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Results for "

pathogen

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aminoacyl-tRNA Synthetase (1) Antibiotic (48) Apoptosis (4) Autophagy (2) Bacterial (124) Beta-lactamase (6) Biochemical Assay Reagents (2) c-Myc (1) CMV (1) Dengue virus (3) DNA/RNA Synthesis (2) Endogenous Metabolite (7) Fatty Acid Synthase (FASN) (1) Filovirus (2) Flavivirus (3) Fluorescent Dye (1) Fungal (32) HCV (3) HIV (7) HSV (2) Influenza Virus (6) Isotope-Labeled Compounds (4) Liposome (1) MAP4K (1) Mitochondrial Metabolism (1) Orthopoxvirus (2) p62 (2) Parasite (6) Phosphatase (1) Phospholipase (1) PKC (1) PPAR (1) Reactive Oxygen Species (2) SARS-CoV (2) Sirtuin (1) STING (1) TNF Receptor (1) TOPK (2) Topoisomerase (2)
By Research Areas:	Cancer (17) Infection (146) Inflammation/Immunology (21) Metabolic Disease (1) Neurological Disease (1)

By Targets:

Aminoacyl-tRNA Synthetase (1)

Antibiotic (48)

Apoptosis (4)

Autophagy (2)

Bacterial (124)

Beta-lactamase (6)

Biochemical Assay Reagents (2)

c-Myc (1)

CMV (1)

Dengue virus (3)

DNA/RNA Synthesis (2)

Endogenous Metabolite (7)

Fatty Acid Synthase (FASN) (1)

Filovirus (2)

Flavivirus (3)

Fluorescent Dye (1)

Fungal (32)

HCV (3)

HIV (7)

HSV (2)

Influenza Virus (6)

Isotope-Labeled Compounds (4)

Liposome (1)

MAP4K (1)

Mitochondrial Metabolism (1)

Orthopoxvirus (2)

p62 (2)

Parasite (6)

Phosphatase (1)

Phospholipase (1)

PKC (1)

PPAR (1)

Reactive Oxygen Species (2)

SARS-CoV (2)

Sirtuin (1)

STING (1)

TNF Receptor (1)

TOPK (2)

Topoisomerase (2)

By Research Areas:

Cancer (17)

Infection (146)

Inflammation/Immunology (21)

Metabolic Disease (1)

Neurological Disease (1)

183

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-155333

Antibiofilm agent-1

Bacterial Infection

Antibiofilm agent-1 is an antibacterial agent that inhibits growth of Gram-positive pathogens (WO2017011725A1; compound 17) .

Antibiofilm agent-1	Bacterial	Infection
Antibiofilm agent-1 is an antibacterial agent that inhibits growth of Gram-positive pathogens (WO2017011725A1; compound 17) .

HY-144093

HPK1-IN-26	MAP4K	Infection
HPK1-IN-26 is a HPK1 and GLK inhibitor extracted from patent WO2021254118A1 compound 1. HPK1-IN-26 can be used for the research of animal pathogen infection .

HY-139748

ETX0462	Antibiotic Bacterial	Infection
ETX0462 is a gram-negative chemotype antibiotic. ETX0462 has potent in vitro and in vivo activity against Pseudomonas aeruginosa plus all other Gram-negative ESKAPE pathogens, Stenotrophomonas maltophilia and biothreat pathogens .

HY-W008927A

(Z)-Fluoxastrobin

Fungal Infection

(Z)-Fluoxastrobin is fungicide agent. (Z)-Fluoxastrobin has excellent control of important seed and soilborne pathogens .

(Z)-Fluoxastrobin	Fungal	Infection
(Z)-Fluoxastrobin is fungicide agent. (Z)-Fluoxastrobin has excellent control of important seed and soilborne pathogens .

HY-126869

Pseudomonic acid D	Bacterial Parasite	Infection
Pseudomonic acid D is a microbial inhibitor. Pseudomonic acid D potently inhibits mycoplasmas and bacterial pathogens. Pseudomonic acid D can be produced by fermentation with Pseudomonas fluorescens .

HY-B0925

Oxacillin sodium salt 5+ Cited Publications	Bacterial Antibiotic	Infection
Oxacillin sodium salt is an orally active synthetic penicillin with good bactericidal activity against staphylococci and other gram-positive pathogens .

HY-N10584

Malacidin A	Antibiotic Bacterial	Infection
Malacidin A is the calcium-dependent antibiotic (CDAs). Malacidin A is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria .

HY-W009886

3,4,5-Trimethoxybenzaldehyde	Bacterial	Infection
3,4,5-Trimethoxybenzaldehyde is an intermediate for the synthesis of various pharmaceuticals, especially for trimethoprim used to research bacterial infections, including urinary tract pathogens infection.

HY-N5124

Meloside A 1 Publications Verification Isovitexin 2''-O-glucoside; Isovitexin 2''-O-β-D-glucoside	Others	Infection
Meloside A (Isovitexin 2''-O-glucoside) is a phenylpropanoid isolated from barley with antioxidant activity. In barley, phenylpropanoids have been described as having protective properties against excess UV-B radiation and have been linked to resistance to pathogens .

HY-126604

Pyranonigrin A	Others	Infection
Pyranonigrin A is isolated and identified from Penicillium brocae MA-231. Pyranonigrin A shows potent activity against a broad spectrum of human-, aqua-, and plant-pathogens .

HY-124801

ABMA	Flavivirus Dengue virus Bacterial Parasite	Infection
ABMA is a broad-spectrum inhibitor of intracellular toxins and pathogens. ABMA efficiently protects cells against various toxins and pathogens including viruses, intracellular bacteria and parasite. ABMA selectively acts at host cell late endosomes rather than targeting toxin or pathogen itself. ABMA has broad-spectrum anti-infection activity .

HY-N12262

(+)-Epieudesmin	Bacterial	Infection Cancer
(+)-Epieudesmin is an antineoplastic agent. (+)-Epieudesmin has marginal cancer cell line inhibitory activities. (+)-Epieudesmin inhibits the growth of Gram-negative pathogen .

HY-W018025

5,6-Dihydroxyindole	Bacterial Fungal Parasite Endogenous Metabolite	Infection Inflammation/Immunology
5,6-Dihydroxyindole, a melanin precursor, has a broad-spectrum antibacterial, antifungal, antiviral, antiparasitic activity. 5,6-Dihydroxyindole has cytotoxic effects and is strongly toxic against various pathogens .

HY-136613

Demethyl linezolid	Bacterial	Infection
Demethyl linezolid is a impurity of linezolid. Demethyl linezolid is a useful antimicrobial agent extracted from patent WO1995007271A1, example 9, effective against a number of human and veterinary pathogens .

