1. GPCR/G Protein
    Neuronal Signaling
  2. Dopamine Receptor
  3. L-Stepholidine

L-Stepholidine (Synonyms: Stepholidine; (-)-Stepholidine; L-SPD)

Cat. No.: HY-N6960
Handling Instructions

L-Stepholidine (Stepholidine), an alkaloid extract of the Chinese herb Stephania intermedia, is the first compound known to exhibit mixed dopamine D1 receptor agonist/D2 antagonist properties. L-Stepholidine (Stepholidine) has neuroprotective effect and inhibits heroin-induced reinstatement. L-Stepholidine (Stepholidine) is a potential medication for the treatment of opiate addiction.

For research use only. We do not sell to patients.

L-Stepholidine Chemical Structure

L-Stepholidine Chemical Structure

CAS No. : 16562-13-3

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Description

L-Stepholidine (Stepholidine), an alkaloid extract of the Chinese herb Stephania intermedia, is the first compound known to exhibit mixed dopamine D1 receptor agonist/D2 antagonist properties. L-Stepholidine (Stepholidine) has neuroprotective effect and inhibits heroin-induced reinstatement. L-Stepholidine (Stepholidine) is a potential medication for the treatment of opiate addiction[1][2][3].

IC50 & Target

Dopamine D1 receptor[1]
Dopamine D2 receptor[1]

Molecular Weight

327.37

Formula

C₁₉H₂₁NO₄

CAS No.

16562-13-3

SMILES

OC1=C(OC)C=C(CCN2CC3=C(OC)C(O)=CC=C3C[[email protected]]24[H])C4=C1

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L-Stepholidine
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