Glycochenodeoxycholic acid (Standard)
Based on 1 Customer Validation
Glycochenodeoxycholic acid (Standard) is the analytical standard of Glycochenodeoxycholic acid. This product is intended for research and analytical applications. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a relatively toxic bile salt generated in the liver from chenodeoxycholic acid and glycine. Glycochenodeoxycholic acid inhibits Autophagosome formation and impairs lysosomal function by inhibiting lysosomal proteolysis and increasing lysosomal pH in human normal liver cells, leading to the Apoptosis of human hepatocyte cells. Glycochenodeoxycholic acid induces stemness and chemoresistance via activating STAT3 signaling pathway in hepatocellular carcinoma cells (HCC). Glycochenodeoxycholic acid is promising for research in the field of cholestasis desease, hepatocellular carcinoma and primary sclerosing cholangitis (PSC)[1][2][3][4].
For research use only. We do not sell to patients.
- Purity : 99.77%
- CAS No.: 640-79-9
- Formula: C26H43NO5
- Molecular Weight:449.62
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
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Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 640-79-9
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Appearance Solid
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Molecular Weight 449.62
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Formula C26H43NO5
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Color White to off-white
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SMILES
C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(NCC(O)=O)=O)([H])[C@@]3([H])[C@]([C@@]4([C@](C[C@H](O)CC4)([H])C[C@H]3O)C)([H])CC1
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Synonyms
Chenodeoxycholylglycine (Standard)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Glycochenodeoxycholic acid (Standard) Related Classifications
HY-N2334R Related Classifications
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Keywords
- Glycochenodeoxycholic acid (Standard)
- 640-79-9
- Chenodeoxycholylglycine (Standard)
- Reference Standards
- Interleukin Related
- Apoptosis
- STAT
- Endogenous Metabolite
- Caspase
- BCL6
- IL
- B-cell lymphoma 6 protein
- B-cell lymphoma 5 protein (BCL-5)
- Zinc finger and BTB domain-containing protein 27
- Zinc finger protein 51
- bile salt
- hepatocellular carcinoma cells
- autophagosome inhibition
- STAT3 signaling pathway
- cholestasis desease
- primary sclerosing cholangitis
- Inhibitor
- inhibitor
- inhibit