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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
272 Results for "
human hepatocyte
" in MedChemExpress (MCE) Product Catalog:
Products (272)
272 Results for "human hepatocyte" in MCE Product Catalog:
9
9
9 Publications Verification
Cat. No.: HY-N2334A
CAS No.: 16564-43-5
Synonyms: Chenodeoxycholylglycine sodium salt; Sodium glycochenodeoxycholate
6
6 Cited Publications
Cat. No.: HY-P7121
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HGF; hepatocyte Growth Factor (Hepapoietin A; Scatter Factor); Prev. DFNB39; Lung Fibroblast-Derived Mitogen; HPTA; Hepatopoietin-A; SF; Scatter Factor; F-TCF; Deafness, Autosomal Recessive 39; HGFB; Hepatopoietin A; hepatocyte Growth Factor; Fibroblast-D
Species:
Human
Source:
CHO
5
5 Cited Publications
Cat. No.: HY-P7049
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LIF; hepatocyte-Stimulating Factor III; LIF Interleukin 6 Family Cytokine; Differentiation-Inducing Factor; HILDA; Melanoma-Derived LPL Inhibitor; Leukemia Inhibitory Factor; human Interleukin In DA Cells; CDF; D Factor; DIA; MLPLI; Differentiation Inhibi
Species:
Human
Source:
E. coli
5
5 Cited Publications
Cat. No.: HY-P7084
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LIF; hepatocyte-Stimulating Factor III; LIF Interleukin 6 Family Cytokine; Differentiation-Inducing Factor; HILDA; Melanoma-Derived LPL Inhibitor; Leukemia Inhibitory Factor; human Interleukin In DA Cells; CDF; D Factor; DIA; MLPLI; Differentiation Inhibi
Species:
Mouse
Source:
E. coli
4
4 Cited Publications
Cat. No.: HY-P73276
Purity: ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: LIF; hepatocyte-Stimulating Factor III; LIF Interleukin 6 Family Cytokine; Differentiation-Inducing Factor; HILDA; Melanoma-Derived LPL Inhibitor; Leukemia Inhibitory Factor; human Interleukin In DA Cells; CDF; D Factor; DIA; MLPLI; Differentiation Inhibi
Species:
Human
Source:
HEK293
3
3 Cited Publications
Synonyms: Chlorguanide triazine hydrochloride
Target:
Cycloguanil (Chlorguanide triazine) hydrochloride is a dihydrofolate reductase (DHFR) inhibitor with an IC50 of 10.8 μM against human DHFR. Cycloguanil hydrochloride blocks the folate metabolic pathway, thereby affecting nucleotide synthesis and interfering with DNA replication. Cycloguanil inhibits DHFR in Plasmodium and is thus used in malaria research. Cycloguanil hydrochloride also potently inhibits DHFR in human cancer cells and blocks the transcriptional activity of STAT3, thereby exhibiting anticancer activity .
3
Target:
Research Areas:
Benzamidine is a competitive protease inhibitor that blocks the hydrolytic cleavage of glucagon by plasmin, trypsin and thrombin. Benzamidine effectively inhibits the degradation of glucagon by relevant proteases during the collection, storage and analysis of human plasma and blood samples. During in vivo metabolism, Benzamidine undergoes N-hydroxylation and produces multiple metabolites, exhibiting characteristics of delayed excretion or biphasic elimination. Benzamidine only induces slight single-strand DNA breaks at high concentrations and shows no significant genotoxic potential overall. Benzamidine may interfere with the detection of some glucagon antisera, but does not affect key antigen-antibody affinity at specific concentrations. Benzamidine can be used as a stabilizer in glucagon radioimmunoassays to ensure the accuracy and recovery rate of detection results .
2
2 Cited Publications
Target:
Research Areas:
KDM4C-IN-1 is a histone lysine demethylase KDM4C inhibitor with an IC50 of 8 nM. KDM4C-IN-1 inhibits cancer cell proliferation. KDM4C-IN-1 can be used in the research of hepatocellular carcinoma and adenocarcinoma alveolar basal epithelial carcinoma .
