1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. iGluR
  3. Conantokin G

Conantokin G 

Cat. No.: HY-P1293
Handling Instructions

Conantokin G, a 17-amino-acid peptide, is a potent, selective and competitive antagonist of N-methyl-D-aspartate (NMDA) receptors. Conantokin G inhibits NMDA-evoked currents in murine cortical neurons with an IC50 of 480 nM. Conantokin G has neuroprotective properties.

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Conantokin G Chemical Structure

Conantokin G Chemical Structure

CAS No. : 93438-65-4

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Description

Conantokin G, a 17-amino-acid peptide, is a potent, selective and competitive antagonist of N-methyl-D-aspartate (NMDA) receptors. Conantokin G inhibits NMDA-evoked currents in murine cortical neurons with an IC50 of 480 nM. Conantokin G has neuroprotective properties[1][2].

Molecular Weight

2264.19

Formula

C₈₈H₁₃₈N₂₆O₄₄

CAS No.

93438-65-4

Sequence Shortening

GE{Gla}{Gla}LQ{Gla}NQ{Gla}LIR{Gla}KSN-NH2

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Conantokin GiGluRIonotropic glutamate receptorsNMDAneuroprotectivemurinecorticalneuronsInhibitorinhibitorinhibit

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Conantokin G
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