Citrusinol
Citrusinol is a natural product isolated from D. caudatum. Citrusinol has anticancer activity and inhibits the proliferation and migration of human hepatocytes HepG 2.
For research use only. We do not sell to patients.
- CAS No.: 112516-43-5
- Formula: C20H16O6
- Molecular Weight:352.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
43.3 μM
Compound: citrusinol
|
Cytotoxicity against human HepG2 cells by MTT assay
Cytotoxicity against human HepG2 cells by MTT assay
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[PMID: 15921433] |
| KB | IC50 |
42.3 μM
Compound: citrusinol
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Cytotoxicity against human KB cells by MTT assay
Cytotoxicity against human KB cells by MTT assay
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[PMID: 15921433] |
Chemical Information
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CAS No. 112516-43-5
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Molecular Weight 352.34
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Formula C20H16O6
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SMILES
O=C1C2=C(O)C=C3C(C=CC(C)(C)O3)=C2OC(C4=CC=C(O)C=C4)=C1O
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell migration
Cell migration is a method that plays an important role in wound healing, cell differentiation, embryonic development, etc.
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Cell Viability Determination by MTT Colorimetric Assay
The following protocol uses the MTT colorimetric assay as a classic literature-established method for assessing cell viability/metabolic activity in cultured mammalian cells. MTT[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] is reduced by metabolically active cells to a colored formazan product; the amount of formazan is quantified spectrophotometrically and provides an indirect measure of metabolically active viable cells. Importantly, MTT reduction reflects cellular oxidoreductase/metabolic activity rather than an absolute direct count of living cells, so changes in cellular metabolism can alter the signal independently of cell number.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Citrusinol Related Classifications
HY-N7790 Related Classifications
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