Cerebrocrast
Cerebrocrast (IOS-1.1212) is a 1,4-dihydropyridine (DHP) derivative. Cerebrocrast has a high affinity for the membrane lipid bilayer and it can easily penetrate the blood-brain barrier and incorporate into the plasma and organelle membranes, including those of mitochondria. Cerebrocrast promotes the cotransport of H+ and Cl- in rat liver mitochondria. Cerebrocrast also exhibits neuroprotective and cognition enhancer properties.
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- CAS No.: 118790-71-9
- 화학식: C26H35F2NO7
- 분자량:511.56
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Calcium Channel Isoforms
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Biological Activity
Cerebrocrast (25 μM) inhibits the inner mitochondrial anion channel with an IC50 value of 10.5 ± 2.0 μM in rat liver mitochondria[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 118790-71-9
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Appearance Solid
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분자량 511.56
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화학식 C26H35F2NO7
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Color Off-white to light yellow
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SMILES
CCCOCCOC(C1=C(C)NC(C)=C(C(OCCOCCC)=O)C1C2=C(C=CC=C2)OC(F)F)=O
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Synonyms
IOS-1.1212
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
순도&문서
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)