1. Anti-infection
    Neuronal Signaling
    Immunology/Inflammation
    GPCR/G Protein
  2. Bacterial
    Antibiotic
    Histamine Receptor
  3. Methicillin

Methicillin 

Cat. No.: HY-121544
Handling Instructions

Methicillin is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins.Methicillin can be used for the research of skin infections, osteomyelitis, and endocarditis.

For research use only. We do not sell to patients.

Methicillin Chemical Structure

Methicillin Chemical Structure

CAS No. : 61-32-5

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Description

Methicillin is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins.Methicillin can be used for the research of skin infections, osteomyelitis, and endocarditis[1].

IC50 & Target

β-lactam

 

In Vitro

Methicillin (20 μg/mL, 24 h) results in a rapid decrease in CFU of S. aureus[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Methicillin (Intramuscular administration, 40 mg/kg every 6 h, 5 days), in S. aureus.-infected rabbits[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

380.42

Formula

C17H20N2O6S

CAS No.
SMILES

OC([[email protected]@H]1N(C2=O)[[email protected]@](SC(C)1C)([H])[[email protected]@H]2NC(C(C(OC)=CC=C3)=C3OC)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Methicillin
Cat. No.:
HY-121544
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