118790-71-9
Chemical Structure
Cerebrocrast
Synonym(s): IOS-1.1212
- CAS No.: 118790-71-9
- Formula:C26H35F2NO7
- Molecular Weight:511.56
IUPAC Name: bis(2-propoxyethyl) 4-(2-(difluoromethoxy)phenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
InChIKey: ASCWBYZMMHUZMQ-UHFFFAOYSA-N
SMILES: CCCOCCOC(C1=C(C)NC(C)=C(C(OCCOCCC)=O)C1C2=C(C=CC=C2)OC(F)F)=O
Biological Activity: Cerebrocrast (IOS-1.1212) is a 1,4-dihydropyridine (DHP) derivative. Cerebrocrast has a high affinity for the membrane lipid bilayer and it can easily penetrate the blood-brain barrier and incorporate into the plasma and organelle membranes, including those of mitochondria. Cerebrocrast promotes the cotransport of H+ and Cl- in rat liver mitochondria. Cerebrocrast also exhibits neuroprotective and cognition enhancer properties[1][2].
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Cerebrocrast | Cerebrocrast (IOS-1.1212) is a 1,4-dihydropyridine (DHP) derivative. Cerebrocrast has a high affinity for the membrane lipid bilayer and it can easily penetrate the blood-brain barrier and incorporate into the plasma and organelle membranes, including those of mitochondria. Cerebrocrast promotes the cotransport of H+ and Cl- in rat liver mitochondria. Cerebrocrast also exhibits neuroprotective and cognition enhancer properties. | |||||||||||||||||||||
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