Huperzine C
Huperzine C is an alkaloid isolated from Huperzia serrate. Huperzine C is an acetylcholinesterase (AChE) inhibotor, with an IC50 of 0.6 μM. Huperzine C can be used for the research of Alzheimer’s disease.
For research use only. We do not sell to patients.
- CAS No.: 163089-71-2
- Formula: C15H18N2O
- Molecular Weight:242.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
IC50: 0.6 μM (AChE)[2]
Chemical Information
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CAS No. 163089-71-2
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Molecular Weight 242.32
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Formula C15H18N2O
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SMILES
O=C1C=CC([C@@]([C@@H]2C=C)(N)CC(C)=C[C@@]2([H])C3)=C3N1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
[1]. Fangfang Jiang, et al. Lycopodium alkaloids from Huperzia serrate. Fitoterapia.. 2019 Sep;137:104277. [Content Brief]
[2]. Dong-Bo Zhang, et al. Lycodine-Type Alkaloids from Lycopodiastrum casuarinoides and Their Acetylcholinesterase Inhibitory Activity. Molecules. 2014 Jul; 19(7): 9999–10010. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Huperzine C Related Classifications
HY-122957 Related Classifications
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