1. Natural Products
  2. Plants Terpenoids
  3. Phytolaccaceae Pentacyclic Triterpenoids
  4. Phytolacca americana L.
  5. Esculentoside L

Esculentoside L is a triterpene saponin present in the roots of Phytolacca americana. Esculentoside L increases the intracellular accumulation of calcein in multidrug-resistant human ovarian cancer cells. Esculentoside L exerts no significant cytotoxic activity against non-cancerous cells and hepatocytes. Esculentoside L can be used in studies related to multidrug-resistant human ovarian cancer.

For research use only. We do not sell to patients.

Esculentoside L

Esculentoside L Chemical Structure

CAS No. : 130364-33-9

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Description

Esculentoside L is a triterpene saponin present in the roots of Phytolacca americana. Esculentoside L increases the intracellular accumulation of calcein in multidrug-resistant human ovarian cancer cells. Esculentoside L exerts no significant cytotoxic activity against non-cancerous cells and hepatocytes. Esculentoside L can be used in studies related to multidrug-resistant human ovarian cancer[1].

In Vitro

Esculentoside L (0.25-25 μg/mL) increases calcein accumulation in multidrug-resistant human ovarian cancer cell line 2780AD[1].
Esculentoside L shows no significant cytotoxicity against WI-38, VA-13, HepG2 and A549 cells, with its IC50 values all greater than 103 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

973.11

Formula

C48H76O20

CAS No.
SMILES

C[C@@]1(C(OC)=O)CC[C@]2(C(O[C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O3)=O)CC[C@]4(C)C([C@H]2C1)=CC[C@H]5[C@@]4(C)CCC6[C@]5(C)CC[C@H](O[C@H]7[C@H](O)[C@@H](O)[C@H](O[C@H]8[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O8)CO7)[C@]6(CO)C

Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Esculentoside L
Cat. No.:
HY-N18168
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