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Cat. No.: HY-120657R

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9-PAHSA (Standard)

Flumethrin (Standard) is the analytical standard of Flumethrin. This product is intended for research and analytical applications. 9-PAHSA is an orally active endogenous GPR120 agonist (EC₅₀=18 μM). 9-PAHSA significantly inhibits LPS-induced inflammatory responses by blocking the NF-κB pathway. 9-PAHSA induces adipocyte browning, enhances glucose uptake and reduces lipid accumulation, while improving mitochondrial function and the survival rate of steatotic hepatocytes. In terms of neuroprotection, 9-PAHSA regulates the expression of REST and BDNF in the prefrontal cortex of diabetic mice, and effectively prevents spatial working memory deficits and abnormal social behaviors. 9-PAHSA does not directly regulate insulin secretion or improve systemic insulin sensitivity, and possesses specific anti-inflammatory, metabolic regulatory and neuroprotective properties. 9-PAHSA can be used in the research of diabetes-related cognitive impairment, obesity and non-alcoholic fatty liver disease.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 1481636-31-0
Formule: C₃₄H₆₆O₄
Masse moléculaire:538.89

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Please store the product under the recommended conditions in the Certificate of Analysis.

9-PAHSA (Standard) Chemical Structure

CAS No.: 1481636-31-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 1481636-31-0
Masse moléculaire 538.89
Formule C₃₄H₆₆O₄
SMILES

OC(CCCCCCCC(CCCCCCCCC)OC(CCCCCCCCCCCCCCC)=O)=O
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Endogenous metabolite
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Références

[1]. Pflimlin E, et al. Acute and Repeated Treatment with 5-PAHSA or 9-PAHSA Isomers Does Not Improve Glucose Control in Mice. Cell Metab. 2018;28(2):217-227.e13. [Content Brief]

[2]. Wen XH, et al. Effect of 9 - PAHSA on cognitive dysfunction in diabetic mice and its possible mechanism. Biochem Biophys Res Commun. 2020;524(3):525-532. [Content Brief]

[3]. Wang Y M, et al. 9-PAHSA promotes browning of white fat via activating G-protein-coupled receptor 120 and inhibiting lipopolysaccharide/NF-kappa B pathway[J]. Biochemical and biophysical research communications, 2018, 506(1): 153-160.

[4]. Schultz Moreira AR, et al. 9-PAHSA Prevents Mitochondrial Dysfunction and Increases the Viability of Steatotic Hepatocytes. Int J Mol Sci. 2020;21(21):8279. Published 2020 Nov 5. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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9-PAHSA (Standard)

9-PAHSA

Methyl linoleate

C14 Ceramide

2-NBDG

Glucosylceramide, plant

Glucosylceramide (gaucher's spleen)

2-NBDG (solution)

Methyl linoleate (Standard)

LacCer (d18:1/16:0)

FKGK18

cis-11,14-Eicosadienoic acid methyl ester

C24 Dihydro ceramide (d18:0/24:0)

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9-PAHSA (Standard)

9-PAHSA

Methyl linoleate

C14 Ceramide

2-NBDG

Glucosylceramide, plant

Glucosylceramide (gaucher's spleen)

2-NBDG (solution)

Methyl linoleate (Standard)

LacCer (d18:1/16:0)

FKGK18

cis-11,14-Eicosadienoic acid methyl ester

C24 Dihydro ceramide (d18:0/24:0)

Product Information

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

9-PAHSA (Standard) Related Classifications

HY-120657R Related Classifications