1. Anti-infection
    Metabolic Enzyme/Protease
  2. Parasite
    Drug Metabolite
  3. Cycloguanil hydrochloride

Cycloguanil hydrochloride 

Cat. No.: HY-12784A Purity: 99.83%
Handling Instructions

Cycloguanil hydrochloride, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes.

For research use only. We do not sell to patients.

Cycloguanil hydrochloride Chemical Structure

Cycloguanil hydrochloride Chemical Structure

CAS No. : 152-53-4

Size Price Stock Quantity
10 mM * 1  mL in DMSO USD 158 In-stock
Estimated Time of Arrival: December 31
5 mg USD 90 In-stock
Estimated Time of Arrival: December 31
10 mg USD 150 In-stock
Estimated Time of Arrival: December 31
25 mg USD 250 In-stock
Estimated Time of Arrival: December 31
50 mg USD 450 In-stock
Estimated Time of Arrival: December 31
100 mg USD 750 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Cycloguanil hydrochloride:

Top Publications Citing Use of Products
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Description

Cycloguanil hydrochloride, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes[1].

Molecular Weight

288.18

Formula

C₁₁H₁₅Cl₂N₅

CAS No.

152-53-4

SMILES

NC1=NC(N)=NC(C)(N1C2=CC=C(C=C2)Cl)C.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (216.88 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4701 mL 17.3503 mL 34.7005 mL
5 mM 0.6940 mL 3.4701 mL 6.9401 mL
10 mM 0.3470 mL 1.7350 mL 3.4701 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (7.22 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (7.22 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (7.22 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

CycloguanilParasiteDrug MetaboliteInhibitorinhibitorinhibit

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Product name:
Cycloguanil hydrochloride
Cat. No.:
HY-12784A
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