Human milk lysozyme
Based on 2 publication(s) in Google Scholar
Human milk lysozyme is the lysozyme found in human milk. Human milk lysozyme is thought to be a key defense factor in protecting the gastrointestinal tract of newborns against bacterial infection.
For research use only. We do not sell to patients.
- CAS No.: 12671-19-1
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Human milk lysozyme
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Biological Activity
Description
In Vitro
Human milk lysozyme (0-300 μg/mL; 2 h) shows superior activity against the skin pathogens Pr. acnes and C. minutissimum. Human milk lysozyme is devoid of activity against the Gram-negative E. coli, Salm. typhimurium, and Bord. bronchiseptica but exerts weak activity against Kleb. pneumonieae and Ps. aeruginosa. Human milk lysozyme shows no activity against Staph. epidermidis and weak activity against Staph. aureus and Str. zooepidemicus[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
EC Number
3.2.1.17
Specific Activity
≥ 100000 U/mg protein
Unit Definition
One unit is defined as the amount of enzyme that will produce a ΔA450 of 0.001 per min at pH 6.24 at 25°C, using a suspension of Micrococcus lysodeikticus as substrate, in a 2.6 mL reaction mixture (1 cm light path).
Chemical Information
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CAS No. 12671-19-1
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Appearance Solid
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Color White to off-white
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SMILES
[Human milk lysozyme]
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Sequence
Lys-Val-Phe-Glu-Arg-Cys-Glu-Leu-Ala-Arg-Thr-Leu-Lys-Arg-Leu-Gly-Met-Asp-Gly-Tyr-Arg-Gly-Ile-Ser-Leu-Ala-Asn-Trp-Met-Cys-Leu-Ala-Lys-Trp-Glu-Ser-Gly-Tyr-Asn-Thr-Arg-Ala-Thr-Asn-Tyr-Asn-Ala-Gly-Asp-Arg-Ser-Thr-Asp-Tyr-Gly-Ile-Phe-Gln-Ile-Asn-Ser-Arg-Tyr-Trp-Cys-Asn-Asp-Gly-Lys-Thr-Pro-Gly-Ala-Val-Asn-Ala-Cys-His-Leu-Ser-Cys-Ser-Ala-Leu-Leu-Gln-Asp-Asn-Ile-Ala-Asp-Ala-Val-Ala-Cys-Ala-Lys-Arg-Val-Val-Arg-Asp-Pro-Gln-Gly-Ile-Arg-Ala-Trp-Val-Ala-Trp-Arg-Asn-Arg-Cys-Gln-Asn-Arg-Asp-Val-Arg-Gln-Tyr-Val-Gln-Gly-Cys-Gly-Val
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Sequence Shortening
KVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTRATNYNAGDRSTDYGIFQINSRYWCNDGKTPGAVNACHLSCSALLQDNIADAVACAKRVVRDPQGIRAWVAWRNRCQNRDVRQYVQGCGV
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Shipping
Shipping with dry ice.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Int J Nanomedicine
Amine-Functionalized NiCoFe2O4 Nanoparticle-Embedded Sodium Alginate/Polyvinyl Alcohol Hydrogel Beads as a ROS-Generating, pH-Responsive Drug Carrier. [Abstract]2025 Dec 30:20:15939-15949. PMID: 41488861 -
Probiotics Antimicrob Proteins
2026 Mar 17. PMID: 41843357
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Human milk lysozyme Related Classifications
HY-P3021 Related Classifications
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