Methenamine hippurate (Synonyms: Hexamine hippurate)

Cat. No.: HY-B1691 Purity: 99.55%: FAQs
Data Sheet SDS COA Handling Instructions

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Methenamine hippurate (Hexamine hippurate) is an orally active urinary antiseptic agent with a wide antibacterial spectrum. Methenamine hippurate is effective against most common urinary tract pathogens.

For research use only. We do not sell to patients.

Methenamine hippurate Chemical Structure

CAS No. : 5714-73-8

Size	Price	Stock	Quantity
Solid + Solvent
10 mM * 1 mL in DMSO ready for reconstitution	USD 60	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 60	In-stock	Estimated Time of Arrival: December 31
Solid
100 mg	USD 55	In-stock	Estimated Time of Arrival: December 31
250 mg	USD 110	In-stock	Estimated Time of Arrival: December 31
500 mg		Get quote
1 g		Get quote

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Purity & Documentation
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Description

In Vitro

Methenamine hippurate is a urinary antibacterial agent which releases formaldehyde and is excreted in the urine. Methenamine hippurate has a demonstrable activity in vitro at pH 5 to 6 against Escherichia coli, Staphylococcus aureus, Aerobacter aeroaenes, Pseudomonas aeruginosa and Proteus vulgaris, and a wide range of action against Klebsiella pneumoniae, Ps. aeruginosa, E. coli, Staph. aureus and Streptococcus haemolytic at pH of 7.4. This action is more effective than that of Methenamine alone, of Hippuric acid alone or of Sulphadiazine^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

319.36

Formula

C₁₅H₂₁N₅O₃

CAS No.

5714-73-8

Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CNC(C1=CC=CC=C1)=O.N2(C3)CN4CN3CN(C4)C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (313.13 mM; Need ultrasonic)

DMSO : 25 mg/mL (78.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.1313 mL	15.6563 mL	31.3126 mL
5 mM	0.6263 mL	3.1313 mL	6.2625 mL
10 mM	0.3131 mL	1.5656 mL	3.1313 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 100 mg/mL (313.13 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.55%

Select Batch:

Data Sheet (276 KB) SDS (252 KB)

COA (254 KB) HNMR (239 KB) LCMS (132 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O	1 mM	3.1313 mL	15.6563 mL	31.3126 mL	78.2816 mL
	5 mM	0.6263 mL	3.1313 mL	6.2625 mL	15.6563 mL
	10 mM	0.3131 mL	1.5656 mL	3.1313 mL	7.8282 mL
	15 mM	0.2088 mL	1.0438 mL	2.0875 mL	5.2188 mL
	20 mM	0.1566 mL	0.7828 mL	1.5656 mL	3.9141 mL
	25 mM	0.1253 mL	0.6263 mL	1.2525 mL	3.1313 mL
	30 mM	0.1044 mL	0.5219 mL	1.0438 mL	2.6094 mL
	40 mM	0.0783 mL	0.3914 mL	0.7828 mL	1.9570 mL
	50 mM	0.0626 mL	0.3131 mL	0.6263 mL	1.5656 mL
	60 mM	0.0522 mL	0.2609 mL	0.5219 mL	1.3047 mL
H₂O	80 mM	0.0391 mL	0.1957 mL	0.3914 mL	0.9785 mL
H₂O	100 mM	0.0313 mL	0.1566 mL	0.3131 mL	0.7828 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Methenamine5714-73-8HexamineInhibitorinhibitorinhibit

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