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Glucosylceramide synthase-IN-4

Glucosylceramide synthase-IN-4 (compound 12) is a potent glucosylceramide synthase (GCS) inhibitor, with an IC50 of 6.8 nM. Glucosylceramide synthase-IN-4 shows excellent PK properties and stability in human hepatocytes. Glucosylceramide synthase-IN-4 has good CNS penetration and acceptable PXR selectivity.

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  • CAS No.: 2776965-41-2
  • Formula: C22H18F5N3O3
  • Molecular Weight:467.39
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Glucosylceramide synthase-IN-4 Chemical Structure
    Glucosylceramide synthase-IN-4 Chemical Structure
CAS No.: 2776965-41-2
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  • Glucosylceramide synthase-IN-4 Chemical Structure
    Glucosylceramide synthase-IN-4 Chemical Structure
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  • Glucosylceramide synthase-IN-4