HY-16158

Cyclacillin Wy-4508; Aminocyclohexylpenicillin; Ciclacillin	Bacterial Antibiotic	Infection
Cyclacillin (Wy-4508) is an orally active aminopenicillin antibiotic, shows antibacterial activity against a wide range of gram-positive and gram-negative pathogens .

HY-144300

Rifasutenizol TNP-2198	Bacterial	Infection
Rifasutenizol (TNP-2198) is a potent and orally bioavailable dual-targeted antibacterial agent. Rifasutenizol has potent activity against microaerophilic and anaerobic bacterial pathogens .

HY-W008833

3-Aminobutanoic acid	Bacterial	Infection
3-Aminobutanoic acid is a β-amino acid. 3-Aminobutanoic acid can protect plant against a challenge infection with P. infestans. 3-Aminobutanoic acid has various levels of susceptibility for the pathogen .

HY-151918

Antibacterial agent 125	Bacterial	Infection Inflammation/Immunology
Antibacterial agent 125 is an antibacterial agent. Antibacterial agent 125 has a potent antimicrobial activity against clinically relevant Gram-positive pathogens with MIC₅₀ values range from 0.25 - 8 μM. Antibacterial agent 125 can be used for the research of antimicrobial resistance .

HY-12479A

Epetraborole hydrochloride 2 Publications Verification GSK2251052 hydrochloride	Bacterial Aminoacyl-tRNA Synthetase	Infection
Epetraborole (GSK2251052) hydrochloride is a novel leucyl-tRNA synthetase (LeuRS) inhibitor (IC₅₀=0.31 μM), thereby inhibiting protein synthesis. Epetraborole hydrochloride can be used in multidrug-resistant gram-negative pathogens infection research .

HY-N7001

Dehydrotomatine	Bacterial Fungal	Infection
Dehydrotomatine is a steroidal glycoalkaloid (SGA). α-tomatine and Dehydrotomatine accumulate in the mature green fruits, leaves, and flowers of tomatoes (Solanum lycopersicum) and function as defensive compounds against pathogens and predators. SGAs show toxic effects on fungi, bacteria, insects, and animals .

HY-B0322A

Sulfamethoxazole sodium Ro 4-2130 sodium	Bacterial Antibiotic	Infection
Sulfamethoxazole sodium (Ro 4-2130 sodium) is a sulfonamide bacteriostatic antibiotic . Sulfamethoxazole sodium is used to treat various urinary tract pathogens and in combination with Trimethoprim is considered the gold standard in the treatment of urinary tract infections (UTIs) .

HY-A0279

Pristinamycin Pristinamycine	Bacterial Antibiotic	Infection
Pristinamycin, produced by Streptomyces pristinaespiralis, is an orally active streptogramin-like antibiotic consisting of two chemically unrelated components: Pristinamycin I (PI) and Pristinamycin II (PII). Pristinamycin is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant S. aureus (VRSA) and Enterococcus faecium (VREF) .

HY-155461

Antibiofilm agent-3	Bacterial	Infection
Antibiofilm agent-3 (compound 3b) is a tetracarboxamide antibacterial agent that effectively inhibits the plant bacterial pathogen Xanthomonas citri (Xanthomonas citri ssp. citri, Xcc) (MIC=500 μg/ mL). Antibiofilm agent-3 inhibits biofilm formation by Xcc with IC₅₀=15.37 μg/mL .

HY-P3350

LS-BF1	Bacterial	Infection
LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].

HY-118149A

(±)9-HpODE	Bacterial Fungal Parasite	Infection
(±)9-HpODE is a long chain lipid hydroperoxide, is a product of linoleic acid peroxidation. (±)9-HpODE can induce oxidation of intracellular glutathione (GSH). (±)9-HpODE also exhibits antimicrobial activity against various fungal and bacterial pathogens .

HY-B0536

Clinafloxacin AM-1091; CI-960; PD 127391	Bacterial Antibiotic	Infection
Clinafloxacin (AM 1091) is a potent and broad-spectrum fluoroquinolone antibiotic, has inhibitory activity against gram-positive, gram-negative bacterias, and anaerobic pathogens in vitro . Clinafloxacin is against DNA gyrase and topoisomerase IV of S. aureus with IC₅₀ values of 0.92 µg/ml and 1.62 µg/ml, respectively .

HY-B0536A

Clinafloxacin hydrochloride AM 1091 hydrochloride; CI 960 hydrochloride; PD127391 hydrochloride	Bacterial Antibiotic	Infection
Clinafloxacin hydrochloride (AM 1091 hydrochloride) is a potent and broad-spectrum fluoroquinolone antibiotic, has inhibitory activity against gram-positive, gram-negative bacterias, and anaerobic pathogens in vitro . Clinafloxacin hydrochloride is against DNA gyrase and topoisomerase IV of S. aureus with IC₅₀ values of 0.92 µg/ml and 1.62 µg/ml, respectively .

HY-N10572

Antibacterial synergist 2	Bacterial	Infection
Antibacterial synergist 2 (compound 27) is a biofilm inhibitor. Antibacterial synergist 2 shows inhibitory effects to S. enterica, S. aureus, P. aeruginosa and C. albicans. Antibacterial synergist 2 can be used for the research related to biofilm-forming pathogens .

HY-161395

IDD-8E	Bacterial	Infection
IDD-8E is an effective anti-pseudomonal agent (MIC =4.4 µM ) with no cytotoxicity. IDD-8E shows significant pseudomonal killing and disruption of pseudomonal biofilm. IDD-8E binds to the ATP-binding pocket of WaaP and also inhibits other ESKAPE pathogens.

HY-139554

Zifanocycline KBP-7072	Bacterial	Infection
Zifanocycline (KBP-7072) is a semisynthetic third-generation aminomethylcycline antibiotic that inhibits the normal function of the bacterial ribosome. Zifanocycline exhibits a broad spectrum of in vitro antibacterial activity against Gram-positive and Gram-negative bacteria, including many multidrug-resistant pathogens. Zifanocycline is available in both oral and injectable formulations. Zifanocycline can be used for the research of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections .

HY-N7378

N-Hydroxypipecolic acid 2 Publications Verification 1-Hydroxy-2-piperidinecarboxylic acid; NHP	Bacterial	Inflammation/Immunology
N-Hydroxypipecolic acid (1-Hydroxy-2-piperidinecarboxylic acid), a plant metabolite and a systemic acquired resistance (SAR) regulator, orchestrates SAR establishment in concert with the immune signal salicylic acid. N-Hydroxypipecolic acid accumulates systemically in the plant foliage in response to pathogen attack. N-Hydroxypipecolic acid induces SAR to bacterial and oomycete infection .

