2. Protein Tyrosine Kinase/RTK Immunology/Inflammation
  3. Src Interleukin Related
  4. Lck-IN-6

Lck-IN-6 (Compound 12g) is a Lck inhibitor with an IC50 of 3 nM. Lck-IN-6 inhibits the production of IL-2. Lck-IN-6 can be used in the research of rheumatoid arthritis and inflammatory bowel disease.

For research use only. We do not sell to patients.

Lck-IN-6

Lck-IN-6 Chemical Structure

CAS No. : 918870-43-6

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Lck-IN-6 Related Antibodies

Top Publications Citing Use of Products

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Lck Fyn Blk Fgr Hck Lyn Yes SRC-3

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IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22 IL-18

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Description

Lck-IN-6 (Compound 12g) is a Lck inhibitor with an IC50 of 3 nM. Lck-IN-6 inhibits the production of IL-2. Lck-IN-6 can be used in the research of rheumatoid arthritis and inflammatory bowel disease[1].

IC50 & Target[1]

Lck

3 nM (IC50)

In Vitro

Lck-IN-6 inhibits recombinant human active Lck with an IC50 of 3 nM[1].
Lck-IN-6 inhibits IL-2 production in stimulated Jurkat E6-1 human acute T cell leukemia cells with an IC50 of 0.054 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Lck-IN-6 Related Antibodies
Molecular Weight

446.51

Formula

C24H26N6O3
CAS No.
SMILES

OC1=CC=C(C(=C1)NC2=NC(=NC(OCCN3CCOCC3)=C2)N4C=NC=5C=CC=CC54)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Lck-IN-6 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lck-IN-6918870-43-6SrcInterleukin RelatedILLymphocyte specific kinasecryopreserved rat hepatocyte suspensionsIL-2interleukin-2Lckinflammatory bowel diseaseJurkat E6-1 human acute T cell leukemia cellsrheumatoid arthritissystemic lupus erythematosuspsoriasisInhibitorinhibitorinhibit

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Lck-IN-6
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HY-112448
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