1. GPCR/G Protein
    Neuronal Signaling
  2. 5-HT Receptor
  3. Tianeptine sodium salt

Tianeptine sodium salt 

Cat. No.: HY-90003A Purity: 99.82%
Handling Instructions

Tianeptine sodium salt is a selective facilitator of 5-HT uptake. Tianeptine sodium salt has no affinity for a wide range of receptors, including 5-HT and dopamine (IC50>10 μM) and has no effect on noradrenalin or dopamine uptake. Tianeptine sodium salt has antidepressant, anxiolytic, analgesic and neuroprotective activities.

For research use only. We do not sell to patients.

Tianeptine sodium salt Chemical Structure

Tianeptine sodium salt Chemical Structure

CAS No. : 30123-17-2

Size Stock
10 mM * 1 mL in DMSO Get quote
10 mg USD 60 Get quote
50 mg USD 78 Get quote
100 mg USD 114 Get quote

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Other Forms of Tianeptine sodium salt:

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Description

Tianeptine sodium salt is a selective facilitator of 5-HT uptake. Tianeptine sodium salt has no affinity for a wide range of receptors, including 5-HT and dopamine (IC50>10 μM) and has no effect on noradrenalin or dopamine uptake. Tianeptine sodium salt has antidepressant, anxiolytic, analgesic and neuroprotective activities[1][2][3][4].

IC50 & Target

serotonin

 

Clinical Trial
Molecular Weight

458.93

Formula

C₂₁H₂₄ClN₂NaO₄S

CAS No.

30123-17-2

SMILES

O=C(CCCCCCNC(C1=CC=CC=C1N2C)C3=CC=C(C=C3S2(=O)=O)Cl)O[Na]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (217.90 mM; Need ultrasonic)

H2O : 100 mg/mL (217.90 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1790 mL 10.8949 mL 21.7898 mL
5 mM 0.4358 mL 2.1790 mL 4.3580 mL
10 mM 0.2179 mL 1.0895 mL 2.1790 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (5.45 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (5.45 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (5.45 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

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The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Tianeptine5-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorInhibitorinhibitorinhibit

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Tianeptine sodium salt
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HY-90003A
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