Lercanidipine-d3
Lercanidipine-d3 is the deuterium labeled Lercanidipine (HY-B0612). Lercanidipine is a third-generation, lipophilic, brain-penetrant, vascular-selective and orally active dihydropyridine-calcium channel blocker with a pIC50 of 7.74 (converts from μM). Lercanidipine has long lasting antihypertensive action as well as reno- and neuro-protective effect. Lercanidipine also shows anti-oxidant, anti-inflammatory and anti-apoptotic properties. Lercanidipine can be used in cardiovascular and neurological research.
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- No. CAS: 1190043-34-5
- Fòrmula: C36H38D3N3O6
- Peso molecular:614.75
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Aplicación
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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No. CAS 1190043-34-5
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Unlabeled CAS 100427-26-7
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Peso molecular 614.75
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Fòrmula C36H38D3N3O6
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SMILES
O=C(C1=C(NC(C)=C(C1C2=CC=CC([N+]([O-])=O)=C2)C(OC)=O)C)OC(C)(CN(CCC(C3=CC=CC=C3)C4=CC=CC=C4)C([2H])([2H])[2H])C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lercanidipine-d3 Related Classifications
HY-W707863 Related Classifications
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