2-Me PeER
2-Me PeER is a rhodamine dye-based fluorescent probe that detects CYP3A4 activity. In fluorescence-activated cell sorting (FACS) based on CYP3A4 activity, homogeneous and functional human induced pluripotent stem cell (hiPSC)-derived hepatocytes and intestinal epithelial cells can be obtained with the aid of 2-Me PeER.
For research use only. We do not sell to patients.
- Formula: C31H37N2O4+
- Molecular Weight:501.64
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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Molecular Weight 501.64
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Formula C31H37N2O4+
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SMILES
O=C(O)C(C=CC=C1)=C1C2=C(C=C/3)C(OC4=C2C=C(C)C(N(CCOCCCCC)C)=C4)=CC3=[N+](C)/C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Fluorescence activated cell sorting
Fluorescence activated cell sorting (FACS) is a special technology for identifying and separating rare cell populations with high purity.
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Fluorescence-Activated Cell Sorting (FACS)-Based Cell Sorting
Fluorescence-Activated Cell Sorting (FACS) separates cells in suspension after flow-cytometric measurement of light scatter and fluorescence; classic droplet-based instruments interrogate cells with a laser, convert optical signals into electronic signals, charge droplets containing target cells, and electrostatically deflect them into collection vessels. FACS detects phenotypes defined by fluorescent antibodies, fluorescent proteins, viability dyes, or intracellular markers, and the readout is the sorted fraction, purity, recovery, and post-sort viability of the gated population.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)