1. Immunology/Inflammation
    NF-κB
    Metabolic Enzyme/Protease
    Anti-infection
    Apoptosis
  2. Reactive Oxygen Species
    Bacterial
    Influenza Virus
    Apoptosis
  3. Clovamide

Clovamide (Synonyms: trans-Clovamide)

Cat. No.: HY-122267
Handling Instructions

Clovamide (trans-Clovamide), a natural phenolic compound, is a potent antioxidant. Clovamide is an excellent ROS and oxygen radical scavenger. Clovamide also has anti-inflammatory and neuroprotective effects. Clovamide is an anti-microbial with activity against the human pathogens influenza A subtype H5N1, Trypanosoma evansi, and Heliobacter pylori.

For research use only. We do not sell to patients.

Clovamide Chemical Structure

Clovamide Chemical Structure

CAS No. : 53755-02-5

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Description

Clovamide (trans-Clovamide), a natural phenolic compound, is a potent antioxidant. Clovamide is an excellent ROS and oxygen radical scavenger. Clovamide also has anti-inflammatory and neuroprotective effects[1][2]. Clovamide is an anti-microbial with activity against the human pathogens influenza A subtype H5N1, Trypanosoma evansi, and Heliobacter pylori[3].

In Vitro

Clovamide is able to protect neurons from injury in three in vitro models of neuronal death: oxidative stress, excitotoxicity and OGD/reoxygenation. In SH-SY5Y human neuroblastoma cells, Clovamide (10-100 µM) significantly protects cell death, with an EC50 value of 3.6 µM. Clovamide also significantly enhances PPARγ expression[2].
Clovamide inhibits growth of three pathogens of cacao in the genus Phytophthora, is a substrate for cacao polyphenol oxidase, and is a contributor to enzymatic browning. Clovamide inhibiteds proteinase and pectinase in vitro[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

359.33

Formula

C₁₈H₁₇NO₇

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Clovamide
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