HY-N7378A

N-Hydroxypipecolic acid potassium 1-Hydroxy-2-piperidinecarboxylic acid potassium; NHP potassium	Bacterial	Inflammation/Immunology
N-Hydroxypipecolic acid potassium (1-Hydroxy-2-piperidinecarboxylic acid potassium), a plant metabolite and a systemic acquired resistance (SAR) regulator, orchestrates SAR establishment in concert with the immune signal salicylic acid. N-Hydroxypipecolic acid potassium accumulates systemically in the plant foliage in response to pathogen attack. N-Hydroxypipecolic acid potassium induces SAR to bacterial and oomycete infection .

HY-148420

CDN-A	STING	Inflammation/Immunology
CDN-A is a cyclic di-nucleotide, it can be used to synthesis antibody-drug conjugate (ADC). Cyclic di-nucleotides are potent stimulators of innate and adaptive immune responses. In humans, cyclic di-nucleotide, which are either produced endogenously in response to foreign DNA or by invading bacterial pathogens, trigger the innate immune system by activating the expression of interferon genes .

HY-112579

Ceftobiprole 2 Publications Verification Ro 63-9141; BAL 9141	Bacterial Antibiotic	Infection Inflammation/Immunology
Ceftobiprole (Ro 63-9141) is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci with a MIC₉₀ value of 2 μg/mL for MRSA. Ceftobiprole also inhibits gram-positive and gram-negative pathogens .

HY-103251

PF-5081090 LpxC-4	Antibiotic Bacterial	Infection
PF-5081090 (LpxC-4) is a potent LpxC inhibitor, is a rapidly bactericidal with broad-spectrum activity. PF-5081090 serves as a regulator of lipid A biosynthesis in Gram-negative pathogens .

HY-106574

Ceftobiprole medocaril BAL5788	Bacterial	Infection Inflammation/Immunology
Ceftobiprole medocaril (BAL5788) is the parenteral proagent of Ceftobiprole (HY-112579). Ceftobiprole is a parenteral pyrrolidinone cephalosporin. Ceftobiprole is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci. Ceftobiprole also inhibits gram-positive and gram-negative pathogens .

HY-106574A

Ceftobiprole medocaril sodium BAL5788 sodium	Bacterial	Infection Inflammation/Immunology
Ceftobiprole medocaril (BAL5788) sodium is the parenteral proagent of Ceftobiprole (HY-112579). Ceftobiprole is a parenteral pyrrolidinone cephalosporin. Ceftobiprole is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci. Ceftobiprole also inhibits gram-positive and gram-negative pathogens .

HY-106991A

Amustaline dihydrochloride S-303 dihydrochloride	HIV Bacterial	Infection
Amustaline (S-303) dihydrochloride, a nucleic acid-targeted alkylator, is an efficient pathogen inactivation agent for blood components containing red blood cells. Amustaline dihydrochloride has three components: an acridine anchor (an intercalator that targets nucleic acids non-covalently), an effector (a bis-alkylator group that reacts with nucleophiles), and a linker (a small flexible carbon chain containing a labile ester bond that hydrolyzes at neutral pH to yield non-reactive breakdown products) .

HY-P2260

Tat-beclin 1 1 Publications Verification	Autophagy HIV	Infection
Tat-beclin 1, a peptide derived from a region of the autophagy protein (beclin 1), is a potent inducer of autophagy and interacts with negative regulator of autophagy, GAPR-1 (GLIPR2). Tat-beclin 1 decreases the accumulation of polyglutamine expansion protein aggregates and the replication of several pathogens (including HIV-1) in vitro, and reduces mortality in mice infected with chikungunya (CHIKV) or West Nile virus (WNV) .

HY-P2260A

Tat-beclin 1 TFA	Autophagy HIV	Infection
Tat-beclin 1 TFA, a peptide derived from a region of the autophagy protein (beclin 1), is a potent inducer of autophagy and interacts with negative regulator of autophagy, GAPR-1 (GLIPR2). Tat-beclin 1 TFA decreases the accumulation of polyglutamine expansion protein aggregates and the replication of several pathogens (including HIV-1) in vitro, and reduces mortality in mice infected with chikungunya (CHIKV) or West Nile virus (WNV) .

HY-B2026S

Propamocarb-d7	Fungal	Infection
Propamocarb-d₇ is the deuterium labeled Propamocarb[1]. Propamocarb is a systemic fungicide. Propamocarb is widely used to protect cucumbers, tomatoes and other plants from pathogens[2].

HY-B0925AS

Oxacillin-d5	Bacterial Antibiotic	Infection
Oxacillin-d₅ is the deuterium labeled Oxacillin[1]. Oxacillin is an orally active synthetic penicillin with good bactericidal activity against staphylococci and other gram-positive pathogens[2].

HY-U00380

Tigemonam

Bacterial Antibiotic Infection

Tigemonam is a monobactam, with potent activity against Gram-negative aerobic bacterial pathogens.
HY-A0277

Cyproconazole

Bacterial Others

Cyproconazole is a triazole fungicide that is used agriculturally for protection of crops against a wide variety of fungal pathogens.

Tigemonam	Bacterial Antibiotic	Infection
Tigemonam is a monobactam, with potent activity against Gram-negative aerobic bacterial pathogens.

Cyproconazole	Bacterial	Others
Cyproconazole is a triazole fungicide that is used agriculturally for protection of crops against a wide variety of fungal pathogens.

HY-14855B

Tedizolid phosphate 10+ Cited Publications TR-701FA	Bacterial Antibiotic	Infection
Tedizolid phosphate (TR-701FA) is a novel oxazolidinone with activity against Gram-positive pathogens.

HY-B1897A

Menadione bisulfite sodium Menadione sodium bisulfite; Vitamin K3 sodium bisulfite	Others	Others
Menadione bisulfite (sodium) is used as an agent to induce acute oxidative stress, and to function as a plant-defense activator against several pathogens.

HY-B2026

Propamocarb

Propamocarb is a systemic fungicide. Propamocarb is widely used to protect cucumbers, tomatoes and other plants from pathogens .
HY-142912

Stemphyperylenol

Fungal Others

Stemphyperylenol displays a potent antifungal activity against the plant pathogen Alternaria solani with MIC of 1.57 μM.
HY-B0925A

Oxacillin

Oxacillin is an orally active synthetic penicillin with good bactericidal activity against staphylococci and other gram-positive pathogens .