2
2 Cited Publications
Cat. No.: HY-P70627
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HGF; hepatocyte Growth Factor (Hepapoietin A; Scatter Factor); Prev. DFNB39; Lung Fibroblast-Derived Mitogen; HPTA; Hepatopoietin-A; SF; Scatter Factor; F-TCF; Deafness, Autosomal Recessive 39; HGFB; Hepatopoietin A; hepatocyte Growth Factor; Fibroblast-D
Species:
Human
Source:
HEK293
2
Research Areas:
Omeprazole sulfone (Omeprazole sulphone) is one of the major circulating metabolites of Omeprazole (HY-B0113) in vivo, and belongs to class 4 non-mutagenic impurities. Omeprazole sulfone does not bind to the aryl hydrocarbon receptor (AhR), nor does it induce the expression of CYP1A1 or CYP1A2. However, Omeprazole sulfone promotes the migration of gastric epithelial cells under basal conditions and reverses the inhibitory effect of Indomethacin (HY-14397) on cell migration. Omeprazole sulfone does not promote cell proliferation, nor does it upregulate COX-2 expression or activate signaling pathways such as ERK, P38 MAPK and PI3K. Omeprazole sulfone maintains basal ulcer healing under non-acid-dependent conditions and can be used in studies related to gastric ulcer repair .
2
Research Areas:
Omeprazole sulfide (Ufiprazole) is a metabolic degradation product of Omeprazole (HY-B0113). Omeprazole sulfide acts as a modulator of AhR. Omeprazole sulfide in cells with low CYP3A4 expression, functions as an AhR antagonist; however, in cells with high CYP3A4 expression, it is rapidly metabolized to Omeprazole, thereby acting as an AhR agonist. Omeprazole sulfide exhibits antibacterial activity when conjugated with silver nanoparticles (AgNPs). Omeprazole sulfide can be used in research on acid suppression and bacterial infections .
2
2 Cited Publications
Cat. No.: HY-P70832
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HABP2; Factor VII Activating Protein; Hyaluronan Binding Protein 2; Hyaluronan-Binding Protein 2; HGFAL; FVII Activator; PHBP; PHBSP; FSAP; Hyaluronic Acid Binding Protein 2; HABP; Plasma Hyaluronan-Binding Protein; hepatocyte Growth Factor Activator-Like
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-W286743
CAS No.: 5746-04-3
Synonyms: CML; N6-(Carboxymethyl)-L-lysine; Nε-(1-Carboxymethyl)-L-lysine
1
1 Cited Publications
Cat. No.: HY-155108B
Purity: 99.88%
OATD-02 hydrochloride is the hydrochloride salt form of OATD-02 (HY-155108). OATD-02 hydrochloride an orally active, competitive, reversible, noncovalent dual inhibitor of Arginase1 and Arginase2. OATD-02 hydrochloride is a slow offset inhibitor, blocking intracellular arginases with IC50s of 20 nM (hARG1), 39 nM (hARG2), 39 nM (mARG1), and 28 nM (rARG1), respectively. OATD-02 hydrochloride bolishes tumor immunosuppression induced by both arginases. OATD-02 hydrochloride can be used for melanoma study .
1
1 Cited Publications
Target:
Research Areas:
PF-06649298 is a sodium-coupled citrate transporter (NaCT or SLC13A5) inhibitor. PF-06649298 specifically interacts with NaCT with an IC50 value of 16.2 μM to inhibits the transport of citrate in human hepatocytes. PF-06649298 can be used for the research of regulating glucose metabolism and lipid metabolism .
1
1 Cited Publications
Cat. No.: HY-P701139A
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HNF4A; TCF-14; Prev. TCF14; hepatocyte Nuclear Factor 4 4 Alpha Variant 4; Prev. MODY1; hepatocyte Nuclear Factor 4 4 Alpha Variant 1; Prev. MODY; hepatocyte Nuclear Factor 4 4 Alpha Variant 2; NR2A1; Truncated hepatocyte Nuclear Factor 1 Alpha; HNF4; HNF
Species:
Human
Source:
HEK293
1
1 Cited Publications
Synonyms: Tris HCl (≥99%, for cell culture); Tris hydrochloride (≥99%, for cell culture)
1
1 Cited Publications
Cat. No.: HY-P78324
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: LIF; hepatocyte-Stimulating Factor III; LIF Interleukin 6 Family Cytokine; Differentiation-Inducing Factor; HILDA; Melanoma-Derived LPL Inhibitor; Leukemia Inhibitory Factor; human Interleukin In DA Cells; CDF; D Factor; DIA; MLPLI; Differentiation Inhibi
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P72267
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MET; Soluble MET Variant 13; MET Proto-Oncogene, Receptor Tyrosine Kinase; Soluble MET Variant 14; hepatocyte Growth Factor Receptor; Soluble MET Variant 15; DFNB97; Soluble MET Variant 1; RCCP2; Soluble MET Variant 2; HGFR; Soluble MET Variant 3; Tyrosin
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
