Get Quote
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Register
Sign in to MedChemExpress
Register New Account

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    Human IgG2 kappa

  • 1/16

    Immobilized B7-H2/ICOSLG Protein, Human can bind Prezalumab. The EC50 for this effect is 7.11 ng/mL.

  • 1/16

    Flow Cytometry analysis of Raji cells labelling B7-H2 (red) with Prezalumab (anti-B7-H2) (HY-P99414). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG2 kappa (HY-P99002). Black-Unlabelled control, cells without incubation with primary antibody.

  • Prezalumab Chemical Structure
    1/16
  • Prezalumab
  • Immobilized B7-H2/ICOSLG Protein, Human can bind Prezalumab. The EC50 for this effect is 7.11 ng/mL.
  • Flow Cytometry analysis of Raji cells labelling B7-H2 (red) with Prezalumab (anti-B7-H2) (HY-P99414). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG2 kappa (HY-P99002). Black-Unlabelled control, cells without incubation with primary antibody.