Desacetylcephapirin sodium
Based on 1 Customer Validation
Desacetylcephapirin (Deacetylcephapirin) sodium is an active metabolite of Cephapirin (HY-A0153A). Desacetylcephapirin sodium has antimicrobial against S. aureus and coagulase-negative staphylococci mastitis pathogen.
For research use only. We do not sell to patients.
- Purity : 97.0%
- CAS No.: 104557-24-6
- Formula: C15H14N3NaO5S2
- Molecular Weight:403.41
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
Antibacterial[2]
In Vitro
Desacetylcephapirin sodium exhibits inhibitory activity on Streptococcus dysgalactiae, with MIC50s both of 0.25 μg/mL for clinical and subclinical bacterial strain[2].
Desacetylcephapirin sodium exhibits inhibitory activity on coagulase-negative staphylococci mastitis pathogen, with MIC50s both of 0.12 μg/mL for clinical and subclinical bacterial strain[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 104557-24-6
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Appearance Solid
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Molecular Weight 403.41
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Formula C15H14N3NaO5S2
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Color Off-white to light yellow
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SMILES
O=C(C(N12)=C(CO)CS[C@]2([H])[C@H](NC(CSC3=CC=NC=C3)=O)C1=O)O[Na]
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Synonyms
Deacetylcephapirin sodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
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Data Sheet (269 KB)
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SDS (558 KB)
- English - EN (558 KB)
- Français - FR (558 KB)
- Deutsch - DE (558 KB)
- Norwegian - NO (558 KB)
- Español - ES (558 KB)
- Swedish - SV (558 KB)
- Italian - IT (558 KB)
- Korean - KR (558 KB)
- Portuguese - PT (558 KB)
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Handling Instructions (2659 KB)
References
[1]. B. E. Cabana, et al. Comparative Pharmacokinetics and Metabolism of Cephapirin in Laboratory Animals and Humans. Antimicrob Agents Chemother. 1976 Aug; 10(2): 307-317. [Content Brief]
[2]. Cristina S Cortinhas, et al. Minimum inhibitory concentrations of cephalosporin compounds and their active metabolites for selected mastitis pathogens. Am J Vet Res. 2013 May;74(5):683-90. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Desacetylcephapirin sodium Related Classifications
HY-131989 Related Classifications
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