Lercanidipine-d3
Lercanidipine-d3 is the deuterium labeled Lercanidipine (HY-B0612). Lercanidipine is a third-generation, lipophilic, brain-penetrant, vascular-selective and orally active dihydropyridine-calcium channel blocker with a pIC50 of 7.74 (converts from μM). Lercanidipine has long lasting antihypertensive action as well as reno- and neuro-protective effect. Lercanidipine also shows anti-oxidant, anti-inflammatory and anti-apoptotic properties. Lercanidipine can be used in cardiovascular and neurological research.
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- CAS No.: 1190043-34-5
- Formule: C36H38D3N3O6
- Masse moléculaire:614.75
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
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Help & FAQs
Activité biologique
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1190043-34-5
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Unlabeled CAS 100427-26-7
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Masse moléculaire 614.75
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Formule C36H38D3N3O6
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SMILES
O=C(C1=C(NC(C)=C(C1C2=CC=CC([N+]([O-])=O)=C2)C(OC)=O)C)OC(C)(CN(CCC(C3=CC=CC=C3)C4=CC=CC=C4)C([2H])([2H])[2H])C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lercanidipine-d3 Related Classifications
HY-W707863 Related Classifications
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