HBV-IN-29
HBV-IN-29 (ex8), a flavone derivative, is a potent covalently closed circular DNA (cccDNA) inhibitor. cccDNA serves as the template for viral RNA transcription and subsequent viral DNA generation. HBV-IN-29 has the potential for the research of HBV infection.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2413192-59-1
- 分子式: C22H19ClO6
- 分子量:414.84
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体外実験
HBV-IN-29 (ex8; 24 h) inhibits HBeAg levels and cell viability with an IC50 value of 1.34 μM in HepDES19 cells. HepDES19 is the cell line that produces cccDNA[1].
HBV-IN-29 (5 days) decreases cccDNA levels in HepDES19 cells in a dose-dependent manner[1].
HBV-IN-29 (9 days; primary human hepatocyte (PHH)) has anti-HBV effect and inhibits HBeAg with an IC50 value of 0.12 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2413192-59-1
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分子量 414.84
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分子式 C22H19ClO6
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SMILES
O=C(O)COC1CC(COC2=CC=C(C3=CC(C4=CC=CC(Cl)=C4O3)=O)C=C2)C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
HBV-IN-29 関連分類
HY-148780 関連分類
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