HY-107004A

Amotosalen hydrochloride 1 Publications Verification S-59	Others	Inflammation/Immunology
Amotosalen hydrochloride (S-59) is a light-activated, DNA-, RNA-crosslinking psoralen compound, which is used to neutralise pathogens .

Cat. No.	Product Name

HY-L007

Immunology/Inflammation Compound Library

5006 compounds

The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease. To function properly, an immune system must detect a wide variety of agents, known as pathogens, from viruses to parasitic worms, and distinguish them from the organism's own healthy tissue. Inflammation is also the body's attempt at self-protection to remove harmful stimuli and begin the healing process. It’s part of the body's immune response. The immune system recognizes damaged cells, irritants, and pathogens, and inflammation begins the healing process. Inflammatory abnormalities are a large group of disorders that underlie a vast variety of human diseases. The immune system is often involved with inflammatory disorders, demonstrated in both allergic reactions and some myopathies, with many immune system disorders resulting in abnormal inflammation.

MCE designs a unique collection of 5006 compounds that are useful tool for Immunology/Inflammation research or autoimmune inflammatory diseases drug discovery.

HY-L175

Inflammasomes related Compound Library

67 compounds

Inflammasomes are classic pattern recognition receptors for natural immune responses. Inflammasomes are polymeric protein complexes that regulate inflammatory responses and pyrolytic cell death, thereby exerting the host's defense against microorganisms. Inflammasomes sensors are associated with adapter proteins, activating inflammatory caspase-1, releasing inflammatory cytokines and inducing cell death, endowing the host with defense against pathogens. NLRP1, NLRP3, NLRC4, AIM2, and pyrin are considered typical inflammasomes because they convert cysteine asparaginase-1 into catalytically active capsaicin-1. In addition to infectious diseases, the importance of inflammasomes is also related to various clinical diseases, such as autoimmune diseases, neurodegeneration and metabolic disorders, and the development of cancer. Therefore, it is necessary to strictly regulate the activation and function of inflammasomes to avoid accidental host tissue damage while inducing pathogens to kill the inflammatory response.

MCE designs a unique collection of 67 inflammasomes related compounds. It is a good tool to be used for research on Inflammation, cancer and other diseases.

HY-L059

Pyroptosis Compound Library

1256 compounds

Programmed cell death pathways, including apoptosis, pyroptosis and necroptosis, are regulated by unique sets of host proteins that coordinate a variety of biological outcomes. Pyroptosis is a highly inflammatory form of programmed cell death that occurs most frequently upon infection with intracellular pathogens and is likely to form part of the antimicrobial response. This process promotes the rapid clearance of various bacterial, viral, fungal and protozoan infections by removing intracellular replication niches and enhancing the host's defensive responses. Pyroptosis has been widely studied in inflammatory and infection disease models. Recently, there are growing evidences that pyroptosis also plays an important role in the development of cancer, cardiovascular diseases and Metabolic disorder, etc.

MCE designs a unique collection of 1256 pyroptosis-related compounds mainly focusing on the key targets in the pyroptosis signaling pathway and can be used in the research of pyroptosis signal pathway and related diseases.

HY-L174

Macrophage Related Compound Library

153 compounds

Macrophages are effector cells of the innate immune system, engulfing bacteria and secreting pro-inflammatory and antibacterial mediators. They are an important component of the first line defense against pathogens and tumor cells. In addition, macrophages play an important role in eliminating damaged cells through programmed cell death. Like all immune cells, macrophages originate from pluripotent hematopoietic stem cells in the bone marrow. Macrophages play key functions in many physiological processes beyond homeostasis and innate immunity, including metabolic function, cell debris clearance, tissue repair, and remodeling. In order to fulfill their different functional roles, macrophages can polarize into a series of phenotypes, including classic (pro inflammatory, M1) and alternative (anti-inflammatory, healing promoting, M2) activation states, as well as a wide range of regulatory phenotypes and subtypes. Macrophages exist in all vertebrate tissues and have a dual function in host protection and tissue damage, maintaining a good balance.

MCE designs a unique collection of 153 macrophage related compounds. It is a good tool to be used for research on Inflammation, cancer and other diseases.

Cat. No.	Product Name	Type

HY-W011426

Isopropyl palmitate

Propan-2-yl hexadecanoate

Drug Delivery

Isopropyl palmitate is an fatty acid ester. Isopropyl palmitate can be used for design and characterization of bioactive bilayer films. The bilayer membrane not only has the ability to scavenge free radicals and inhibit lipid peroxidation, but also can inhibit the growth of known foodborne pathogens. Isopropyl palmitate can be used as an excipient, such as lubricant, oily carrier, solvent, controlled-release transdermal film. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-157353

MacConkey Agar MAC	Microbial Culture
MacConkey Agar (MAC) can be used for selective isolation and culture of intestinal pathogens. The composition of 1 liter of MacConkey Agar (MAC) is: 20.0g peptone, 10.0 g lactose, 1.5 g Bile salt number three, 5.0 g sodium chloride, 0.03g Neutral red, 0.001 g Crystal viol and 15.0 g agar .

HY-157364

Levine Eosin-Methylene Blue Agar Medium Levine EMB Agar	Microbial Culture
Levine Eosin-Methylene Blue Agar Medium (Levine EMB Agar) is a weakly selective medium for the isolation of intestinal pathogens, especially E. coli. The composition of 1 liter of Levine Eosin-Methylene Blue Agar Medium: 10.0 g Peptone, 10.0 g lactose, 2.0 g dipotassium hydrogen phosphate, 15.0 g agar, 0.4 g eosin, 0.065 g methylene blue .

HY-W749867

Ca(Ⅱ)-EDTA disodium dihydrate Calcium disodium EDTA dihydrate	Chelators
CaⅡ-EDTA disodium dihydrate (Calcium disodium EDTA dihydrate) is an orally active metal chelating reagent, exhibits bactericidal activities against periodontal pathogens Aggregatibacter actinomycetemcomitans, Prevotella intermedia and Porphyromonas gingivalis . CaⅡ-EDTA disodium dihydrate is effective chelating antidotes for lead- and cadmium poisoning .

HY-P3021

Human milk lysozyme	Biochemical Assay Reagents
Human milk lysozyme is the lysozyme found in human milk. Human milk lysozyme is thought to be a key defense factor in protecting the gastrointestinal tract of newborns against bacterial infection .

