1. Anti-infection
  2. Bacterial
  3. Methenamine hippurate

Methenamine hippurate (Synonyms: Hexamine hippurate)

Cat. No.: HY-B1691
Handling Instructions

Methenamine hippurate (Hexamine hippurate) is an orally active urinary antiseptic agent with a wide antibacterial spectrum. Methenamine hippurate is effective against most common urinary tract pathogens.

For research use only. We do not sell to patients.

Methenamine hippurate Chemical Structure

Methenamine hippurate Chemical Structure

CAS No. : 5714-73-8

Size Price Stock Quantity
100 mg USD 70 In-stock
Estimated Time of Arrival: December 31
250 mg USD 120 In-stock
Estimated Time of Arrival: December 31
500 mg USD 210 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Methenamine hippurate (Hexamine hippurate) is an orally active urinary antiseptic agent with a wide antibacterial spectrum. Methenamine hippurate is effective against most common urinary tract pathogens[1][2].

In Vitro

Methenamine hippurate is a urinary antibacterial agent which releases formaldehyde and is excreted in the urine. Methenamine hippurate has a demonstrable activity in vitro at pH 5 to 6 against Escherichia coli, Staphylococcus aureus, Aerobacter aeroaenes, Pseudomonas aeruginosa and Proteus vulgaris, and a wide range of action against Klebsiella pneumoniae, Ps. aeruginosa, E. coli, Staph. aureus and Streptococcus haemolytic at pH of 7.4. This action is more effective than that of Methenamine alone, of Hippuric acid alone or of Sulphadiazine[1].

Molecular Weight

319.36

Formula

C₁₅H₂₁N₅O₃

CAS No.

5714-73-8

SMILES

O=C(O)CNC(C1=CC=CC=C1)=O.N2(C3)CN4CN3CN(C4)C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (78.28 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1313 mL 15.6563 mL 31.3126 mL
5 mM 0.6263 mL 3.1313 mL 6.2625 mL
10 mM 0.3131 mL 1.5656 mL 3.1313 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

MethenamineHexamineBacterialurinaryantiseptictractpathogensbacterialurineInhibitorinhibitorinhibit

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Methenamine hippurate
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HY-B1691
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