Phospho-STAT3 (Tyr705) Antibody

Cat. No.: HY-P80857: FAQs
Data Sheet SDS COA User Guide for Antibodies

Phospho-STAT3 (Tyr705) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 88 kDa, targeting to Phospho-STAT3 (Tyr705). It can be used for WB,IHC-P,ICC/IF,IP assays with tag free, in the background of Human, Mouse, Rat.

For research use only. We do not sell to patients.

Size	Price	Stock	Quantity
Free Sample		Apply now
10 μL	$70	In-stock	Estimated Time of Arrival: December 31
50 μL	$185	In-stock	Estimated Time of Arrival: December 31
100 μL	$300	In-stock	Estimated Time of Arrival: December 31
250 μL		Get quote

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Biological Activity
Technical Parameters
Properties
Documentation

Description	Phospho-STAT3 (Tyr705) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 88 kDa, targeting to Phospho-STAT3 (Tyr705). It can be used for WB,IHC-P,ICC/IF,IP assays with tag free, in the background of Human, Mouse, Rat.
Background	STAT3: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. This gene also plays a role in regulating host response to viral and bacterial infections. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. [provided by RefSeq, Aug 2020]
Tag	Free
Gene ID	6774
Synonyms	STAT3; APRF; Signal transducer and activator of transcription 3; Acute-phase response factor
Molecular Weight	Predicted band size: 88 kDa
Purity	affinity purified
Conjugation	Non-conjugated
Research Field	Signal Transduction
Product Categories	Primary Antibody; Rabbit Polyclonal Antibody
Host	Rabbit
Reactivity	Human, Mouse, Rat
SwissProt ID	P40763
Dilution Ratio	WB: 1:500-1:1,000 ;IHC: 1:50-1:100 ;IF: 1:50-1:200 ;IP: 1:20
Application	WB, IHC-P, ICC/IF, IP
Appearance	Liquid
Formulation	Supplied in phosphate buffered saline (pH 7.4), 150 mM NaCl and 50% glycerol. Preservative: 0.02% sodium azide
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG
Immunogen	Synthetic phosphopeptide corresponding to residues surrounding Tyr705 of Human STAT3.The exact sequence is proprietary to MCE.
Documentation	Select Batch: Data Sheet (235 KB) SDS (0 KB) COA (205 KB) User Guide for Antibodies (1077 KB)

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Phospho-STAT3 (Tyr705) Antibody

Biological Activity

Technical Parameters

Properties

Documentation

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