Cat. No.	Product Name	Target	Research Area

HY-P2260

Tat-beclin 1 1 Publications Verification	Autophagy HIV	Infection
Tat-beclin 1, a peptide derived from a region of the autophagy protein (beclin 1), is a potent inducer of autophagy and interacts with negative regulator of autophagy, GAPR-1 (GLIPR2). Tat-beclin 1 decreases the accumulation of polyglutamine expansion protein aggregates and the replication of several pathogens (including HIV-1) in vitro, and reduces mortality in mice infected with chikungunya (CHIKV) or West Nile virus (WNV) .

HY-P3350

LS-BF1	Bacterial	Infection
LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].

HY-P2260A

Tat-beclin 1 TFA	Autophagy HIV	Infection
Tat-beclin 1 TFA, a peptide derived from a region of the autophagy protein (beclin 1), is a potent inducer of autophagy and interacts with negative regulator of autophagy, GAPR-1 (GLIPR2). Tat-beclin 1 TFA decreases the accumulation of polyglutamine expansion protein aggregates and the replication of several pathogens (including HIV-1) in vitro, and reduces mortality in mice infected with chikungunya (CHIKV) or West Nile virus (WNV) .

HY-P2318

Bac2A TFA

Fungal

Bac2A TFA is an antimicrobial and immunomodulatory peptide. Bac2A TFA is a linear variant of bactenecin and is very effective against fungal pathogens.

HY-P4327

Hispidalin	Bacterial	Infection
Hispidalin is a novel antimicrobial peptide with broad and efficient antibacterial activity against various bacterial and fungal pathogens, and can be used as an antibacterial agent and food preservative .

HY-P10027

Clovibactin	Antibiotic Bacterial	Infection
Clovibactin is an antibiotic for drug-resistant bacterial pathogens without detectable resistance. Clovibactin TFA inihibits cell wall synthesis by targeting pyrophosphate of peptidoglycan precursors .

HY-P5740

Cacaoidin	Bacterial	Infection
Cacaoidin is a glycosylated lantibiotic isolated from a Streptomyces cacaoi strain. Cacaoidin has potent antibacterial activity against Gram-positive pathogens including Clostridium difficile .

HY-P5710

LCI peptide	Bacterial	Infection
LCI peptide is an antimicrobial peptide with antibacterial activity. LCI peptide is active against plant pathogens, Xanthomonas and Pseudomonas, including E. coli, Gentamicin-resistant MRSA and Xoo .

HY-P2291

Beta-defensin 103 isoform X1, pig	Bacterial	Inflammation/Immunology
Beta-defensin 103 isoform X1, pig is an antimicrobial peptide found in different living organisms, involved in the first line of defense in their innate immune response against pathogens .

HY-P2291A

Beta-defensin 103 isoform X1, pig TFA	Bacterial	Inflammation/Immunology
Beta-defensin 103 isoform X1, pig TFA is an antimicrobial peptide found in different living organisms, involved in the first line of defense in their innate immune response against pathogens .

HY-P10027A

Clovibactin TFA	Antibiotic Bacterial	Infection
Clovibactin TFA is the TFA salt form of Clovibactin (HY-P10027). Clovibactin TFA is an antibiotic for drug-resistant bacterial pathogens without detectable resistance. Clovibactin TFA inihibits cell wall synthesis by targeting pyrophosphate of peptidoglycan precursors .

HY-P2076

Dusquetide SGX942	p62 Bacterial	Infection Cancer
Dusquetide (SGX942) is a first-in-class innate defense regulator (IDR). Dusquetide modulates the innate immune response to both PAMPs and DAMPs by binding to p62. Dusquetide shows activity in both reducing inflammation and increasing clearance of bacterial infection . DAMPs: damage-associated molecular patterns; PAMPs: pathogen-associated molecular patterns

HY-P1884

LL-37, acetylated,amidated	Bacterial	Infection
LL-37, acetylated, amidated is a cathelicidin peptide LL-37 acetylated on the N-terminus and amidated on the C-terminus. The single human cathelicidin peptide LL-37 has antimicrobial and anti-biofilm activity against multiple Gram-positive and Gram-negative human pathogens, and has wound-healing effects on the host .

HY-P2076A

Dusquetide TFA SGX942 TFA	p62 Bacterial	Infection Cancer
Dusquetide (SGX942) TFA is a first-in-class innate defense regulator (IDR). Dusquetide TFA modulates the innate immune response to both PAMPs and DAMPs by binding to p62. Dusquetide TFA shows activity in both reducing inflammation and increasing clearance of bacterial infection . DAMPs: damage-associated molecular patterns; PAMPs: pathogen-associated molecular patterns

HY-P5706

HG2	Bacterial	Infection Inflammation/Immunology
HG2 is a fast-acting antimicrobial peptide. HG2 shows anti-biofilm and anti-inflammatory activities. HG2 is active against Gram-positive pathogens, especially against MRSA strains (MIC: 16-32?μg/mL). HG2 can bind to bacterial lipids and reduces ATP concentration in S. aureus MRSA USA300 cells .

HY-P5709

HG4	Bacterial	Infection Inflammation/Immunology
HG4 is a fast-acting antimicrobial peptide. HG4 shows anti-biofilm and anti-inflammatory activities. HG4 is active against Gram-positive pathogens, especially against MRSA strains (MIC: 32-64?μg/mL). HG4 can bind to bacterial lipids and reduces ATP concentration in S. aureus MRSA USA300 cells .

HY-P5693

HBA(111–142)	Bacterial CMV HSV	Infection
HBA(111-142), an antimicrobial peptide, is a C-terminal 32-mer fragment of alpha-hemoglobin. HBA(111-142) has antibacterial activity against the ESKAPE panel of pathogens. HBA(111-142) forms amyloid fibrils, and has antiviral activities. HBA(111-142) inhibits measles and herpes viruses (HSV-1, HSV-2, HCMV) .

HY-P5484

SMAP-18	Bacterial	Others
SMAP-18 is a biological active peptide. (SMAP-18 is a 18-amino acid residue peptide amide which is a truncated form of SMAP-29. Sheep myeloid antimicrobial peptide-29 (SMAP-29) displays extremely high antimicrobial activity against Pseudomonas strains, other Gram-negative bacteria, and multidrug-resistant pathogens. SMAP-18 displays much higher cell selectivity as compared to parental SMAP-29 because of its decreased hemolytic activity and retained antimicrobial activity.)

HY-P5601

Thanatin	Bacterial Fungal	Infection
Thanatin is an inducible cationic antimicrobial peptide. Thanatin is a pathogen-inducible single-disulfide-bond-containing β-hairpin AMP. Thanatin displays broad-spectrum activity against both Gram-negative and Gram-positive bacteria as well as against various species of fungi with MICs of 0.3-40 µM, 0.6-40 µM and 0.6-20 µM, respectively. Thanatin has the property of competitive replacement of divalent cations from bacterial outer membrane (OM), leading to OM disruption .

