Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
169 Results for "
neuroprotective properties
" in MedChemExpress (MCE) Product Catalog:
Products (169)
169 Results for "neuroprotective properties" in MCE Product Catalog:
72
72 Publications Verification
Cat. No.: HY-17412
CAS No.: 13614-98-7
Minocycline hydrochloride is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline hydrochloride is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline hydrochloride shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline hydrochloride reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline hydrochloride inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect .
72
72 Publications Verification
Cat. No.: HY-17412A
CAS No.: 10118-90-8
Minocycline is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect .
34
34 Cited Publications
Cat. No.: HY-W013075
CAS No.: 250249-75-3
Synonyms: Rutoside trihydrate; Quercetin 3-O-rutinoside trihydrate
Target:
22
20
20 Cited Publications
Cat. No.: HY-76201
CAS No.: 149003-01-0
Synonyms: ICRF-187 hydrochloride; ADR-529 hydrochloride; NSC-169780 hydrochloride
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Dexrazoxane hydrochloride (ICRF-187 hydrochloride) is a heart protectant that can help preserve ovarian function and fertility. Dexrazoxane hydrochloride has antioxidant and anti-inflammatory properties, can cross the blood-brain barrier, improves motor function disorders, and offers neuroprotective effects, making it useful in the study of neurodegenerative diseases .
10
10 Cited Publications
Cat. No.: HY-N0057
CAS No.: 14534-61-3
Synonyms: 3,4-Di-O-caffeoylquinic acid; Isochlorogenic acid B
9
9 Cited Publications
Cat. No.: HY-N0625A
CAS No.: 36052-37-6
Category:
Alpinia katsumadai Hayata Plants Flavonoids Monophenols Flavonones Phenols Disease Research Fields Inflammation/Immunology Cancer Zingiberaceae
Target:
9
9 Cited Publications
Target:
Research Areas:
AS601245 is an orally active, selective, ATP competitive JNK (c-Jun NH2-terminal protein kinase) inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively. AS601245 exhibits 10- to 20-fold selectivity over c-src, CDK2, and c-Raf and more than 50- to 100-fold selectivity over a range of Ser/Thr- and Tyr-protein kinases. Neuroprotective properties .
8
8 Cited Publications
Target:
Research Areas:
PKR-IN-C16 (Compound C16) is a specific double-stranded RNA-dependent protein kinase (PKR) inhibitor. PKR-IN-C16 shows promising neuroprotective properties and can rescue acute brain lesions .
7
6
6 Cited Publications
Cat. No.: HY-N0405
CAS No.: 28608-75-5
Category:
other families Flavonoids Flavones Phenols Polyphenols Plants
Target:
6
Category:
Erythrina subumbrans (Hassk.) Merr. Terpenoids Sesquiterpenes Plants Compositae Endogenous metabolite Disease Research Fields Cancer
Target:
6
Category:
other families Flavonoids Monophenols Neurological Disease Flavones Phenols Plants Disease Research Fields Inflammation/Immunology
Target:
5
5
5 Cited Publications
Cat. No.: HY-N0201
CAS No.: 73069-13-3
Category:
Terpenoids Sesquiterpenes Astragalus caprinus L. Plants Compositae Disease Research Fields Cancer
Target:
5
Category:
other families Monophenols Coumarins Phenols Phenylpropanoids Plants Disease Research Fields Cancer
Target:
5
Research Areas:
Pamoic acid (Embonic acid) is a potent GPR35 agonist with an EC50 of 79 nM. Pamoic acid exhibits neuroprotective and anti-inflammatory properties .
5
Target:
Research Areas:
Tropisetron Hydrochloride (SDZ-ICS-930) is an effective neuroprotective agent that acts as a 5-HT3 receptor antagonist, a calmodulin inhibitor, and an α7-nAChRreceptor agonist, with an IC50 of 70.1 nM for the 5-HT3 receptor. Tropisetron Hydrochloride has anti-inflammatory properties and immune-regulating functions, effectively alleviating symptoms associated with chemotherapy and post-surgery. Tropisetron Hydrochloride reduces Ab (HY-P4867)-induced hippocampal neuroinflammation .
4
4 Cited Publications
Cat. No.: HY-N0408
CAS No.: 39012-20-9
4
Research Areas:
Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Probucol (DH-581) is an anti-hyperlipidemic agent. Probucol activates glutathione peroxidase. Probucol promotes low density lipoprotein (LDL) catabolism, inhibits ABCA1-dependent cholesterol efflux, and decreases HDL-C levels. Probucol also has anti-inflammatory, antioxidant and neuroprotective properties. Probucol can be used for researches on bone, cardiovascular, cancer, neurological, and metabolism-related diseases .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
