Phenothrin (Standard)
Phenothrin (Standard) is the analytical standard of Phenothrin (HY-B1072). This product is intended for research and analytical applications. Phenothrin is a voltage-gated sodium channel modulator. Phenothrin mainly acts on sodium channels in the closed resting state, slows their opening and closing, increases the steady-state sodium current, and prolongs the sodium current through slowly decaying tail currents. Phenothrin induces dose-dependent DNA damage and oxidative DNA damage in human peripheral blood lymphocytes and human hepatocytes. Phenothrin is used as an insecticide for agricultural, household, and public health insect control and for eliminating human lice infestations.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 26002-80-2
- 分子式: C23H26O3
- 分子量:350.45
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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化学情報
- 純度とドキュメンテーション
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Help & FAQs
Product Information
説明
アプリケーション
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
化学情報
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CAS 番号 26002-80-2
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分子量 350.45
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分子式 C23H26O3
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SMILES
O=C(C1C(C)(C)C1/C=C(C)\C)OCC2=CC=CC(OC3=CC=CC=C3)=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Nagy K, et al. Evaluation of the genotoxicity of the pyrethroid insecticide phenothrin. Mutat Res Genet Toxicol Environ Mutagen. 2014;770:1-5. [Content Brief]
[2]. de Weille JR, et al. Interactions of pyrethroids and octylguanidine with sodium channels of squid giant axons. Brain research. 1988 Mar 29;445(1):1-11. [Content Brief]
[3]. Ruigt GS, et al. Increase of sodium current after pyrethroid insecticides in mouse neuroblastoma cells. Brain research. 1987 Dec 29;437(2):309-22. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Phenothrin (Standard) 関連分類
HY-B1072R 関連分類
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Keywords
- Phenothrin (Standard)
- 26002-80-2
- Reference Standards
- Environmental Pollutants
- Parasite
- Insecticide
- Sodium Channel
- DNA damage
- HepG2 hepatoblastoma cells
- genotoxin
- human hepatocytes
- human peripheral blood lymphocytes
- insecticide
- louse infestation
- oxidative DNA damage
- squid giant axons
- voltage-gated sodium channel
- Inhibitor
- inhibitor
- inhibit