HY-P5601A

Thanatin TFA	Bacterial Fungal	Infection
Thanatin TFA is an inducible cationic antimicrobial peptide. Thanatin TFA s a pathogen-inducible single-disulfide-bond-containing β-hairpin AMP. Thanatin TFA displays broad-spectrum activity against both Gram-negative and Gram-positive bacteria as well as against various species of fungi with MICs of 0.3-40 µM, 0.6-40 µM and 0.6-20 µM, respectively. Thanatin TFA has the property of competitive replacement of divalent cations from bacterial outer membrane (OM), leading to OM disruption .

HY-P2260B

Tat-beclin 1 scrambled	HIV	Infection
Tat-beclin 1 scrambled is the scrambled part and a scrambled control of Tat-beclin 1 (HY-P2260), which is derived from a region of the autophagy protein, beclin 1. beclin 1 induces autophagy via binding human immunodeficiency virus, HIV-1 Nef and interacting with negative regulator GAPR-1 (GLIPR2). Tat-beclin 1 decreases the accumulation of polyglutamine expansion protein aggregates and the replication of several pathogens, such as HIV-1. Tat-beclin 1 also reduces mortality in mice infected with chikungunya or West Nile virus .

HY-P2260C

Tat-beclin 1 scrambled TFA	HIV	Infection
Tat-beclin 1 scrambled TFA is the scrambled part and a scrambled control of Tat-beclin 1 (HY-P2260), which is derived from a region of the autophagy protein, beclin 1. beclin 1 induces autophagy via binding human immunodeficiency virus, HIV-1 Nef and interacting with negative regulator GAPR-1 (GLIPR2). Tat-beclin 1 decreases the accumulation of polyglutamine expansion protein aggregates and the replication of several pathogens, such as HIV-1. Tat-beclin 1 also reduces mortality in mice infected with chikungunya or West Nile virus .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W009886

3,4,5-Trimethoxybenzaldehyde	Infection Clerodendrum trichotomum Thunb. Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Verbenaceae Source classification Plants Disease Research Fields	Bacterial
3,4,5-Trimethoxybenzaldehyde is an intermediate for the synthesis of various pharmaceuticals, especially for trimethoprim used to research bacterial infections, including urinary tract pathogens infection.

HY-N5124

Meloside A 1 Publications Verification Isovitexin 2''-O-glucoside; Isovitexin 2''-O-β-D-glucoside	Infection Flavonoids Classification of Application Fields Flavones Source classification Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H.F.Chow. Phenols Polyphenols Plants Rhamnaceae Disease Research Fields	Others
Meloside A (Isovitexin 2''-O-glucoside) is a phenylpropanoid isolated from barley with antioxidant activity. In barley, phenylpropanoids have been described as having protective properties against excess UV-B radiation and have been linked to resistance to pathogens .

HY-126869

Pseudomonic acid D	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Bacterial Parasite
Pseudomonic acid D is a microbial inhibitor. Pseudomonic acid D potently inhibits mycoplasmas and bacterial pathogens. Pseudomonic acid D can be produced by fermentation with Pseudomonas fluorescens .

HY-N10584

Malacidin A	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields	Antibiotic Bacterial
Malacidin A is the calcium-dependent antibiotic (CDAs). Malacidin A is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria .

HY-126604

Pyranonigrin A	Infection Alkaloids Human Gut Microbiota Metabolites Microorganisms Pyrrole Alkaloids Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Others
Pyranonigrin A is isolated and identified from Penicillium brocae MA-231. Pyranonigrin A shows potent activity against a broad spectrum of human-, aqua-, and plant-pathogens .

HY-N12262

(+)-Epieudesmin	Structural Classification other families Hernandia nymphaeifolia (C. Presl) Kubitzki Source classification Lignans Phenylpropanoids Plants	Bacterial
(+)-Epieudesmin is an antineoplastic agent. (+)-Epieudesmin has marginal cancer cell line inhibitory activities. (+)-Epieudesmin inhibits the growth of Gram-negative pathogen .

HY-W018025

5,6-Dihydroxyindole	Natural Products Classification of Application Fields Source classification Phenols Polyphenols Endogenous metabolite Disease Research Fields Inflammation/Immunology	Bacterial Fungal Parasite Endogenous Metabolite
5,6-Dihydroxyindole, a melanin precursor, has a broad-spectrum antibacterial, antifungal, antiviral, antiparasitic activity. 5,6-Dihydroxyindole has cytotoxic effects and is strongly toxic against various pathogens .

HY-N7001

Dehydrotomatine	Infection Alkaloids Piperidine Alkaloids Structural Classification Classification of Application Fields Source classification Lycopersicon esculentum Miller Plants Solanaceae Disease Research Fields	Bacterial Fungal
Dehydrotomatine is a steroidal glycoalkaloid (SGA). α-tomatine and Dehydrotomatine accumulate in the mature green fruits, leaves, and flowers of tomatoes (Solanum lycopersicum) and function as defensive compounds against pathogens and predators. SGAs show toxic effects on fungi, bacteria, insects, and animals .

HY-A0279

Pristinamycin Pristinamycine	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields	Bacterial Antibiotic
Pristinamycin, produced by Streptomyces pristinaespiralis, is an orally active streptogramin-like antibiotic consisting of two chemically unrelated components: Pristinamycin I (PI) and Pristinamycin II (PII). Pristinamycin is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant S. aureus (VRSA) and Enterococcus faecium (VREF) .

HY-118149A

(±)9-HpODE	Infection other families Classification of Application Fields Animals Ketones, Aldehydes, Acids Source classification Plants Disease Research Fields	Bacterial Fungal Parasite
(±)9-HpODE is a long chain lipid hydroperoxide, is a product of linoleic acid peroxidation. (±)9-HpODE can induce oxidation of intracellular glutathione (GSH). (±)9-HpODE also exhibits antimicrobial activity against various fungal and bacterial pathogens .

HY-N10572

Antibacterial synergist 2	Structural Classification Microorganisms Antibiotics Antibacterial Disease Research	Bacterial
Antibacterial synergist 2 (compound 27) is a biofilm inhibitor. Antibacterial synergist 2 shows inhibitory effects to S. enterica, S. aureus, P. aeruginosa and C. albicans. Antibacterial synergist 2 can be used for the research related to biofilm-forming pathogens .

