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Cat. No.: HY-103095A

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Enmetazobactam iodide

(Synonyms: AAI101 iodide)

6 Cited Publications

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Based on 6 publication(s) in Google Scholar

Enmetazobactam (iodide) (AAI101 (iodide)) is an extended-spectrum β-lactamase inhibitor, against many resistant Gram-negative pathogens.

For research use only. We do not sell to patients.

CAS No.: 1379594-98-5
Formula: C₁₁H₁₅IN₄O₅S
Molecular Weight:442.23

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Enmetazobactam iodide Chemical Structure

CAS No.: 1379594-98-5

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Biological Activity

Description

Enmetazobactam (iodide) (AAI101 (iodide)) is an extended-spectrum β-lactamase inhibitor, against many resistant Gram-negative pathogens^[1]^[2].

All Antibiotic Isoforms :

Chemical Information

CAS No. 1379594-98-5
Molecular Weight 442.23
Formula C₁₁H₁₅IN₄O₅S
SMILES

OC([C@@H]1N2[C@](CC2=O)([H])S(=O)([C@@]1(C)C[N+]3=NN(C)C=C3)=O)=O.[I-]
Synonyms

AAI101 iodide
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (6)

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Int J Antimicrob Agents

Activity of aztreonam in combination with novel β-lactamase inhibitors against metallo-β-lactamase-producing Enterobacterales from Spain. [Abstract]

2023 Apr;61(4):106738. PMID: 36736925
ACS Infect Dis

Assessing the Potency of β-Lactamase Inhibitors with Diverse Inactivation Mechanisms against the PenA1 Carbapenemase from Burkholderia multivorans. [Abstract]

2021 Apr 9;7(4):826-837. PMID: 33723985
Antimicrob Agents Chemother

Improved hydrolysis of piperacillin by OXA-48-like R214G variants, a selective advantage under piperacillin-tazobactam exposure. [Abstract]

2026 Jun 3;70(6):e0126725. PMID: 42053451
Antimicrob Agents Chemother

Relative inhibitory activities of newly developed diazabicyclooctanes, boronic acid derivatives, and penicillin-based sulfone β-lactamase inhibitors against broad-spectrum AmpC β-lactamases. [Abstract]

2024 Nov 6;68(11):e0077524. PMID: 39365068
Antimicrob Agents Chemother

Impact of Acquired Broad Spectrum β-Lactamases on Susceptibility to Novel Combinations Made of β-Lactams (Aztreonam, Cefepime, Meropenem, and Imipenem) and Novel β-Lactamase Inhibitors in Escherichia coli and Pseudomonas aeruginosa. [Abstract]

2023 Jul 18;67(7):e0033923. PMID: 37255469
Antimicrob Agents Chemother

Assessment of Activity and Resistance Mechanisms to Cefepime in Combination with the Novel β-Lactamase Inhibitors Zidebactam, Taniborbactam, and Enmetazobactam against a Multicenter Collection of Carbapenemase-Producing Enterobacterales. [Abstract]

2022 Feb 15;66(2):e0167621. PMID: 34807754

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Crandon JL, et al. In Vitro Activity of Cefepime/AAI101 and Comparators against Cefepime Non-susceptible Enterobacteriaceae. Pathogens. 2015 Aug 18;4(3):620-5. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Enmetazobactam iodide

6 Cited Publications

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Publications (6)
Purity & Documentation
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Enmetazobactam iodide

Publications Citing Use of MedChemExpress (MCE) Enmetazobactam iodide

All Antibiotic Isoforms

Biological Activity

Chemical Information

Publications (6)

Purity & Documentation

References

Calculators

Help & FAQs

Enmetazobactam iodide Related Classifications

HY-103095A Related Classifications