Diacylglycerol acyltransferase inhibitor-2
Diacylglycerol acyltransferase inhibitor-2 (Example 8) is an inhibitor of Diacylglycerol Acyl Transferase 2 (DGAT2) with an IC50 value of 3.7 nM.
For research use only. We do not sell to patients.
- CAS No.: 2186700-48-9
- Formula: C21H20FN5O4
- Molecular Weight:425.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
IC50:3.7 nM (DGAT2)[1].
Chemical Information
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CAS No. 2186700-48-9
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Molecular Weight 425.41
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Formula C21H20FN5O4
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SMILES
FC1=CN=C(OC2=CN=CC(C3=NC=C(C(N[C@@H]4COCC4)=O)C=N3)=C2)C(OCC)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Diacylglycerol acyltransferase inhibitor-2 Related Classifications
HY-162854 Related Classifications
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