HY-N7378

N-Hydroxypipecolic acid 2 Publications Verification 1-Hydroxy-2-piperidinecarboxylic acid; NHP	Structural Classification other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Inflammation/Immunology Disease Research Fields	Bacterial
N-Hydroxypipecolic acid (1-Hydroxy-2-piperidinecarboxylic acid), a plant metabolite and a systemic acquired resistance (SAR) regulator, orchestrates SAR establishment in concert with the immune signal salicylic acid. N-Hydroxypipecolic acid accumulates systemically in the plant foliage in response to pathogen attack. N-Hydroxypipecolic acid induces SAR to bacterial and oomycete infection .

HY-N7378A

N-Hydroxypipecolic acid potassium 1-Hydroxy-2-piperidinecarboxylic acid potassium; NHP potassium	Structural Classification other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Inflammation/Immunology Disease Research Fields	Bacterial
N-Hydroxypipecolic acid potassium (1-Hydroxy-2-piperidinecarboxylic acid potassium), a plant metabolite and a systemic acquired resistance (SAR) regulator, orchestrates SAR establishment in concert with the immune signal salicylic acid. N-Hydroxypipecolic acid potassium accumulates systemically in the plant foliage in response to pathogen attack. N-Hydroxypipecolic acid potassium induces SAR to bacterial and oomycete infection .

HY-N6051

(-)-Maackiain	Infection Monophenols Classification of Application Fields Leguminosae Terpenoids Source classification Phenols Diterpenoids Plants Sophora flavescens Aiton Disease Research Fields	Fungal
(-)-Maackiain is a pterocarpan phytoalexin produced from Sophora flavescens. (-)-Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts .

HY-N0610

trans-Cinnamic acid trans-3-Phenylacrylic acid	Structural Classification Cinnamomum cassia (L.) D. Don Microorganisms Classification of Application Fields Simple Phenylpropanols Source classification Phenylpropanoids Plants Lauraceae Endogenous metabolite Disease Research Fields Cancer	Bacterial Endogenous Metabolite
trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1 .

HY-B0221

Amphotericin B Maximum Cited Publications 13 Publications Verification	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Fungal Antibiotic Bacterial Parasite
Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.

HY-N10207

Penicitide A	Infection Natural Products Microorganisms Classification of Application Fields Source classification Marine natural products Disease Research Fields Marine microorganism	Endogenous Metabolite
Penicitide A is a marine secondary metabolite. Penicitide A shows moderate cytotoxicity against pathogen A. brassicae and the human hepatocellular liver carcinoma (HepG2) cell line .

HY-B1920

Josamycin EN-141	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields	Bacterial Antibiotic
Josamycin (EN-141) is a macrolide antibiotic exhibiting antimicrobial activity against a wide spectrum of pathogens, such as bacteria. The dissociation constant K_d from ribosome for Josamycin is 5.5 nM.

HY-N0363

(+)-Columbianetin (S)-Columbianetin	Structural Classification Classification of Application Fields Source classification Coumarins Phenylpropanoids Plants Umbelliferae Seriphidium transiliense Inflammation/Immunology Disease Research Fields	Fungal
(+)-Columbianetin is an isomer of Columbianetin. Columbianetin is a phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage. Columbianetin exhibits excellent anti-fungal and anti-inflammatory activity .

HY-N0363A

(+)-Columbianetin acetate (S)-Columbianetin acetate	Structural Classification other families Classification of Application Fields Source classification Coumarins Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields	Fungal
(S)-Columbianetin acetate is an isomer of Columbianetin. Columbianetin is a phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage. Columbianetin exhibits excellent anti-fungal and anti-inflammatory activity .

HY-W087988

3-Pentanol	Infection Natural Products Classification of Application Fields Animals Source classification Disease Research Fields	Bacterial
3-Pentanol is an active organic compound produced by plants and is a component of emitted insect sex pheromones. 3-pentanol elicits plant immunity against microbial pathogens and an insect pest in crop plants .

HY-N10280

Asperglaucin A	Infection Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Disease Research Fields	Bacterial Endogenous Metabolite
Asperglaucin A represents an unusual phthalide-like derivative. Asperglaucin A exhibits potent antibacterial activities against two plant pathogens Pseudomonas syringae pv actinidae (Psa) and Bacillus cereus, with an MIC value of 6.25 μM .

HY-N8853

Victoxinine

Structural Classification Natural Products Microorganisms Source classification

Others

Victoxinine is a metabolite of Bipolaris sp. Victoxinine has minor phytotoxic .

HY-B0221R

Amphotericin B (Standard)	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Fungal Antibiotic Bacterial Parasite
Amphotericin B (Standard) is the analytical standard of Amphotericin B. This product is intended for research and analytical applications. Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.

HY-N2472

Medicagenic acid Castanogenin	Infection Triterpenes Structural Classification Classification of Application Fields Herniaria glabra Linnaeus. Terpenoids Plants Disease Research Fields Caryophyllaceae	Bacterial
Medicagenic acid (Castanogenin) is isolated from the roots of Herniaria glabra, exhibits potent fungistatic effects against several plant pathogens and human dermatophytes . Medicagenic acid (Castanogenin) has low enzyme inhibitory activities, the target enzymes are xanthine oxidase, collagenase, elastase, tyrosinase, ChE .

HY-N2805

9-Oxonerolidol	Structural Classification Natural Products Source classification Valeriana officinalis Linn. Plants Valerianaceae	Bacterial
9-Oxonerolidol is a farnesane-type sesquiterpenoid with anti-pathogens activity. 9-Oxonerolidol can be isolated from Chiliadenus lopadusanus. 9-Oxonerolidol acts as a post-infectional inhibitor from plants, and inhibits Gram+ and Gram? bacteria resistant to the antibiotic .

HY-N10281

Asperglaucin B	Infection Monophenols Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Disease Research Fields	Bacterial
Asperglaucin B is an alkylated salicylaldehyde derivative from the fungus Aspergillus chevalieri SQ-8, with antibacterial activities. Asperglaucin B displays potent antibacterial activities against two plant pathogens Pseudomonas syringae pv actinidae (Psa) and *Bacillus cereus*, with an MIC value of 6.25 μM .

HY-N7681

Taxifolin 7-O-β-D-glucoside Taxifolin 7-O-glucoside	Flavanonols Flavonoids Classification of Application Fields Cercis chinensis Bunge Source classification Other Diseases Phenols Polyphenols Plants Compositae Disease Research Fields	Others
Taxifolin 7-O-β-D-glucoside (Taxifolin 7-O-glucoside) is one of the main metabolites at the seed germination stage in Scutellaria baicalensis. Taxifolin 7-O-β-D-glucoside, a flavonoid, mainly exists in the episperm and participates in defending against pathogens and UV-damage .

HY-N6743

Cercosporin	Natural Products Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Disease Research Fields Cancer	PKC
Cercosporin is produced by a plant pathogen, Pseudocercosporella capsellae. Cercosporin is a potent photosensitizer with a short activation wavelength, mostly suitable for superficial photodynamic therapy (PDT) treatments, especially when it is necessary to avoid perforations . Cercosporin contains the perylenequinone structural features necessary to PKC activity with an IC₅₀ of 0.6-1.3 μM .

HY-122267

Clovamide trans-Clovamide	Alkaloids Structural Classification other families Other Alkaloids Source classification Phenols Polyphenols Plants	Reactive Oxygen Species Bacterial Influenza Virus Apoptosis
Clovamide (trans-Clovamide), a natural phenolic compound, is a potent antioxidant. Clovamide is an excellent ROS and oxygen radical scavenger. Clovamide also has anti-inflammatory and neuroprotective effects . Clovamide is an anti-microbial with activity against the human pathogens influenza A subtype H5N1, *Trypanosoma evansi, and Heliobacter pylori* .

HY-N9480

Vinaxanthone SM-345431	Structural Classification Microorganisms Xanthones Classification of Application Fields Source classification Phenols Disease Research Fields Cancer	Phospholipase Bacterial
Vinaxanthone (SM-345431) is a potent and selective semaphorin3A, phospholipase C (PLC) and FabI inhibitor, with IC₅₀s of 0.1-0.2 μM and 0.9 mM for semaphorin3A and FabI. Vinaxanthone inhibits the substrate (t-o-NAC thioester) and the cofactor (NADPH) with K_is of 3.1 μM and 1.0 μM, respectively. Vinaxanthone can be used to handle infections caused by multidrug-resistant pathogens .

HY-N0704

Agrimol B	Agrimonia pilosa Ledeb. Structural Classification Classification of Application Fields Rosaceae Phenols Polyphenols Metabolic Disease Plants Disease Research Fields	Sirtuin PPAR Fatty Acid Synthase (FASN) c-Myc Bacterial
Agrimol B, a polyphenol, is an orally active and potent SIRT1 activator. Agrimol B shows anti-adipogenic and anticancer activity. Agrimol B shows antibacterial activity against plant pathogens. Agrimol B dramatically inhibits 3T3-L1 adipocyte differentiation by reducing PPARγ, C/EBPα, FAS, UCP-1, and apoE expression. The action of Agrimol B on the cancer cells is likely derived from its effect on c-MYC, SKP2 and p27 .

HY-N12240

Oleanolic aldehyde	Triterpenes Structural Classification Terpenoids Source classification Vitis vinifera cv. Zalema Plants Vitaceae	Bacterial
Oleanolic aldehyde is an antimicrobial compound used to inhibit oral bacteria. Oleanolic aldehyde inhibits Streptococcus mutans and Porphyromonas gingivalis, which are associated with dental caries and periodontal disease, with minimum inhibitory concentrations (MICs) of 488 μg/mL and 250 μg/mL, respectively .

Cat. No.	Product Name	Chemical Structure

HY-B2026S

Propamocarb-d7
Propamocarb-d₇ is the deuterium labeled Propamocarb[1]. Propamocarb is a systemic fungicide. Propamocarb is widely used to protect cucumbers, tomatoes and other plants from pathogens[2].

HY-B0272S2

Rifampicin-d4
Rifampicin-d₄ is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities.

HY-W020005

2-Carboxyphenol-d4

2-Carboxyphenol-d4 is the deuterium labeled 2-Carboxyphenol. 2-Carboxyphenol is a plant hormone and mediates host responses against microbial pathogens.

HY-B0925AS

Oxacillin-d5
Oxacillin-d₅ is the deuterium labeled Oxacillin[1]. Oxacillin is an orally active synthetic penicillin with good bactericidal activity against staphylococci and other gram-positive pathogens[2].

HY-B0272S

Rifampicin-d3
Rifampicin-d₃ is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities[1][2].

HY-B0272S1

Rifampicin-d8
Rifampicin-d8 (Rifampin-d8) is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities.

HY-N0610S

trans-Cinnamic acid-d5
trans-Cinnamic acid-d₅ is the deuterium labeled trans-Cinnamic acid[1]. trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1[2].

HY-N0610S1

trans-Cinnamic acid-d7
trans-Cinnamic acid-d₇ is the deuterium labeled trans-Cinnamic acid[1]. trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1[2].

HY-B0221S

Amphotericin B-13C6
Amphotericin B- ¹³C₆ is ¹³C labeled Amphotericin B (HY-B0221). Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.

HY-W009886S

3,4,5-Trimethoxybenzaldehyde-d3
3,4,5-Trimethoxybenzaldehyde-d3 is the deuterium labeled 3,4,5-Trimethoxybenzaldehyde. 3,4,5-Trimethoxybenzaldehyde is an intermediate for the synthesis of various pharmaceuticals, especially for trimethoprim used to research bacterial infections, including urinary tract pathogens infection.

HY-B0843AS

Metalaxyl-M-d6
Metalaxyl-M-d6 is the deuterium labeled Metalaxyl-M[1]. Metalaxyl-M ((R)-Metalaxyl) is the active (R)-enantiomer of Metalaxyl. Metalaxyl-M is a broad-spectrum fungicide that inhibits protein and ribosomal RNA synthesis in fungi. Metalaxyl is used for research of plant diseases caused by pathogens of the Oomycota division[2].

HY-W087988S

3-Pentanol-d5
3-Pentanol-d₅ is the deuterium labeled 3-Pentanol[1]. 3-Pentanol is an active organic compound produced by plants and is a component of emitted insect sex pheromones. 3-pentanol elicits plant immunity against microbial pathogens and an insect pest in crop plants[2].

HY-B0272S3

Rifampicin-d11
Rifampicin-d₁₁ (Rifampin-d₁₁; Rifamycin AMP-d₁₁)is the deuterium labeledRifampicin(HY-B0272) . Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities. Rifampicin shows anti-orthopoxvirus activity .

HY-15660S

Efinaconazole-d4
Efinaconazole-d₄ is the deuterium labeled Efinaconazole. Efinaconazole (KP-103) is a triazole antifungal agent and againsts T. mentagrophytes SM-110 and C. albicans ATCC 10231 with MICs of 0.0039 μg/mL and 0.00098 μg/mL, respectively[1]. Efinaconazole has a potent in vitro activity against fungal pathogens including dermatophytes, Candida and Malassezia species[1].

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